Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 769 | 2018 |
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils C Engblom, C Pfirschke, R Zilionis, J Da Silva Martins, SA Bos, G Courties, ... Science 358 (6367), eaal5081, 2017 | 318 | 2017 |
Chromothriptic cure of WHIM syndrome DH McDermott, JL Gao, Q Liu, M Siwicki, C Martens, P Jacobs, D Velez, ... Cell 160 (4), 686-699, 2015 | 178 | 2015 |
A neutrophil response linked to tumor control in immunotherapy J Gungabeesoon, NA Gort-Freitas, M Kiss, E Bolli, M Messemaker, ... Cell 186 (7), 1448-1464. e20, 2023 | 80 | 2023 |
Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils C Pfirschke, C Engblom, J Gungabeesoon, Y Lin, S Rickelt, R Zilionis, ... Cell reports 32 (12), 2020 | 79 | 2020 |
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy M Siwicki, NA Gort-Freitas, M Messemaker, R Bill, J Gungabeesoon, ... Science immunology 6 (61), eabi7083, 2021 | 56 | 2021 |
Tumor microenvironment: no effector T cells without dendritic cells C Pfirschke, M Siwicki, HW Liao, MJ Pittet Cancer Cell 31 (5), 614-615, 2017 | 51 | 2017 |
Macrophage-targeted therapy unlocks antitumoral cross-talk between IFNγ-secreting lymphocytes and IL12-producing dendritic cells C Pfirschke, R Zilionis, C Engblom, M Messemaker, AE Zou, S Rickelt, ... Cancer immunology research 10 (1), 40-55, 2022 | 28 | 2022 |
Gal3 links inflammation and insulin resistance M Siwicki, C Engblom, MJ Pittet Cell metabolism 24 (5), 655-656, 2016 | 27 | 2016 |
Versatile neutrophil functions in cancer M Siwicki, MJ Pittet Seminars in Immunology 57, 101538, 2021 | 24 | 2021 |
LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects HW Liao, C Garris, C Pfirschke, S Rickelt, S Arlauckas, M Siwicki, ... Cell Stress 3 (11), 348, 2019 | 23 | 2019 |
Cxcr4-haploinsufficient bone marrow transplantation corrects leukopenia in an unconditioned WHIM syndrome model JL Gao, E Yim, M Siwicki, A Yang, Q Liu, A Azani, A Owusu-Ansah, ... The Journal of Clinical Investigation 128 (8), 3312-3318, 2018 | 14 | 2018 |
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 55 (9), 1749, 2022 | 12 | 2022 |
Neutrophils in host defense, healing, and hypersensitivity: Dynamic cells within a dynamic host M Siwicki, P Kubes Journal of Allergy and Clinical Immunology 151 (3), 634-655, 2023 | 10 | 2023 |
Low-level Cxcr4-haploinsufficient HSC engraftment is sufficient to correct leukopenia in WHIM syndrome mice JL Gao, A Owusu-Ansah, A Paun, K Beacht, E Yim, M Siwicki, A Yang, ... JCI insight 4 (24), 2019 | 5 | 2019 |
Leukocyte chemotactic receptor Fpr1 protects against aging-related posterior subcapsular cataract formation JL Gao, JD Weaver, J Tuo, LQ Wang, M Siwicki, D Despres, M Lizak, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 3 | 2021 |
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-gamma and IL-12 (vol 49, 1148. e1, 2018) CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 55 (9), 1749-1749, 2022 | 2 | 2022 |
1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer R Jain, N Talele, H Kumra, IG Dos Santos, S Roberge, W Ho, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
Abstract B025: IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer NP Talele, H Kumra, IL Gomes-Santos, S Roberge, WW Ho, P Andersson, ... Cancer Research 84 (2_Supplement), B025-B025, 2024 | | 2024 |
Reducing CXCR4 expression and/or function to enhance engraftment of hematopoietic stem cells J Gao, PM Murphy, DH McDermott, M Siwicki, HL Malech, J Liu, P Jacobs US Patent 11,278,572, 2022 | | 2022 |