Jesse D. Bloom
Jesse D. Bloom
Fred Hutch Cancer Research Center; University of Washington; Howard Hughes Medical Institute
Verified email at - Homepage
Cited by
Cited by
Protein stability promotes evolvability
JD Bloom, ST Labthavikul, CR Otey, FH Arnold
Proceedings of the National Academy of Sciences 103 (15), 5869-5874, 2006
Why highly expressed proteins evolve slowly
DA Drummond, JD Bloom, C Adami, CO Wilke, FH Arnold
Proceedings of the National Academy of Sciences 102 (40), 14338-14343, 2005
Permissive secondary mutations enable the evolution of influenza oseltamivir resistance
JD Bloom, LI Gong, D Baltimore
Science 328 (5983), 1272-1275, 2010
In the light of directed evolution: pathways of adaptive protein evolution
JD Bloom, FH Arnold
Proceedings of the National Academy of Sciences 106 (Supplement 1), 9995-10000, 2009
Evolving strategies for enzyme engineering
JD Bloom, MM Meyer, P Meinhold, CR Otey, D MacMillan, FH Arnold
Current opinion in structural biology 15 (4), 447-452, 2005
Thermodynamic prediction of protein neutrality
JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
Proceedings of the National Academy of Sciences 102 (3), 606-611, 2005
Stability-mediated epistasis constrains the evolution of an influenza protein
LI Gong, MA Suchard, JD Bloom
Elife 2, e00631, 2013
Structure-guided recombination creates an artificial family of cytochromes P450
CR Otey, M Landwehr, JB Endelman, K Hiraga, JD Bloom, FH Arnold
PLoS Biol 4 (5), e112, 2006
Structural determinants of the rate of protein evolution in yeast
JD Bloom, DA Drummond, FH Arnold, CO Wilke
Molecular biology and evolution 23 (9), 1751-1761, 2006
Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein–protein interactions data sets
JD Bloom, C Adami
BMC evolutionary biology 3 (1), 1-10, 2003
A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments
Y Li, DA Drummond, AM Sawayama, CD Snow, JD Bloom, FH Arnold
Nature biotechnology 25 (9), 1051-1056, 2007
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
JD Bloom, PA Romero, Z Lu, FH Arnold
Biology direct 2 (1), 17, 2007
The interface of protein structure, protein biophysics, and molecular evolution
DA Liberles, SA Teichmann, I Bahar, U Bastolla, J Bloom, ...
Protein Science 21 (6), 769-785, 2012
Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013–2014 influenza season
SL Linderman, BS Chambers, SJ Zost, K Parkhouse, Y Li, C Herrmann, ...
Proceedings of the National Academy of Sciences 111 (44), 15798-15803, 2014
Thermodynamics of neutral protein evolution
JD Bloom, A Raval, CO Wilke
Genetics 175 (1), 255-266, 2007
The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin
B Thyagarajan, JD Bloom
Elife 3, e03300, 2014
An experimentally determined evolutionary model dramatically improves phylogenetic fit
JD Bloom
Molecular Biology and Evolution 31 (8), 1956-1978, 2014
The elongation of yeast prion fibers involves separable steps of association and conversion
T Scheibel, J Bloom, SL Lindquist
Proceedings of the National Academy of Sciences 101 (8), 2287-2292, 2004
Stability and the evolvability of function in a model protein
JD Bloom, CO Wilke, FH Arnold, C Adami
Biophysical Journal 86 (5), 2758-2764, 2004
Accurate measurement of the effects of all amino-acid mutations on influenza hemagglutinin
MB Doud, JD Bloom
Viruses 8 (6), 155, 2016
The system can't perform the operation now. Try again later.
Articles 1–20