| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1573 | 2015 |
| Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis FF Vajdos, CW Adams, TN Breece, LG Presta, AM de Vos, SS Sidhu Journal of molecular biology 320 (2), 415-428, 2002 | 835 | 2002 |
| Beyond natural antibodies: the power of in vitro display technologies ARM Bradbury, S Sidhu, S Dübel, J McCafferty Nature biotechnology 29 (3), 245-254, 2011 | 654 | 2011 |
| Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies K Newton, ML Matsumoto, IE Wertz, DS Kirkpatrick, JR Lill, J Tan, ... Cell 134 (4), 668-678, 2008 | 653 | 2008 |
| [21] Phage display for selection of novel binding peptides SS Sidhu, HB Lowman, BC Cunningham, JA Wells Methods in enzymology 328, 333-IN5, 2000 | 639 | 2000 |
| A specificity map for the PDZ domain family R Tonikian, Y Zhang, SL Sazinsky, B Currell, JH Yeh, B Reva, HA Held, ... PLoS biology 6 (9), e239, 2008 | 563 | 2008 |
| Visualization of arrestin recruitment by a G-protein-coupled receptor AK Shukla, GH Westfield, K Xiao, RI Reis, LY Huang, P Tripathi-Shukla, ... Nature 512 (7513), 218-222, 2014 | 518 | 2014 |
| Rapid mapping of protein functional epitopes by combinatorial alanine scanning GA Weiss, CK Watanabe, A Zhong, A Goddard, SS Sidhu Proceedings of the National Academy of Sciences 97 (16), 8950-8954, 2000 | 463 | 2000 |
| Phage display in pharmaceutical biotechnology SS Sidhu Current opinion in biotechnology 11 (6), 610-616, 2000 | 461 | 2000 |
| Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition FA Fellouse, C Wiesmann, SS Sidhu Proceedings of the National Academy of Sciences 101 (34), 12467-12472, 2004 | 459 | 2004 |
| High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries FA Fellouse, K Esaki, S Birtalan, D Raptis, VJ Cancasci, A Koide, ... Journal of molecular biology 373 (4), 924-940, 2007 | 449 | 2007 |
| High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold CV Lee, WC Liang, MS Dennis, C Eigenbrot, SS Sidhu, G Fuh Journal of molecular biology 340 (5), 1073-1093, 2004 | 430 | 2004 |
| Engineering M13 for phage display SS Sidhu Biomolecular engineering 18 (2), 57-63, 2001 | 375 | 2001 |
| Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2 JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ... Cell host & microbe 28 (3), 475-485. e5, 2020 | 373 | 2020 |
| Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma MA Qazi, P Vora, C Venugopal, SS Sidhu, J Moffat, C Swanton, SK Singh Annals of Oncology 28 (7), 1448-1456, 2017 | 359 | 2017 |
| Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions SS Sidhu, B Li, Y Chen, FA Fellouse, C Eigenbrot, G Fuh Journal of molecular biology 338 (2), 299-310, 2004 | 335 | 2004 |
| Synthetic antibody phage libraries G Fuh, SS Sidhu US Patent 7,985,840, 2011 | 327 | 2011 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 314 | 2013 |
| Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017 | 297 | 2017 |
| Variable domain library and uses CJ Bond, S Sidhu US Patent 7,785,903, 2010 | 294 | 2010 |
