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Julian Knight
Julian Knight
Professor of Genomic Medicine, University of Oxford
Dirección de correo verificada de well.ox.ac.uk - Página principal
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021
52162021
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ...
The Lancet 396 (10249), 467-478, 2020
27342020
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
18692013
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ...
The Lancet 396 (10267), 1979-1993, 2020
16382020
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10277), 881-891, 2021
13082021
Genetic mechanisms of critical illness in COVID-19
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
12812021
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong, W Dejnirattisai, ...
Nature immunology 21 (11), 1336-1345, 2020
11752020
Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera
D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer, HM Ginn, Y Zhao, ...
Cell 184 (9), 2348-2361. e6, 2021
11072021
A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution
SV Ramagopalan, A Heger, AJ Berlanga, NJ Maugeri, MR Lincoln, ...
Genome research 20 (10), 1352-1360, 2010
10952010
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DS Cunninghame Graham, CL Pinder, ...
Nature genetics 47 (12), 1457-1464, 2015
8182015
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 1246949, 2014
8042014
Major histocompatibility complex genomics and human disease
J Trowsdale, JC Knight
Annual review of genomics and human genetics 14, 301-323, 2013
7382013
Reduced neutralization of SARS-CoV-2 B. 1.617 by vaccine and convalescent serum
C Liu, HM Ginn, W Dejnirattisai, P Supasa, B Wang, A Tuekprakhon, ...
Cell 184 (16), 4220-4236. e13, 2021
7252021
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7002021
Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D
SV Ramagopalan, NJ Maugeri, L Handunnetthi, MR Lincoln, SM Orton, ...
PLoS genetics 5 (2), e1000369, 2009
6862009
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
6752021
Antibody evasion by the P. 1 strain of SARS-CoV-2
W Dejnirattisai, D Zhou, P Supasa, C Liu, AJ Mentzer, HM Ginn, Y Zhao, ...
Cell 184 (11), 2939-2954. e9, 2021
6452021
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
JC Knight, I Udalova, AVS Hill, BM Greenwood, N Peshu, K Marsh, ...
Nature genetics 22 (2), 145-150, 1999
6221999
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
EE Davenport, KL Burnham, J Radhakrishnan, P Humburg, P Hutton, ...
The Lancet Respiratory Medicine 4 (4), 259-271, 2016
6022016
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
5612012
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Artículos 1–20