| Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair JR Walker, RA Corpina, J Goldberg Nature 412 (6847), 607-614, 2001 | 1609 | 2001 |
| Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1 GV Avvakumov, JR Walker, S Xue, Y Li, S Duan, C Bronner, ... Nature 455 (7214), 822-825, 2008 | 533 | 2008 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 315 | 2013 |
| Architecture of Eph receptor clusters JP Himanen, L Yermekbayeva, PW Janes, JR Walker, K Xu, L Atapattu, ... Proceedings of the National Academy of Sciences 107 (24), 10860-10865, 2010 | 312 | 2010 |
| Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases TL Davis, JR Walker, V Campagna-Slater, PJ Finerty Jr, R Paramanathan, ... PLoS biology 8 (7), e1000439, 2010 | 311 | 2010 |
| Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms M Vedadi, J Lew, J Artz, M Amani, Y Zhao, A Dong, GA Wasney, M Gao, ... Molecular and biochemical parasitology 151 (1), 100-110, 2007 | 304 | 2007 |
| In situ proteolysis for protein crystallization and structure determination A Dong, X Xu, AM Edwards Nature methods 4 (12), 1019-1021, 2007 | 290 | 2007 |
| Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein N Nady, A Lemak, JR Walker, GV Avvakumov, MS Kareta, M Achour, ... Journal of Biological Chemistry 286 (27), 24300-24311, 2011 | 236 | 2011 |
| Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8) GV Avvakumov, JR Walker, S Xue, PJ Finerty, F Mackenzie, EM Newman, ... Journal of biological chemistry 281 (49), 38061-38070, 2006 | 175 | 2006 |
| System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes W Zhang, KP Wu, MA Sartori, HB Kamadurai, A Ordureau, C Jiang, ... Molecular cell 62 (1), 121-136, 2016 | 173 | 2016 |
| A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen Y Sheng, JH Hong, R Doherty, T Srikumar, J Shloush, GV Avvakumov, ... Molecular & Cellular Proteomics 11 (8), 329-341, 2012 | 134 | 2012 |
| The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1 F Syeda, RL Fagan, M Wean, GV Avvakumov, JR Walker, S Xue, ... Journal of Biological Chemistry 286 (17), 15344-15351, 2011 | 126 | 2011 |
| Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors Y Choi, F Syeda, JR Walker, PJ Finerty Jr, D Cuerrier, A Wojciechowski, ... Bioorganic & medicinal chemistry letters 19 (15), 4467-4470, 2009 | 100 | 2009 |
| Glyoxylate and pyruvate are antagonistic effectors of the Escherichia coli IclR transcriptional regulator GL Lorca, A Ezersky, VV Lunin, JR Walker, S Altamentova, E Evdokimova, ... Journal of biological chemistry 282 (22), 16476-16491, 2007 | 97 | 2007 |
| Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants PL Taylor, KM Blakely, GP De Leon, JR Walker, F McArthur, ... Journal of Biological Chemistry 283 (5), 2835-2845, 2008 | 91 | 2008 |
| Discovery of a PCAF Bromodomain Chemical Probe. M Moustakim, CP G. K., L Trulli, AL Fuentes de Arriba, MT Ehebauer, ... Angew Chem Int Ed Engl. 56 (3), 827–831, 2017 | 88 | 2017 |
| Post-translational modifications of TRF1 and TRF2 and their roles in telomere maintenance JR Walker, XD Zhu Mechanisms of ageing and development 133 (6), 421-434, 2012 | 82 | 2012 |
| Structure of Human Pancreatic Lipase-Related Protein 2 with the Lid in an Open Conformation, C Eydoux, S Spinelli, TL Davis, JR Walker, A Seitova, S Dhe-Paganon, ... Biochemistry 47 (36), 9553-9564, 2008 | 77 | 2008 |
| X-ray Crystal Structure of a Galactose-Specific C-Type Lectin Possessing a Novel Decameric Quaternary Structure, JR Walker, B Nagar, NM Young, T Hirama, JM Rini Biochemistry 43 (13), 3783-3792, 2004 | 77 | 2004 |
| Crystal structure of the human ubiquitin-activating enzyme 5 (UBA5) bound to ATP: mechanistic insights into a minimalistic E1 enzyme JP Bacik, JR Walker, M Ali, AD Schimmer, S Dhe-Paganon Journal of biological chemistry 285 (26), 20273-20280, 2010 | 73 | 2010 |
Xu-Dong ZhuMcMaster UniversityVerified email at mcmaster.ca
