Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons ET Coffey, V Hongisto, M Dickens, RJ Davis, MJ Courtney Journal of Neuroscience 20 (20), 7602-7613, 2000 | 235 | 2000 |
Miswiring the brain: Δ9‐tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin‐2 degradation pathway G Tortoriello, CV Morris, A Alpar, J Fuzik, SL Shirran, D Calvigioni, ... The EMBO journal 33 (7), 668-685, 2014 | 233 | 2014 |
Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector B Björkblom, N Östman, V Hongisto, V Komarovski, JJ Filén, TA Nyman, ... Journal of Neuroscience 25 (27), 6350-6361, 2005 | 219 | 2005 |
JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length T Tararuk, N Östman, W Li, B Björkblom, A Padzik, J Zdrojewska, ... The Journal of cell biology 173 (2), 265-277, 2006 | 215 | 2006 |
c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons ET Coffey, G Smiciene, V Hongisto, J Cao, S Brecht, T Herdegen, ... Journal of Neuroscience 22 (11), 4335-4345, 2002 | 215 | 2002 |
The PSD95–nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death J Cao, JI Viholainen, C Dart, HK Warwick, ML Leyland, MJ Courtney The Journal of cell biology 168 (1), 117-126, 2005 | 194 | 2005 |
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells MJ Courtney, JJ Lambert, DG Nicholls Journal of Neuroscience 10 (12), 3873-3879, 1990 | 184 | 1990 |
Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3 V Hongisto, N Smeds, S Brecht, T Herdegen, MJ Courtney, ET Coffey Molecular and cellular biology, 2003 | 172 | 2003 |
Rho mediates calcium-dependent activation of p38α and subsequent excitotoxic cell death MM Semenova, AMJ Mäki-Hokkonen, J Cao, V Komarovski, KM Forsberg, ... Nature neuroscience 10 (4), 436-443, 2007 | 135 | 2007 |
Distinct requirements for p38α and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death J Cao, MM Semenova, VT Solovyan, J Han, ET Coffey, MJ Courtney Journal of Biological Chemistry 279 (34), 35903-35913, 2004 | 132 | 2004 |
Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate N Westerlund, J Zdrojewska, A Padzik, E Komulainen, B Björkblom, ... Nature neuroscience 14 (3), 305-313, 2011 | 124 | 2011 |
Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a twocomponent mechanism MJ Courtney, KEO Åkerman, ET Coffey Journal of Neuroscience 17 (11), 4201-4211, 1997 | 124 | 1997 |
All JNKs can kill, but nuclear localization is critical for neuronal death B Bjorkblom, JC Vainio, V Hongisto, T Herdegen, MJ Courtney, ET Coffey Journal of biological chemistry 283 (28), 19704-19713, 2008 | 107 | 2008 |
The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death LL Li, V Ginet, X Liu, O Vergun, M Tuittila, M Mathieu, C Bonny, J Puyal, ... Journal of Neuroscience 33 (19), 8185-8201, 2013 | 105 | 2013 |
The role of topoisomerase II in the excision of DNA loop domains during apoptosis VT Solovyan, ZA Bezvenyuk, A Salminen, CA Austin, MJ Courtney Journal of Biological Chemistry 277 (24), 21458-21467, 2002 | 98 | 2002 |
Calpains are downstream effectors of bax-dependent excitotoxic apoptosis B D'Orsi, H Bonner, LP Tuffy, H Düssmann, I Woods, MJ Courtney, ... Journal of Neuroscience 32 (5), 1847-1858, 2012 | 93 | 2012 |
c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells B Björkblom, A Padzik, H Mohammad, N Westerlund, E Komulainen, ... Molecular and cellular biology 32 (17), 3513-3526, 2012 | 87 | 2012 |
Interactions between phospholipase C‐coupled and N‐methyl‐D‐aspartate receptors in cultured cerebellar granule cells: Protein kinase C mediated inhibition of N‐methyl‐D … MJ Courtney, DG Nicholls Journal of neurochemistry 59 (3), 983-992, 1992 | 85 | 1992 |
Brain derived neurotrophic factor induces a rapid upregulation of synaptophysin and tau proteins via the neurotrophin receptor TrkB in rat cerebellar granule cells ET Coffey, KEO Åkerman, MJ Courtney Neuroscience letters 227 (3), 177-180, 1997 | 80 | 1997 |
Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis SEF Tran, A Meinander, TH Holmström, A Rivero-Müller, KM Heiskanen, ... Cell Death & Differentiation 10 (10), 1137-1147, 2003 | 76 | 2003 |