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Sebastian Wrighton
Sebastian Wrighton
Postdoctoral researcher
Dirección de correo verificada de med.lu.se
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Spike-dependent opsonization indicates both dose-dependent inhibition of phagocytosis and that non-neutralizing antibodies can confer protection to SARS-CoV-2
W Bahnan, S Wrighton, M Sundwall, A Bläckberg, O Larsson, U Höglund, ...
Frontiers in immunology 12, 808932, 2022
512022
High-sensitivity assessment of phagocytosis by persistent association-based normalization
T de Neergaard, M Sundwall, S Wrighton, P Nordenfelt
The Journal of Immunology 206 (1), 214-224, 2021
182021
Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization
A Izadi, A Hailu, M Godzwon, S Wrighton, B Olofsson, T Schmidt, ...
Proceedings of the National Academy of Sciences 120 (15), e2217590120, 2023
142023
A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function
W Bahnan, L Happonen, H Khakzad, V Kumra Ahnlide, T de Neergaard, ...
EMBO Molecular Medicine 15 (2), e16208, 2023
13*2023
Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound
S Wrighton, VK Ahnlide, O André, W Bahnan, P Nordenfelt
Frontiers in microbiology 14, 1069789, 2023
62023
Nanoscale binding site localization by molecular distance estimation on native cell surfaces using topological image averaging
V Kumra Ahnlide, J Kumra Ahnlide, S Wrighton, JP Beech, P Nordenfelt
Elife 11, e64709, 2022
42022
IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies
IM Frick, L Happonen, S Wrighton, P Nordenfelt, L Björck
Journal of Biological Chemistry 299 (11), 2023
22023
Short‐term exposure to urban PM2.5 particles induces histopathological and inflammatory changes in the rat small intestine
L Ohlsson, C Isaxon, S Wrighton, W El Ouahidi, L Fornell, L Uller, S Ansar, ...
Physiological Reports 10 (7), e15249, 2022
12022
The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies
A Izadi, Y Karami, E Bratanis, S Wrighton, H Khakzad, M Nyblom, ...
Nature Communications 15 (1), 3600, 2024
2024
Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection
M Anthofer, M Windisch, R Haller, S Ehmann, S Wrighton, M Miller, ...
Frontiers in Immunology 15, 1282680, 2024
2024
The increased hinge flexibility of an IgG1-IgG3 hybrid monoclonal enhances Fc-mediated protection against group A streptococci
A Izadi, Y Karami, E Bratanis, S Wrighton, H Khakzad, M Nyblom, ...
bioRxiv, 2023.10. 14.562368, 2023
2023
Exploring Monoclonal Antibody Action Against the Group A Streptococcal M Protein
S Wrighton
2023
Nanoscale binding site localization by molecular distance estimation on native cell surfaces using topological image averaging
VK Ahnlide, JK Ahnlide, S Wrighton, JP Beech, P Nordenfelt
Elife 11, 2022
2022
SEPARATION OF SINGLETS AND CLUSTERS OF GROUP A STREPTOCOCCI USING DETERMINISTIC LATERAL DISPLACEMENT AND FILTER SONICATION
E Akbari, JP Beech, S Wrighton, P Nordenfelt, JO Tegenfeldt
26th International Conference on Miniaturized Systems for Chemistry and Life …, 2022
2022
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