The human body at cellular resolution: the NIH Human Biomolecular Atlas Program Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ... Nature 574 (7777), 187-192, 2019 | 384 | 2019 |
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells T Manzo, BM Prentice, KG Anderson, A Raman, A Schalck, GS Codreanu, ... Journal of Experimental Medicine 217 (8), 2020 | 175 | 2020 |
Advanced registration and analysis of MALDI imaging mass spectrometry measurements through autofluorescence microscopy NH Patterson, M Tuck, R Van de Plas, RM Caprioli Analytical chemistry 90 (21), 12395-12403, 2018 | 92 | 2018 |
Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies A Thomas, NH Patterson, MM Marcinkiewicz, A Lazaris, P Metrakos, ... Analytical chemistry 85 (5), 2860-2866, 2013 | 84 | 2013 |
Uncovering matrix effects on lipid analyses in MALDI imaging mass spectrometry experiments WJ Perry, NH Patterson, BM Prentice, EK Neumann, RM Caprioli, ... Journal of mass spectrometry 55 (4), e4491, 2020 | 67 | 2020 |
Monitoring time‐dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry NH Patterson, A Thomas, P Chaurand Journal of Mass spectrometry 49 (7), 622-627, 2014 | 62 | 2014 |
MicroLESA: integrating autofluorescence microscopy, in situ micro-digestions, and liquid extraction surface analysis for high spatial resolution targeted proteomic studies DJ Ryan, NH Patterson, NE Putnam, AD Wilde, A Weiss, WJ Perry, ... Analytical chemistry 91 (12), 7578-7585, 2019 | 59 | 2019 |
Combining salt doping and matrix sublimation for high spatial resolution MALDI imaging mass spectrometry of neutral lipids M Dufresne, NH Patterson, JL Norris, RM Caprioli Analytical chemistry 91 (20), 12928-12934, 2019 | 58 | 2019 |
Next generation histology-directed imaging mass spectrometry driven by autofluorescence microscopy NH Patterson, M Tuck, A Lewis, A Kaushansky, JL Norris, R Van de Plas, ... Analytical chemistry 90 (21), 12404-12413, 2018 | 57 | 2018 |
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review M Tuck, L Blanc, R Touti, NH Patterson, S Van Nuffel, S Villette, ... Analytical chemistry 93 (1), 445-477, 2020 | 56 | 2020 |
Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry M Dufresne, D Guneysu, NH Patterson, MM Marcinkiewicz, A Regina, ... Analytical and bioanalytical chemistry 409, 1425-1433, 2017 | 53 | 2017 |
Three‐dimensional imaging MS of lipids in atherosclerotic plaques: Open‐source methods for reconstruction and analysis NH Patterson, RJ Doonan, SS Daskalopoulou, M Dufresne, S Lenglet, ... Proteomics 16 (11-12), 1642-1651, 2016 | 52 | 2016 |
Assessment of pathological response to therapy using lipid mass spectrometry imaging NH Patterson, B Alabdulkarim, A Lazaris, A Thomas, MM Marcinkiewicz, ... Scientific reports 6 (1), 36814, 2016 | 48 | 2016 |
Orthogonal organic and aqueous‐based washes of tissue sections to enhance protein sensitivity by MALDI imaging mass spectrometry A Thomas, NH Patterson, J Laveaux Charbonneau, P Chaurand Journal of Mass Spectrometry 48 (1), 42-48, 2013 | 47 | 2013 |
A recommended and verified procedure for in situ tryptic digestion of formalin‐fixed paraffin‐embedded tissues for analysis by matrix‐assisted laser desorption … AM Judd, DB Gutierrez, JL Moore, NH Patterson, J Yang, CE Romer, ... Journal of mass spectrometry 54 (8), 716-727, 2019 | 46 | 2019 |
Mapping the triglyceride distribution in NAFLD human liver by MALDI imaging mass spectrometry reveals molecular differences in micro and macro steatosis H Alamri, NH Patterson, E Yang, P Zoroquiain, A Lazaris, P Chaurand, ... Analytical and bioanalytical chemistry 411, 885-894, 2019 | 38 | 2019 |
Lipid landscape of the human retina and supporting tissues revealed by high-resolution imaging mass spectrometry DMG Anderson, JD Messinger, NH Patterson, ES Rivera, A Kotnala, ... Journal of the American Society for Mass Spectrometry 31 (12), 2426-2436, 2020 | 37 | 2020 |
Viv: multiscale visualization of high-resolution multiplexed bioimaging data on the web T Manz, I Gold, NH Patterson, C McCallum, MS Keller, BW Herr, K Börner, ... Nature methods 19 (5), 515-516, 2022 | 35 | 2022 |
Discovering new lipidomic features using cell type specific fluorophore expression to provide spatial and biological specificity in a multimodal workflow with MALDI imaging … MA Jones, SH Cho, NH Patterson, R Van de Plas, JM Spraggins, ... Analytical chemistry 92 (10), 7079-7086, 2020 | 34 | 2020 |
Single-cell mass spectrometry reveals changes in lipid and metabolite expression in RAW 264.7 cells upon lipopolysaccharide stimulation B Yang, NH Patterson, T Tsui, RM Caprioli, JL Norris Journal of The American Society for Mass Spectrometry 29 (5), 1012-1020, 2018 | 34 | 2018 |