| Pleiotrophin regulates microglia-mediated neuroinflammation R Fernández-Calle, M Vicente-Rodríguez, E Gramage, J Pita, ... Journal of Neuroinflammation 14 (1), 46, 2017 | 69 | 2017 |
| Connecting metainflammation and neuroinflammation through the PTN-MK-RPTPβ/ζ axis: relevance in therapeutic development G Herradon, MP Ramos-Alvarez, E Gramage Frontiers in Pharmacology 10, 377, 2019 | 56 | 2019 |
| Genetic inactivation of pleiotrophin triggers amphetamine-induced cell loss in the substantia nigra and enhances amphetamine neurotoxicity in the striatum E Gramage, L Rossi, N Granado, R Moratalla, G Herradón Neuroscience 170 (1), 308-316, 2010 | 53 | 2010 |
| The neurotrophic factor pleiotrophin modulates amphetamine‐seeking behaviour and amphetamine‐induced neurotoxic effects: evidence from pleiotrophin knockout mice E Gramage, A Putelli, MJ Polanco, C González‐Martín, L Ezquerra, ... Addiction biology 15 (4), 403-412, 2010 | 52 | 2010 |
| Midkine regulates amphetamine-induced astrocytosis in striatum but has no effects on amphetamine-induced striatal dopaminergic denervation and addictive effects: functional … E Gramage, YB Martín, P Ramanah, C Pérez-García, G Herradón Neuroscience 190, 307-317, 2011 | 51* | 2011 |
| Connecting Parkinson's disease and drug addiction: common players reveal unexpected disease connections and novel therapeutic approaches E Gramage, G Herradon Current pharmaceutical design 17 (5), 449-461, 2011 | 50 | 2011 |
| The expression and function of midkine in the vertebrate retina E Gramage, J Li, P Hitchcock British journal of pharmacology 171 (4), 913-923, 2014 | 41 | 2014 |
| Pleiotrophin prevents cocaine-induced toxicity in vitro E Gramage, LF Alguacil, G Herradon European journal of pharmacology 595 (1-3), 35-38, 2008 | 35 | 2008 |
| Targeting the pleiotrophin/receptor protein tyrosine phosphatase β/ζ signaling pathway to limit neurotoxicity induced by drug abuse G Herradón, L Ezquerra, E Gramage, LF Alguacil Mini reviews in medicinal chemistry 9 (4), 440-447, 2009 | 33 | 2009 |
| Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders M Pastor, R Fernandez-Calle, B Di Geronimo, M Vicente-Rodriguez, ... European journal of medicinal chemistry 144, 318-329, 2018 | 32 | 2018 |
| Regulation of extinction of cocaine-induced place preference by midkine is related to a differential phosphorylation of peroxiredoxin 6 in dorsal striatum. E Gramage, C Pérez-García, M Vicente-Rodríguez, S Bollen, L Rojo, ... Behavioural brain research 253, 223-231, 2013 | 31 | 2013 |
| Pleiotrophin inhibits hippocampal long-term potentiation: a role of pleiotrophin in learning and memory N del Olmo, E Gramage, LF Alguacil, P Pérez-Pinera, TF Deuel, ... Growth Factors 27 (3), 189-194, 2009 | 30 | 2009 |
| Midkine-a Protein Localization in the Developing and Adult Retina of the Zebrafish and Its Function During Photoreceptor Regeneration E Gramage, T D’Cruz, S Taylor, R Thummel, PF Hitchcock PloS one 10 (3), e0121789, 2015 | 28 | 2015 |
| Phosphoproteomic analysis of the striatum from pleiotrophin knockout and midkine knockout mice treated with cocaine reveals regulation of oxidative stress-related proteins … M Vicente-Rodríguez, E Gramage, G Herradón, C Pérez-García Toxicology 314 (1), 166-173, 2013 | 28 | 2013 |
| Differential phosphoproteome of the striatum from pleiotrophin knockout and midkine knockout mice treated with amphetamine: Correlations with amphetamine-induced neurotoxicity E Gramage, G Herradón, YB Martín, M Vicente-Rodríguez, L Rojo, ... Toxicology 306, 147-156, 2013 | 26 | 2013 |
| Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol R Fernández-Calle, M Vicente-Rodríguez, M Pastor, E Gramage, ... Neuropharmacology 137, 86-95, 2018 | 25 | 2018 |
| Periadolescent amphetamine treatment causes transient cognitive disruptions and long‐term changes in hippocampal LTP depending on the endogenous expression of pleiotrophin E Gramage, N Del Olmo, A Fole, YB Martín, G Herradón Addiction biology 18 (1), 19-29, 2013 | 23 | 2013 |
| Pleiotrophin deletion alters glucose homeostasis, energy metabolism and brown fat thermogenic function in mice J Sevillano, MG Sánchez-Alonso, B Zapatería, M Calderón, M Alcalá, ... Diabetologia 62, 123-135, 2019 | 22 | 2019 |
| Genetic deletion of pleiotrophin leads to disruption of spinal nociceptive transmission: evidence for pleiotrophin modulation of morphine-induced analgesia E Gramage, G Herradon European journal of pharmacology 647 (1-3), 97-102, 2010 | 22 | 2010 |
| Endogenous pleiotrophin and midkine regulate LPS-induced glial responses R Fernández-Calle, M Vicente-Rodríguez, E Gramage, C de la Torre-Ortiz, ... Neuroscience Letters 662, 213-218, 2018 | 20 | 2018 |
