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Benjamin H. Lok
Benjamin H. Lok
Clinician-Scientist, Princess Margaret Cancer Centre
Dirección de correo verificada de rmp.uhn.ca
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Unravelling the biology of SCLC: implications for therapy
JK Sabari, BH Lok, JH Laird, JT Poirier, CM Rudin
Nature reviews Clinical oncology 14 (9), 549-561, 2017
4152017
Chemosensitive relapse in small cell lung cancer proceeds through an EZH2-SLFN11 axis
EE Gardner, BH Lok, VE Schneeberger, P Desmeules, LA Miles, ...
Cancer cell 31 (2), 286-299, 2017
4092017
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer
BH Lok, EE Gardner, VE Schneeberger, A Ni, P Desmeules, N Rekhtman, ...
Clinical Cancer Research 23 (2), 523-535, 2017
2902017
RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
BH Lok, AC Carley, B Tchang, SN Powell
Oncogene 32 (30), 3552-3558, 2013
2392013
New approaches to SCLC therapy: from the laboratory to the clinic
JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ...
Journal of Thoracic Oncology 15 (4), 520-540, 2020
1452020
Molecular pathways: understanding the role of Rad52 in homologous recombination for therapeutic advancement
BH Lok, SN Powell
Clinical cancer research 18 (23), 6400-6406, 2012
1412012
Binary pan-cancer classes with distinct vulnerabilities defined by pro-or anti-cancer YAP/TEAD activity
JD Pearson, K Huang, M Pacal, SR McCurdy, S Lu, A Aubry, T Yu, ...
Cancer Cell 39 (8), 1115-1134. e12, 2021
1002021
Target engagement imaging of PARP inhibitors in small-cell lung cancer
B Carney, S Kossatz, BH Lok, V Schneeberger, KK Gangangari, ...
Nature communications 9 (1), 176, 2018
912018
Palliative head and neck radiotherapy with the RTOG 8502 regimen for incurable primary or metastatic cancers
BH Lok, G Jiang, S Gutiontov, RM Lanning, S Sridhara, EJ Sherman, ...
Oral oncology 51 (10), 957-962, 2015
882015
Intensity-modulated radiation therapy in oropharyngeal carcinoma: effect of tumor volume on clinical outcomes
BH Lok, J Setton, N Caria, J Romanyshyn, SL Wolden, MJ Zelefsky, ...
International Journal of Radiation Oncology* Biology* Physics 82 (5), 1851-1857, 2012
802012
Talazoparib is a potent radiosensitizer in small cell lung cancer cell lines and xenografts
JH Laird, BH Lok, J Ma, A Bell, E de Stanchina, JT Poirier, CM Rudin
Clinical Cancer Research 24 (20), 5143-5152, 2018
752018
Challenges and opportunities in primary CNS lymphoma: A systematic review
MN Kerbauy, FY Moraes, BH Lok, J Ma, LN Kerbauy, DE Spratt, ...
Radiotherapy and Oncology 122 (3), 352-361, 2017
552017
Outcomes of multimodal therapy in a large series of patients with anaplastic thyroid cancer
D Fan, J Ma, AC Bell, AH Groen, KS Olsen, BH Lok, JE Leeman, ...
Cancer 126 (2), 444-452, 2020
502020
Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies
J Ma, JH Laird, KW Chau, MR Chelius, BH Lok, J Yahalom
Cancer Medicine 8 (1), 58-66, 2019
482019
Factors influencing the utilization of prophylactic cranial irradiation in patients with limited-stage small cell lung cancer
BH Lok, J Ma, A Foster, CA Perez, W Shi, Z Zhang, BT Li, CM Rudin, ...
Advances in Radiation Oncology 2 (4), 548-554, 2017
482017
Impact of laparoscopic adjustable gastric banding on pregnancy, maternal weight, and neonatal health
AM Carelli, CJ Ren, HA Youn, EB Friedman, AE Finger, BH Lok, ...
Obesity surgery 21, 1552-1558, 2011
442011
Long‐term regional control in the observed neck following definitive chemoradiation for node‐positive oropharyngeal squamous cell cancer
A Goenka, LGT Morris, SS Rao, SL Wolden, RJ Wong, DH Kraus, N Ohri, ...
International journal of cancer 133 (5), 1214-1221, 2013
432013
Intensity‐modulated radiotherapy for head and neck surgeons
SI Gutiontov, EJ Shin, B Lok, NY Lee, R Cabanillas
Head & neck 38 (S1), E2368-E2373, 2016
412016
The relative prognostic utility of standardized uptake value, gross tumor volume, and metabolic tumor volume in oropharyngeal cancer patients treated with platinum based …
PB Romesser, R Lim, DE Spratt, J Setton, N Riaz, B Lok, S Rao, ...
Oral oncology 50 (9), 802-808, 2014
412014
Stereotactic radiosurgery versus whole brain radiotherapy in patients with intracranial metastatic disease and small-cell lung cancer: a systematic review and meta-analysis
K Gaebe, AY Li, A Park, A Parmar, BH Lok, A Sahgal, KKW Chan, ...
The Lancet Oncology 23 (7), 931-939, 2022
382022
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Artículos 1–20