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Aria Vaishnavi, PhD
Aria Vaishnavi, PhD
Assistant Professor, University of Texas MD Anderson Cancer Center
Dirección de correo verificada de mdanderson.org
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Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
A Vaishnavi, M Capelletti, AT Le, S Kako, M Butaney, D Ercan, S Mahale, ...
Nature medicine 19 (11), 1469-1472, 2013
6872013
TRKing down an old oncogene in a new era of targeted therapy
A Vaishnavi, AT Le, RC Doebele
Cancer discovery 5 (1), 25-34, 2015
6402015
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
RC Doebele, LE Davis, A Vaishnavi, AT Le, A Estrada-Bernal, S Keysar, ...
Cancer discovery 5 (10), 1049-1057, 2015
412*2015
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK–positive lung cancer
G Hrustanovic, V Olivas, E Pazarentzos, A Tulpule, S Asthana, ...
Nature medicine 21 (9), 1038-1047, 2015
2942015
Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer
KD Davies, S Mahale, DP Astling, DL Aisner, AT Le, TK Hinz, A Vaishnavi, ...
PloS one 8 (12), e82236, 2013
1622013
EGFR mediates responses to small-molecule drugs targeting oncogenic fusion kinases
A Vaishnavi, L Schubert, U Rix, LA Marek, AT Le, SB Keysar, ...
Cancer research 77 (13), 3551-3563, 2017
772017
TRKing down an old oncogene in a new era of targeted therapy. Cancer Discov. 2015; 5: 25–34. doi: 10.1158/2159-8290
A Vaishnavi, AT Le, RC Doebele
CD-14-0765.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
76
Organ-specific gene expression: the bHLH protein Sage provides tissue specificity to Drosophila FoxA
RM Fox, A Vaishnavi, R Maruyama, DJ Andrew
Development 140 (10), 2160-2171, 2013
402013
NTRK1 gene fusions as a novel oncogene target in lung cancer.
RC Doebele, A Vaishnavi, M Capelletti, AT Le, S Kako, M Butaney, ...
Journal of Clinical Oncology 31 (15_suppl), 8023-8023, 2013
212013
Inhibition of MEK1/2 forestalls the onset of acquired resistance to entrectinib in multiple models of NTRK1-driven cancer
A Vaishnavi, MT Scherzer, CG Kinsey, GL Parkman, A Truong, P Ghazi, ...
Cell reports 32 (5), 2020
172020
TRKing down an old oncogene in a new era of targeted therapy. Cancer Discov. 2015; 5: 25–34
A Vaishnavi, AT Le, RC Doebele
PUBMED, 0
10
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
A Vaishnavi, J Juan, M Jacob, C Stehn, EE Gardner, MT Scherzer, ...
Cancer research 82 (22), 4261-4273, 2022
82022
Analysis of NTRK1 gene fusion incidence in an unselected cohort of non-small cell lung cancer patients.
RC Doebele, S Kako, AT Le, M da Costa Silva, A Vaishnavi, L Toschi, ...
Journal of Clinical Oncology 32 (15_suppl), 8048-8048, 2014
42014
Abstract A29: The CUTO panel of patient-derived NSCLC cell lines reveals unique molecular characteristics and responses to targeted therapies
AT Le, A Estrada-Bernal, L Schubert, A Doak, N Chen, K Davies, ...
Clinical Cancer Research 24 (17_Supplement), A29-A29, 2018
22018
Adaptive Survival Signaling in Oncogenic Fusion Kinase Addicted NSCLC
A Vaishnavi, SB Keysar, AT Le, DL Aisner, L Heasley, A Jimeno, ...
JOURNAL OF THORACIC ONCOLOGY 10 (9), S214-S214, 2015
12015
BRAFV600E-mutant metastatic NSCLC: disease overview and treatment landscape
D Planchard, RE Sanborn, MV Negrao, A Vaishnavi, EF Smit
NPJ Precision Oncology 8 (1), 90, 2024
2024
Preclinical Modeling of Pathway-Targeted Therapy of Human Lung Cancer in the Mouse
A Vaishnavi, CG Kinsey, M McMahon
Cold Spring Harbor Perspectives in Medicine 14 (1), a041385, 2024
2024
Transposon Mutagenesis Reveals RBMS3 as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis
A Vaishnavi, J Juan, MT Scherzer, JE VanVeen, C Stehn, CS Hackett, ...
bioRxiv, 2022.02. 28.482366, 2022
2022
Combined TRKA and MEK1/2 Inhibition Forestalls the Onset of Acquired Resistance in a New Preclinical Model of NTRK1+ Pancreatic Cancer
A Vaishnavi, MT Scherzer, C Kinsey, I Garrido-Laguna, M McMahon
Cancer Research 80 (16_Supplement), 3769-3769, 2020
2020
The CUTO panel of patient-derived NSCLC cell lines reveals unique molecular characteristics and responses to targeted therapies
AT Le, A Estrada-Bernal, L Schubert, A Doak, N Chen, K Davies, ...
CLINICAL CANCER RESEARCH 24 (17), 2018
2018
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