Ester Lázaro
Ester Lázaro
Investigadora del Centro de Astrobiología (CSIC-INTA)
Dirección de correo verificada de
Citado por
Citado por
Suppression of viral infectivity through lethal defection
A Grande-Pérez, E Lázaro, P Lowenstein, E Domingo, SC Manrubia
Proceedings of the National Academy of Sciences 102 (12), 4448-4452, 2005
Quasispecies dynamics and RNA virus extinction
E Domingo, C Escarmís, E Lázaro, SC Manrubia
Virus research 107 (2), 129-139, 2005
Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss
E Lázaro, C Escarmís, J Pérez-Mercader, SC Manrubia, E Domingo
Proceedings of The National Academy of Sciences 100 (19), 10830-10835, 2003
High mutation rates, bottlenecks, and robustness of RNA viral quasispecies
SC Manrubia, C Escarmís, E Domingo, E Lázaro
Gene 347 (2), 273-282, 2005
Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning
A Arias, E Lázaro, C Escarmís, E Domingo
Journal of General Virology 82 (5), 1049-1060, 2001
Analysis of ribavirin mutagenicity in human hepatitis C virus infection
S Chevaliez, R Brillet, E Lázaro, C Hézode, JM Pawlotsky
Journal of virology 81 (14), 7732-7741, 2007
Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: diversification by mutation clustering
C Escarmı́s, G Gómez-Mariano, M Dávila, E Lázaro, E Domingo
Journal of molecular biology 315 (4), 647-661, 2002
Population bottlenecks in quasispecies dynamics
C Escarmís, E Lázaro, SC Manrubia
Quasispecies: concept and implications for virology, 141-170, 2006
Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitness
E Lázaro, C Escarmís, E Domingo, SC Manrubia
Journal of virology 76 (17), 8675-8681, 2002
Pathways to extinction: beyond the error threshold
SC Manrubia, E Domingo, E Lázaro
Philosophical Transactions of the Royal Society B: Biological Sciences 365 …, 2010
Foot-and-mouth disease virus evolution: exploring pathways towards virus extinction
E Domingo, N Pariente, A Airaksinen, C González-López, S Sierra, ...
Foot-and-mouth disease virus, 149-173, 2005
Viral evolution
SC Manrubia, E Lázaro
Physics of Life Reviews 3 (2), 65-92, 2006
Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction
C Escarmís, E Lázaro, A Arias, E Domingo
Journal of molecular biology 376 (2), 367-379, 2008
A Sparsomycin-resistant Mutant ofHalobacterium salinariumLacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNA
E Lázaro, C Rodriguez-Fonseca, B Porse, D Ureña, RA Garrett, ...
Journal of molecular biology 261 (2), 231-238, 1996
Beneficial effects of population bottlenecks in an RNA virus evolving at increased error rate
C Cases-González, M Arribas, E Domingo, E Lázaro
Journal of molecular biology 384 (5), 1120-1129, 2008
Fitness distributions in exponentially growing asexual populations
SC Manrubia, E Lázaro, J Pérez-Mercader, C Escarmís, E Domingo
Physical review letters 90 (18), 188102, 2003
Biochemical and kinetic characteristics of the interaction of the antitumor antibiotic sparsomycin with prokaryotic and eukaryotic ribosomes
E Lazaro, LAGM Van den Broek, A San Felix, HCJ Ottenheijm, ...
Biochemistry 30 (40), 9642-9648, 1991
Variable mutation rates as an adaptive strategy in replicator populations
M Stich, SC Manrubia, E Lázaro
PLoS One 5 (6), e11186, 2010
Lipophilic analogs of sparsomycin as strong inhibitors of protein synthesis and tumor growth: a structure-activity relationship study
LAGM Van den Broek, E Lazaro, Z Zylicz, PJ Fennis, FAN Missler, ...
Journal of medicinal chemistry 32 (8), 2002-2015, 1989
Evolution at increased error rate leads to the coexistence of multiple adaptive pathways in an RNA virus
L Cabanillas, M Arribas, E Lázaro
BMC evolutionary biology 13 (1), 1-16, 2013
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