|Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism|
H Zhao, L Yang, J Baddour, A Achreja, V Bernard, T Moss, JC Marini, ...
elife 5, e10250, 2016
|Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer|
L Yang, T Moss, LS Mangala, J Marini, H Zhao, S Wahlig, G Armaiz‐Pena, ...
Molecular systems biology 10 (5), 728, 2014
|Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth|
L Yang, A Achreja, TL Yeung, LS Mangala, D Jiang, C Han, J Baddour, ...
Cell metabolism 24 (5), 685-700, 2016
|Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer|
P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ...
Nature 542 (7639), 119-123, 2017
|The key role of extracellular vesicles in the metastatic process|
H Zhao, A Achreja, E Iessi, M Logozzi, D Mizzoni, R Di Raimo, D Nagrath, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 64-77, 2018
|Nitric oxide: The forgotten child of tumor metabolism|
BS Rizi, A Achreja, D Nagrath
Trends in cancer 3 (9), 659-672, 2017
|Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts|
TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ...
Elife 8, e50663, 2019
|Amplification of USP13 drives ovarian cancer metabolism|
C Han, L Yang, HH Choi, J Baddour, A Achreja, Y Liu, Y Li, J Li, G Wan, ...
Nature communications 7 (1), 1-16, 2016
|Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours|
Z Zhu, A Achreja, N Meurs, O Animasahun, S Owen, A Mittal, P Parikh, ...
Nature metabolism 2 (8), 775-792, 2020
|Exo-MFA–a 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism|
A Achreja, H Zhao, L Yang, TH Yun, J Marini, D Nagrath
Metabolic engineering 43, 156-172, 2017
|Mutant Kras-and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma|
HQ Ju, H Ying, T Tian, J Ling, J Fu, Y Lu, M Wu, L Yang, A Achreja, ...
Nature communications 8 (1), 1-14, 2017
|Role of Increased n-acetylaspartate Levels in Cancer|
B Zand, RA Previs, NM Zacharias, R Rupaimoole, T Mitamura, ...
JNCI: Journal of the National Cancer Institute 108 (6), 2016
|Generation of human fatty livers using custom-engineered induced pluripotent stem cells with modifiable SIRT1 metabolism|
AC de l’Hortet, K Takeishi, J Guzman-Lepe, K Morita, A Achreja, ...
Cell metabolism 30 (2), 385-401. e9, 2019
|Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma|
R Bajpai, A Sharma, A Achreja, CL Edgar, C Wei, AA Siddiqa, VA Gupta, ...
Nature communications 11 (1), 1-16, 2020
|Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel|
K Han, J Nam, J Xu, X Sun, X Huang, O Animasahun, A Achreja, JH Jeon, ...
Nature biomedical engineering 5 (11), 1377-1388, 2021
|ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment|
CL Au-Yeung, TL Yeung, A Achreja, H Zhao, KP Yip, SY Kwan, M Onstad, ...
Nature communications 11 (1), 1-16, 2020
|Cellular location of HNF4α is linked with terminal liver failure in humans|
RM Florentino, NA Fraunhoffer, K Morita, K Takeishi, A Ostrowska, ...
Hepatology communications 4 (6), 859-875, 2020
|Synthetic lethality: a step forward for personalized medicine in cancer|
H Jariyal, F Weinberg, A Achreja, D Nagarath, A Srivastava
Drug Discovery Today 25 (2), 305-320, 2020
|Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas|
P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ...
Science translational medicine 13 (614), eabc0497, 2021
|Quantifying metabolic transfer mediated by extracellular vesicles using Exo-MFA: an integrated empirical and computational platform|
A Achreja, N Meurs, D Nagrath
Metabolic Flux Analysis in Eukaryotic Cells, 205-221, 2020