| Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism H Zhao, L Yang, J Baddour, A Achreja, V Bernard, T Moss, JC Marini, ... elife 5, e10250, 2016 | 905 | 2016 |
| Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth L Yang, A Achreja, TL Yeung, LS Mangala, D Jiang, C Han, J Baddour, ... Cell metabolism 24 (5), 685-700, 2016 | 414 | 2016 |
| Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer L Yang, T Moss, LS Mangala, J Marini, H Zhao, S Wahlig, G Armaiz‐Pena, ... Molecular systems biology 10 (5), 728, 2014 | 375 | 2014 |
| Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 279 | 2017 |
| Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel K Han, J Nam, J Xu, X Sun, X Huang, O Animasahun, A Achreja, JH Jeon, ... Nature biomedical engineering 5 (11), 1377-1388, 2021 | 176 | 2021 |
| The key role of extracellular vesicles in the metastatic process H Zhao, A Achreja, E Iessi, M Logozzi, D Mizzoni, R Di Raimo, D Nagrath, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 64-77, 2018 | 173 | 2018 |
| Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours Z Zhu, A Achreja, N Meurs, O Animasahun, S Owen, A Mittal, P Parikh, ... Nature Metabolism 2 (8), 775-792, 2020 | 157 | 2020 |
| Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... elife 8, e50663, 2019 | 144 | 2019 |
| Nitric oxide: the forgotten child of tumor metabolism BS Rizi, A Achreja, D Nagrath Trends in cancer 3 (9), 659-672, 2017 | 120 | 2017 |
| Amplification of USP13 drives ovarian cancer metabolism C Han, L Yang, HH Choi, J Baddour, A Achreja, Y Liu, Y Li, J Li, G Wan, ... Nature communications 7 (1), 13525, 2016 | 114 | 2016 |
| Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma R Bajpai, A Sharma, A Achreja, CL Edgar, C Wei, AA Siddiqa, VA Gupta, ... Nature communications 11 (1), 1228, 2020 | 92 | 2020 |
| Mutant Kras-and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma HQ Ju, H Ying, T Tian, J Ling, J Fu, Y Lu, M Wu, L Yang, A Achreja, ... Nature communications 8 (1), 14437, 2017 | 87 | 2017 |
| Role of Increased n-acetylaspartate Levels in Cancer B Zand, RA Previs, NM Zacharias, R Rupaimoole, T Mitamura, ... Journal of the National Cancer Institute 108 (6), djv426, 2016 | 86 | 2016 |
| Generation of human fatty livers using custom-engineered induced pluripotent stem cells with modifiable SIRT1 metabolism AC de l’Hortet, K Takeishi, J Guzman-Lepe, K Morita, A Achreja, ... Cell metabolism 30 (2), 385-401. e9, 2019 | 80 | 2019 |
| Exo-MFA–a 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism A Achreja, H Zhao, L Yang, TH Yun, J Marini, D Nagrath Metabolic engineering 43, 156-172, 2017 | 76 | 2017 |
| ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment CL Au-Yeung, TL Yeung, A Achreja, H Zhao, KP Yip, SY Kwan, M Onstad, ... Nature communications 11 (1), 3546, 2020 | 43 | 2020 |
| Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas P Panwalkar, B Tamrazi, D Dang, C Chung, S Sweha, SK Natarajan, ... Science translational medicine 13 (614), eabc0497, 2021 | 38 | 2021 |
| Radiotherapy-induced metabolic hallmarks in the tumor microenvironment A Mittal, M Nenwani, I Sarangi, A Achreja, TS Lawrence, D Nagrath Trends in Cancer 8 (10), 855-869, 2022 | 37 | 2022 |
| Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer A Achreja, T Yu, A Mittal, S Choppara, O Animasahun, M Nenwani, ... Nature Metabolism 4 (9), 1119-1137, 2022 | 27 | 2022 |
| Synthetic lethality: a step forward for personalized medicine in cancer H Jariyal, F Weinberg, A Achreja, D Nagarath, A Srivastava Drug Discovery Today 25 (2), 305-320, 2020 | 26 | 2020 |
Deepak NagrathDepartment of Biomedical Engineering, University of MichiganVerified email at umich.edu
