| Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015 | 1239 | 2015 |
| Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 665 | 2015 |
| Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism SJ Mentch, M Mehrmohamadi, L Huang, X Liu, D Gupta, D Mattocks, ... Cell metabolism 22 (5), 861-873, 2015 | 583 | 2015 |
| T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 406 | 2019 |
| Metabolomics: a primer X Liu, JW Locasale Trends in biochemical sciences 42 (4), 274-284, 2017 | 405 | 2017 |
| Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells W Yan, X Wu, W Zhou, MY Fong, M Cao, J Liu, X Liu, CH Chen, O Fadare, ... Nature cell biology 20 (5), 597-609, 2018 | 340 | 2018 |
| Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation M Pan, MA Reid, XH Lowman, RP Kulkarni, TQ Tran, X Liu, Y Yang, ... Nature cell biology 18 (10), 1090-1101, 2016 | 329 | 2016 |
| Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step AA Shestov, X Liu, Z Ser, AA Cluntun, YP Hung, L Huang, D Kim, A Le, ... elife 3, e03342, 2014 | 318 | 2014 |
| Acetate production from glucose and coupling to mitochondrial metabolism in mammals X Liu, DE Cooper, AA Cluntun, MO Warmoes, S Zhao, MA Reid, J Liu, ... Cell 175 (2), 502-513. e13, 2018 | 300 | 2018 |
| Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function S Sadhukhan, X Liu, D Ryu, OD Nelson, JA Stupinski, Z Li, W Chen, ... Proceedings of the National Academy of Sciences 113 (16), 4320-4325, 2016 | 277 | 2016 |
| Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis M Curtis, HA Kenny, B Ashcroft, A Mukherjee, A Johnson, Y Zhang, ... Cell metabolism 29 (1), 141-155. e9, 2019 | 236 | 2019 |
| TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys H Liu, Y Chen, Y Niu, K Zhang, Y Kang, W Ge, X Liu, E Zhao, C Wang, ... Cell stem cell 14 (3), 323-328, 2014 | 236 | 2014 |
| Metformin targets central carbon metabolism and reveals mitochondrial requirements in human cancers X Liu, IL Romero, LM Litchfield, E Lengyel, JW Locasale Cell metabolism 24 (5), 728-739, 2016 | 229 | 2016 |
| Paracrine Wnt5a-β-catenin signaling triggers a metabolic program that drives dendritic cell tolerization F Zhao, C Xiao, KS Evans, T Theivanthiran, N DeVito, A Holtzhausen, ... Immunity 48 (1), 147-160. e7, 2018 | 212 | 2018 |
| The metabolic co-regulator PGC1α suppresses prostate cancer metastasis V Torrano, L Valcarcel-Jimenez, AR Cortazar, X Liu, J Urosevic, ... Nature cell biology 18 (6), 645-656, 2016 | 206 | 2016 |
| Modeling Rett syndrome using TALEN-edited MECP2 mutant cynomolgus monkeys Y Chen, J Yu, Y Niu, D Qin, H Liu, G Li, Y Hu, J Wang, Y Lu, Y Kang, ... Cell 169 (5), 945-955. e10, 2017 | 203 | 2017 |
| Development and quantitative evaluation of a high-resolution metabolomics technology X Liu, Z Ser, JW Locasale Analytical chemistry 86 (4), 2175-2184, 2014 | 195 | 2014 |
| A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product MV Liberti, Z Dai, SE Wardell, JA Baccile, X Liu, X Gao, R Baldi, ... Cell metabolism 26 (4), 648-659. e8, 2017 | 193 | 2017 |
| Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival S Sun, G Shi, X Han, AB Francisco, Y Ji, N Mendonça, X Liu, JW Locasale, ... Proceedings of the National Academy of Sciences 111 (5), E582-E591, 2014 | 181 | 2014 |
| Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 172 | 2017 |
