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Morgan E Milton
Morgan E Milton
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The structure of the biofilm-controlling response regulator BfmR from Acinetobacter baumannii reveals details of its DNA-binding mechanism
GL Draughn, ME Milton, EA Feldmann, BG Bobay, BM Roth, AL Olson, ...
Journal of molecular biology 430 (6), 806-821, 2018
482018
Re-sensitizing multidrug resistant bacteria to antibiotics by targeting bacterial response regulators: characterization and comparison of interactions between 2-aminoimidazoles …
ME Milton, BM Minrovic, DL Harris, B Kang, D Jung, CP Lewis, ...
Frontiers in Molecular Biosciences 5, 15, 2018
322018
The solution structures and interaction of SinR and SinI: elucidating the mechanism of action of the master regulator switch for biofilm formation in Bacillus subtilis
ME Milton, GL Draughn, BG Bobay, SD Stowe, AL Olson, EA Feldmann, ...
Journal of molecular biology 432 (2), 343-357, 2020
312020
Replication and maintenance of the Plasmodium falciparum apicoplast genome
ME Milton, SW Nelson
Molecular and biochemical parasitology 208 (2), 56-64, 2016
262016
Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2‐aminoimidazole‐based compounds
ME Milton, CL Allen, EA Feldmann, BG Bobay, DK Jung, MD Stephens, ...
Molecular microbiology 106 (2), 223-235, 2017
232017
Acinetobacter baumannii regulates its stress responses via the BfmRS two-component regulatory system
S Palethorpe, JM Farrow III, G Wells, ME Milton, LA Actis, J Cavanagh, ...
Journal of bacteriology 204 (2), e00494-21, 2022
212022
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum
ME Miller, EE Parrott, R Singh, SW Nelson
Journal of biomolecular screening 19 (6), 966-972, 2014
172014
Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production
SN Dean, ME Milton, J Cavanagh, ML Van Hoek
Frontiers in Cellular and Infection Microbiology 10, 82, 2020
132020
Crystal structure of the apicoplast DNA polymerase from Plasmodium falciparum: the first look at a plastidic A-family DNA polymerase
ME Milton, JY Choe, RB Honzatko, SW Nelson
Journal of molecular biology 428 (20), 3920-3934, 2016
122016
Structure of the Acinetobacter baumannii PmrA receiver domain and insights into clinical mutants affecting DNA binding and promoting colistin resistance
S Palethorpe, ME Milton, EC Pesci, J Cavanagh
Journal of Biochemistry 170 (6), 787-800, 2021
62021
Crystallization and preliminary X-ray analysis of the Plasmodium falciparum apicoplast DNA polymerase
ME Milton, J Choe, RB Honzatko, SW Nelson
Acta Crystallographica Section F: Structural Biology Communications 71 (3 …, 2015
42015
The biofilm regulatory network from Bacillus subtilis: A structure-function analysis
ME Milton, J Cavanagh
Journal of Molecular Biology 435 (3), 167923, 2023
32023
Computational and cellular exploration of the protein-protein interaction between Vibrio fischeri STAS domain protein SypA and serine kinase SypE
ME Milton, KL Visick
Communicative & Integrative Biology 16 (1), 2203626, 2023
12023
Inhibition and Dispersion of Biofilms: Targeting Bacterial Response Regulators to Resensitize Multidrug Resistant Bacteria to Antibiotics
ME Milton, GL Draughn, EA Feldmann, RJ Thompson, D Jung, B Kang, ...
The FASEB Journal 31 (1_supplement), 939.15-939.15, 2017
12017
2-Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria
TN Zeczycki, ME Milton, D Jung, RJ Thompson, FE Jaimes, AD Hondros, ...
Biochemistry 61 (24), 2948-2960, 2022
2022
Filling in the gaps for the master regulator of biofilm formation in Bacillus subtilis: A structural and biochemical look at SinR and SinI
ME Milton, GL Draughn, BG Bobay, SD Stowe, AL Olson, EA Feldmann, ...
The FASEB Journal 33 (S1), 631.30-631.30, 2019
2019
Resensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators
ME Milton, BM Minrovic, DL Harris, GL Draughn, B Kang, D Jung, ...
The FASEB Journal 32 (1_supplement), 810.5-810.5, 2018
2018
Exploration of the Atypical Regions of the Plasmodium falciparum Apicoplast DNA Polymerase and Their Potential Role in Antimalarial Drug Discovery
ME Milton, RB Honzatko, SW Nelson
The FASEB Journal 30 (1_supplement), 578.2-578.2, 2016
2016
Structure and function of the Plasmodium falciparum apicoplast DNA polymerase: the first look at an" atypical" A-family polymerase and its potential in antimalarial drug discovery
ME Milton
Iowa State Univeristy, 2016
2016
Crystal Structure of the Plasmodium falciparum Apicoplast DNA Polymerase
M Milton, R Honzatko, S Nelson
The FASEB Journal 29 (1_supplement), 560.4, 2015
2015
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