| Novel tacrine− melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties MI Rodríguez-Franco, MI Fernández-Bachiller, C Pérez, ... Journal of Medicinal Chemistry 49 (2), 459-462, 2006 | 329 | 2006 |
| Novel tacrine− 8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer’s disease, with neuroprotective, cholinergic, antioxidant, and copper … MI Fernández-Bachiller, C Pérez, GC González-Munoz, S Conde, ... Journal of medicinal chemistry 53 (13), 4927-4937, 2010 | 318 | 2010 |
| New Tacrine–4-Oxo-4H-chromene Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Cholinergic, Antioxidant, and β-Amyloid … MI Fernández-Bachiller, C Pérez, L Monjas, J Rademann, ... Journal of medicinal chemistry 55 (3), 1303-1317, 2012 | 297 | 2012 |
| Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds P Camps, X Formosa, C Galdeano, D Munoz-Torrero, L Ramirez, ... Journal of medicinal chemistry 52 (17), 5365-5379, 2009 | 231 | 2009 |
| Tacrine–melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties MI Fernández‐Bachiller, C Pérez, NE Campillo, JA Páez, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 828-841, 2009 | 201 | 2009 |
| Tacripyrines, the first tacrine− dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer’s disease J Marco-Contelles, R León, C De Los Ríos, A Samadi, M Bartolini, ... Journal of medicinal chemistry 52 (9), 2724-2732, 2009 | 174 | 2009 |
| The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro JA Morales-García, M De la Fuente Revenga, S Alonso-Gil, ... Scientific reports 7 (1), 5309, 2017 | 168 | 2017 |
| Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer’s disease MP Arce, MI Rodríguez-Franco, GC Gonzalez-Munoz, C Pérez, B Lopez, ... Journal of medicinal chemistry 52 (22), 7249-7257, 2009 | 146 | 2009 |
| Huprine–tacrine heterodimers as anti-amyloidogenic compounds of potential interest against Alzheimer’s and prion diseases C Galdeano, E Viayna, I Sola, X Formosa, P Camps, A Badia, MV Clos, ... Journal of medicinal chemistry 55 (2), 661-669, 2012 | 120 | 2012 |
| New Melatonin–N,N-Dibenzyl(N-methyl)amine Hybrids: Potent Neurogenic Agents with Antioxidant, Cholinergic, and Neuroprotective Properties as Innovative … B Lopez-Iglesias, C Perez, JA Morales-García, S Alonso-Gil, ... Journal of medicinal chemistry 57 (9), 3773-3785, 2014 | 103 | 2014 |
| Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer’s disease by hybridization of curcumin and … JE Chojnacki, K Liu, X Yan, S Toldo, T Selden, M Estrada, ... ACS chemical neuroscience 5 (8), 690-699, 2014 | 88 | 2014 |
| Novel Tacrine‐Grafted Ugi Adducts as Multipotent Anti‐Alzheimer Drugs: A Synthetic Renewal in Tacrine–Ferulic Acid Hybrids M Benchekroun, M Bartolini, J Egea, A Romero, E Soriano, M Pudlo, ... ChemMedChem 10 (3), 523-539, 2015 | 81 | 2015 |
| Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9, 10, 11, 12-tetrahydro-7H-benzo [7, 8] chromeno [2, 3-b] quinolin-8-amines as potential drugs for … E Maalej, F Chabchoub, MJ Oset-Gasque, M Esquivias-Pérez, ... European journal of medicinal chemistry 54, 750-763, 2012 | 78 | 2012 |
| Novel Huprine Derivatives with Inhibitory Activity toward β‐Amyloid Aggregation and Formation as Disease‐Modifying Anti‐Alzheimer Drug Candidates E Viayna, T Gómez, C Galdeano, L Ramírez, M Ratia, A Badia, MV Clos, ... ChemMedChem 5 (11), 1855-1870, 2010 | 75 | 2010 |
| A new tacrine–melatonin hybrid reduces amyloid burden and behavioral deficits in a mouse model of Alzheimer’s disease C Spuch, D Antequera, M Isabel Fernandez-Bachiller, ... Neurotoxicity research 17, 421-431, 2010 | 75 | 2010 |
| N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a New Cholinesterase and Monoamine Oxidase … OM Bautista-Aguilera, A Samadi, M Chioua, K Nikolic, S Filipic, D Agbaba, ... Journal of medicinal chemistry 57 (24), 10455-10463, 2014 | 70 | 2014 |
| α-Aryl-N-alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain … M Chioua, D Sucunza, E Soriano, D Hadjipavlou-Litina, A Alcázar, ... Journal of medicinal chemistry 55 (1), 153-168, 2012 | 69 | 2012 |
| Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: effect against amyloid-β-induced neurotoxicity D Silva, M Chioua, A Samadi, P Agostinho, P Garcao, R Lajarín-Cuesta, ... ACS Chemical Neuroscience 4 (4), 547-565, 2013 | 64 | 2013 |
| Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling A Samadi, M Estrada, C Pérez, MI Rodríguez-Franco, I Iriepa, I Moraleda, ... European journal of medicinal chemistry 57, 296-301, 2012 | 64 | 2012 |
| Design and synthesis of N-benzylpiperidine–purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase MI Rodríguez-Franco, MI Fernández-Bachiller, C Pérez, A Castro, ... Bioorganic & medicinal chemistry 13 (24), 6795-6802, 2005 | 63 | 2005 |
Manuela G. Lopez (Manuela García L...Universidad Autonoma de MadridVerified email at uam.es
