A highly selective turn-on fluorescent probe for iron (II) to visualize labile iron in living cells T Hirayama, K Okuda, H Nagasawa Chemical science 4 (3), 1250-1256, 2013 | 271 | 2013 |
Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor M Taki, M Desaki, A Ojida, S Iyoshi, T Hirayama, I Hamachi, Y Yamamoto Journal of the American Chemical Society 130 (38), 12564-12565, 2008 | 213 | 2008 |
Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model T Hirayama, GC Van de Bittner, LW Gray, S Lutsenko, CJ Chang Proceedings of the National Academy of Sciences 109 (7), 2228-2233, 2012 | 208 | 2012 |
A universal fluorogenic switch for Fe (ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic … T Hirayama, H Tsuboi, M Niwa, A Miki, S Kadota, Y Ikeshita, K Okuda, ... Chemical science 8 (7), 4858-4866, 2017 | 129 | 2017 |
Chemical tools for detecting Fe ions T Hirayama, H Nagasawa Journal of clinical biochemistry and nutrition 60 (1), 39-48, 2017 | 126 | 2017 |
Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia Z Li, L Jiang, SH Chew, T Hirayama, Y Sekido, S Toyokuni Redox biology 26, 101297, 2019 | 105 | 2019 |
A new class of high-contrast Fe (II) selective fluorescent probes based on spirocyclized scaffolds for visualization of intracellular labile iron delivered by transferrin M Niwa, T Hirayama, K Okuda, H Nagasawa Organic & biomolecular chemistry 12 (34), 6590-6597, 2014 | 101 | 2014 |
Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy L Shi, F Ito, Y Wang, Y Okazaki, H Tanaka, M Mizuno, M Hori, T Hirayama, ... Free Radical Biology and Medicine 108, 904-917, 2017 | 86 | 2017 |
Iron stimulates plasma-activated medium-induced A549 cell injury T Adachi, S Nonomura, M Horiba, T Hirayama, T Kamiya, H Nagasawa, ... Scientific reports 6 (1), 20928, 2016 | 84 | 2016 |
A Golgi-targeting fluorescent probe for labile Fe (ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35 T Hirayama, M Inden, H Tsuboi, M Niwa, Y Uchida, Y Naka, I Hozumi, ... Chemical science 10 (5), 1514-1521, 2019 | 69 | 2019 |
Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli Z Xu, P Wang, H Wang, ZH Yu, HY Au-Yeung, T Hirayama, H Sun, A Yan Journal of Biological Chemistry 294 (45), 16978-16991, 2019 | 67 | 2019 |
Intracellular Fe2+ accumulation in endothelial cells and pericytes induces blood-brain barrier dysfunction in secondary brain injury after brain hemorrhage T Imai, S Iwata, T Hirayama, H Nagasawa, S Nakamura, M Shimazawa, ... Scientific reports 9 (1), 6228, 2019 | 65 | 2019 |
Facile One‐Pot Synthesis of [1, 2, 3]Triazolo[1, 5‐a]Pyridines from 2‐Acylpyridines by Copper(II)‐Catalyzed Oxidative NN Bond Formation T Hirayama, S Ueda, T Okada, N Tsurue, K Okuda, H Nagasawa Chemistry–A European Journal 20 (14), 4156-4162, 2014 | 65 | 2014 |
Organelle-specific analysis of labile Fe(ii) during ferroptosis by using a cocktail of various colour organelle-targeted fluorescent probes T Hirayama, A Miki, H Nagasawa Metallomics 11 (1), 111-117, 2019 | 63 | 2019 |
Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model T Mukaide, Y Hattori, N Misawa, S Funahashi, L Jiang, T Hirayama, ... Free radical research 48 (9), 990-995, 2014 | 61 | 2014 |
Fluorescent probes for the detection of catalytic Fe (II) ion T Hirayama Free Radical Biology and Medicine 133, 38-45, 2019 | 59 | 2019 |
FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes M Tsuji, S Ueda, T Hirayama, K Okuda, Y Sakaguchi, A Isono, ... Organic & biomolecular chemistry 11 (18), 3030-3037, 2013 | 53 | 2013 |
Fe (II) ion release during endocytotic uptake of iron visualized by a membrane-anchoring Fe (II) fluorescent probe M Niwa, T Hirayama, I Oomoto, DO Wang, H Nagasawa ACS chemical biology 13 (7), 1853-1861, 2018 | 49 | 2018 |
Contrasting intra-and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis F Ito, T Nishiyama, L Shi, M Mori, T Hirayama, H Nagasawa, H Yasui, ... Biochemical and biophysical research communications 476 (4), 600-606, 2016 | 47 | 2016 |
A mitochondria-targeted fluorescent probe for selective detection of mitochondrial labile Fe(ii) T Hirayama, S Kadota, M Niwa, H Nagasawa Metallomics 10 (6), 794-801, 2018 | 45 | 2018 |