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Joseph Adams
Joseph Adams
Professor of Pharmacology
Dirección de correo verificada de ucsd.edu - Página principal
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Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
A Miyawaki, J Llopis, R Heim, JM McCaffery, JA Adams, M Ikura, RY Tsien
Nature 388 (6645), 882-887, 1997
41471997
Kinetic and catalytic mechanisms of protein kinases
JA Adams
Chemical reviews 101 (8), 2271-2290, 2001
8092001
cAMP‐dependent protein kinase: Crystallographic insights into substrate recognition and phosphotransfer
Madhusudan, EA Trafny, NH Xuong, JA Adams, LFT Eyck, SS Taylor, ...
Protein Science 3 (2), 176-187, 1994
3361994
Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?
JA Adams
Biochemistry 42 (3), 601-607, 2003
3012003
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
Z Zhou, J Qiu, W Liu, Y Zhou, RM Plocinik, H Li, Q Hu, G Ghosh, ...
Molecular cell 47 (3), 422-433, 2012
2782012
A reassessment of cardiac toxicity associated with Taxol.
SG Arbuck, H Strauss, E Rowinsky, M Christian, M Suffness, J Adams, ...
Journal of the National Cancer Institute. Monographs, 117-130, 1993
2701993
Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2
JCK Ngo, S Chakrabarti, JH Ding, A Velazquez-Dones, B Nolen, ...
Molecular cell 20 (1), 77-89, 2005
2532005
Phosphorylation mechanism and structure of serine‐arginine protein kinases
G Ghosh, JA Adams
The FEBS journal 278 (4), 587-597, 2011
2412011
Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones
XY Zhong, JH Ding, JA Adams, G Ghosh, XD Fu
Genes & development 23 (4), 482-495, 2009
2222009
Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments
JA Adams, SS Taylor
Biochemistry 31 (36), 8516-8522, 1992
2161992
Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase
JA Adams, ML McGlone, R Gibson, SS Taylor
Biochemistry 34 (8), 2447-2454, 1995
1971995
Regulated cellular partitioning of SR protein-specific kinases in mammalian cells
JH Ding, XY Zhong, JC Hagopian, MM Cruz, G Ghosh, J Feramisco, ...
Molecular biology of the cell 17 (2), 876-885, 2006
1572006
Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques
BD Grant, JA Adams
Biochemistry 35 (6), 2022-2029, 1996
1561996
Matrix rigidity controls epithelial-mesenchymal plasticity and tumor metastasis via a mechanoresponsive EPHA2/LYN complex
L Fattet, HY Jung, MW Matsumoto, BE Aubol, A Kumar, JA Adams, ...
Developmental cell 54 (3), 302-316. e7, 2020
1542020
Paclitaxel activity in heavily pretreated breast cancer: a National Cancer Institute Treatment Referral Center trial.
JS Abrams, DA Vena, J Baltz, J Adams, M Montello, M Christian, N Onetto, ...
Journal of clinical oncology 13 (8), 2056-2065, 1995
1461995
Processive phosphorylation of alternative splicing factor/splicing factor 2
BE Aubol, S Chakrabarti, J Ngo, J Shaffer, B Nolen, XD Fu, G Ghosh, ...
Proceedings of the National Academy of Sciences 100 (22), 12601-12606, 2003
1442003
The role of the putative catalytic base in the phosphoryl transfer reaction in a protein kinase: first-principles calculations
M Valiev, R Kawai, JA Adams, JH Weare
Journal of the American Chemical Society 125 (33), 9926-9927, 2003
1372003
Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations
M Valiev, J Yang, JA Adams, SS Taylor, JH Weare
The Journal of Physical Chemistry B 111 (47), 13455-13464, 2007
1362007
Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations
M Valiev, J Yang, JA Adams, SS Taylor, JH Weare
The Journal of Physical Chemistry B 111 (47), 13455-13464, 2007
1362007
A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1
JCK Ngo, K Giang, S Chakrabarti, CT Ma, N Huynh, JC Hagopian, ...
Molecular cell 29 (5), 563-576, 2008
1282008
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Artículos 1–20