| Regulation of cell death protease caspase-9 by phosphorylation MH Cardone, N Roy, HR Stennicke, GS Salvesen, TF Franke, ... Science 282 (5392), 1318-1321, 1998 | 4290 | 1998 |
| Regulation of endothelium-derived nitric oxide production by the protein kinase Akt D Fulton, JP Gratton, TJ McCabe, J Fontana, Y Fujio, K Walsh, TF Franke, ... Nature 399 (6736), 597-601, 1999 | 3152 | 1999 |
| Regulation of neuronal survival by the serine-threonine protein kinase Akt H Dudek, SR Datta, TF Franke, MJ Birnbaum, R Yao, GM Cooper, ... Science 275 (5300), 661-665, 1997 | 3087 | 1997 |
| The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase TF Franke, SI Yang, TO Chan, K Datta, A Kazlauskas, DK Morrison, ... Cell 81 (5), 727-736, 1995 | 2626 | 1995 |
| PI3K: downstream AKTion blocks apoptosis TF Franke, DR Kaplan, LC Cantley Cell 88 (4), 435-437, 1997 | 2174 | 1997 |
| Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate TF Franke, DR Kaplan, LC Cantley, A Toker Science 275 (5300), 665-668, 1997 | 1969 | 1997 |
| Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD HG Wang, N Pathan, IM Ethell, S Krajewski, Y Yamaguchi, F Shibasaki, ... Science 284 (5412), 339-343, 1999 | 1518 | 1999 |
| PI3K/Akt and apoptosis: size matters TF Franke, CP Hornik, L Segev, GA Shostak, C Sugimoto Oncogene 22 (56), 8983-8998, 2003 | 1426 | 2003 |
| AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. JQ Cheng, AK Godwin, A Bellacosa, T Taguchi, TF Franke, TC Hamilton, ... Proceedings of the National Academy of Sciences 89 (19), 9267-9271, 1992 | 1006 | 1992 |
| Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1 AH Kim, GUS Khursigara, X Sun, TF Franke, MV Chao Molecular and cellular biology 21 (3), 893-901, 2001 | 938 | 2001 |
| PI3K/Akt: getting it right matters TF Franke Oncogene 27 (50), 6473-6488, 2008 | 895 | 2008 |
| Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo T Matsui, J Tao, F del Monte, KH Lee, L Li, M Picard, TL Force, TF Franke, ... Circulation 104 (3), 330-335, 2001 | 837 | 2001 |
| Akt/protein kinase B promotes organ growth in transgenic mice T Shioi, JR McMullen, PM Kang, PS Douglas, T Obata, TF Franke, ... Molecular and cellular biology 22 (8), 2799-2809, 2002 | 626 | 2002 |
| Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival X Wang, KD McCullough, TF Franke, NJ Holbrook Journal of Biological Chemistry 275 (19), 14624-14631, 2000 | 545 | 2000 |
| Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro T Matsui, L Li, F del Monte, Y Fukui, TF Franke, RJ Hajjar, A Rosenzweig Circulation 100 (23), 2373-2379, 1999 | 461 | 1999 |
| Interleukin 3-dependent survival by the Akt protein kinase Z Songyang, D Baltimore, LC Cantley, DR Kaplan, TF Franke Proceedings of the National Academy of Sciences 94 (21), 11345-11350, 1997 | 447 | 1997 |
| Opposite effects of fear conditioning and extinction on dendritic spine remodelling CSW Lai, TF Franke, WB Gan Nature 483 (7387), 87-91, 2012 | 431 | 2012 |
| A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I MB Martin, TF Franke, GE Stoica, P Chambon, BS Katzenellenbogen, ... Endocrinology 141 (12), 4503-4511, 2000 | 334 | 2000 |
| Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling SG Lee, ZZ Su, L Emdad, D Sarkar, TF Franke, PB Fisher Oncogene 27 (8), 1114-1121, 2008 | 276 | 2008 |
| Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications. A Bellacosa, TF Franke, ME Gonzalez-Portal, K Datta, T Taguchi, ... Oncogene 8 (3), 745-754, 1993 | 254 | 1993 |
