| PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides: effect of insulin D Sbrissa, OC Ikonomov, A Shisheva Journal of Biological Chemistry 274 (31), 21589-21597, 1999 | 307 | 1999 |
| Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve OC Ikonomov, D Sbrissa, A Shisheva Journal of Biological Chemistry 276 (28), 26141-26147, 2001 | 274 | 2001 |
| PIKfyve: Partners, significance, debates and paradoxes A Shisheva Cell biology international 32 (6), 591-604, 2008 | 210 | 2008 |
| Core protein machinery for mammalian phosphatidylinositol 3, 5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport: novel Sac phosphatase … D Sbrissa, OC Ikonomov, Z Fu, T Ijuin, J Gruenberg, T Takenawa, ... Journal of Biological Chemistry 282 (33), 23878-23891, 2007 | 208 | 2007 |
| Insulinlike effects of zinc ion in vitro and in vivo: preferential effects on desensitized adipocytes and induction of normoglycemia in streptozocin-induced rats A Shisheva, D Gefel, Y Shechter Diabetes 41 (8), 982-988, 1992 | 199 | 1992 |
| Molecular basis for the insulinomimetic effects of C-peptide G Grunberger, X Qiang, Z Li, ST Mathews, D Sbrissa, A Shisheva, ... Diabetologia 44, 1247-1257, 2001 | 198 | 2001 |
| Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3, 5-bisphosphate interaction K Tsujita, T Itoh, T Ijuin, A Yamamoto, A Shisheva, J Laporte, T Takenawa Journal of Biological Chemistry 279 (14), 13817-13824, 2004 | 171 | 2004 |
| Quercetin selectively inhibits insulin receptor function in vitro and the bioresponses of insulin and insulinomimetic agents in rat adipocytes A Shisheva, Y Shechter Biochemistry 31 (34), 8059-8063, 1992 | 169 | 1992 |
| The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve−/− embryos but normality of PIKfyve+/− mice OC Ikonomov, D Sbrissa, K Delvecchio, Y Xie, JP Jin, D Rappolee, ... Journal of Biological Chemistry 286 (15), 13404-13413, 2011 | 157 | 2011 |
| Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells D Sbrissa, OC Ikonomov, R Deeb, A Shisheva Journal of Biological Chemistry 277 (49), 47276-47284, 2002 | 156 | 2002 |
| Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3, 5-P2 production for endomembrane integrity OC Ikonomov, D Sbrissa, K Mlak, M Kanzaki, J Pessin, A Shisheva Journal of Biological Chemistry 277 (11), 9206-9211, 2002 | 143 | 2002 |
| Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve: binding specificity and role in PIKfyve endomembrane localization D Sbrissa, OC Ikonomov, A Shisheva Journal of Biological Chemistry 277 (8), 6073-6079, 2002 | 139 | 2002 |
| Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion OC Ikonomov, D Sbrissa, A Shisheva American Journal of Physiology-Cell Physiology 291 (2), C393-C404, 2006 | 130 | 2006 |
| PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis OC Ikonomov, D Sbrissa, M Foti, JL Carpentier, A Shisheva Molecular biology of the cell 14 (11), 4581-4591, 2003 | 129 | 2003 |
| Cloning, Characterization, and Expression of a Novel Zn2+-Binding FYVE Finger-Containing Phosphoinositide Kinase in Insulin-Sensitive Cells A Shisheva, D Sbrissa, O Ikonomov Molecular and Cellular Biology 19 (1), 623-634, 1999 | 129 | 1999 |
| Complementation Analysis in PtdInsPKinase-deficient Yeast Mutants Demonstrates ThatSchizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5 … RK McEwen, SK Dove, FT Cooke, GF Painter, AB Holmes, A Shisheva, ... Journal of Biological Chemistry 274 (48), 33905-33912, 1999 | 128 | 1999 |
| Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes. A Shisheva, Y Shechter Journal of Biological Chemistry 268 (9), 6463-6469, 1993 | 127 | 1993 |
| Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation D Sbrissa, OC Ikonomov, J Strakova, A Shisheva Endocrinology 145 (11), 4853-4865, 2004 | 124 | 2004 |
| PIKfyve: the road to PtdIns 5-P and PtdIns 3, 5-P2 A Shisheva Cell biology international 25 (12), 1201-1206, 2001 | 100 | 2001 |
| Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle A Shisheva, TC Südhof, MP Czech Molecular and cellular biology, 1994 | 100 | 1994 |
