Cohesin loss eliminates all loop domains SSP Rao, SC Huang, BG St Hilaire, JM Engreitz, EM Perez, ... Cell 171 (2), 305-320. e24, 2017 | 1764 | 2017 |
Local regulation of gene expression by lncRNA promoters, transcription and splicing JM Engreitz, JE Haines, EM Perez, G Munson, J Chen, M Kane, ... Nature 539 (7629), 452-455, 2016 | 1279 | 2016 |
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome JM Engreitz, A Pandya-Jones, P McDonel, A Shishkin, K Sirokman, ... Science 341 (6147), 1237973, 2013 | 1140 | 2013 |
The Lin28/let-7 axis regulates glucose metabolism H Zhu, N Shyh-Chang, AV Segrè, G Shinoda, SP Shah, WS Einhorn, ... Cell 147 (1), 81-94, 2011 | 1011 | 2011 |
Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA S Schwartz, DA Bernstein, MR Mumbach, M Jovanovic, RH Herbst, ... Cell 159 (1), 148-162, 2014 | 996 | 2014 |
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ... Nature genetics 51 (12), 1664-1669, 2019 | 813 | 2019 |
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre E Hacisuleyman, LA Goff, C Trapnell, A Williams, J Henao-Mejia, L Sun, ... Nature structural & molecular biology 21 (2), 198-206, 2014 | 706 | 2014 |
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ... Nature 595 (7865), 107-113, 2021 | 681 | 2021 |
Systematic mapping of functional enhancer–promoter connections with CRISPR interference CP Fulco, M Munschauer, R Anyoha, G Munson, SR Grossman, EM Perez, ... Science 354 (6313), 769-773, 2016 | 641 | 2016 |
Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression JM Engreitz, N Ollikainen, M Guttman Nature reviews Molecular cell biology 17 (12), 756-770, 2016 | 621 | 2016 |
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses KD Moynihan, CF Opel, GL Szeto, A Tzeng, EF Zhu, JM Engreitz, ... Nature medicine 22 (12), 1402-1410, 2016 | 566 | 2016 |
Inherited causes of clonal haematopoiesis in 97,691 whole genomes AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ... Nature 586 (7831), 763-768, 2020 | 540 | 2020 |
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites JM Engreitz, K Sirokman, P McDonel, AA Shishkin, C Surka, P Russell, ... Cell 159 (1), 188-199, 2014 | 526 | 2014 |
Genome-wide enhancer maps link risk variants to disease genes J Nasser, DT Bergman, CP Fulco, P Guckelberger, BR Doughty, ... Nature 593 (7858), 238-243, 2021 | 472 | 2021 |
A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ... Cell 170 (3), 522-533. e15, 2017 | 438 | 2017 |
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548 (7667), 343-346, 2017 | 423 | 2017 |
Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis RK Khajuria, M Munschauer, JC Ulirsch, C Fiorini, LS Ludwig, ... Cell 173 (1), 90-103. e19, 2018 | 375 | 2018 |
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability M Munschauer, CT Nguyen, K Sirokman, CR Hartigan, L Hogstrom, ... Nature 561 (7721), 132-136, 2018 | 362 | 2018 |
Recurrent and functional regulatory mutations in breast cancer E Rheinbay, P Parasuraman, J Grimsby, G Tiao, JM Engreitz, J Kim, ... Nature 547 (7661), 55-60, 2017 | 334 | 2017 |
Systematic dissection of genomic features determining transcription factor binding and enhancer function SR Grossman, X Zhang, L Wang, J Engreitz, A Melnikov, P Rogov, ... Proceedings of the National Academy of Sciences 114 (7), E1291-E1300, 2017 | 190 | 2017 |