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Astrid Sasse
Astrid Sasse
Associate Professor in Pharmaceutical Chemistry, Trinity College Dublin
Dirección de correo verificada de tcd.ie
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Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti …
J Meng, SV Ovsepian, J Wang, M Pickering, A Sasse, KR Aoki, ...
Journal of Neuroscience 29 (15), 4981-4992, 2009
2592009
Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
N Eissa, M Al-Houqani, A Sadeq, SK Ojha, A Sasse, B Sadek
Frontiers in neuroscience 12, 325601, 2018
2372018
Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics
J Wang, J Meng, GW Lawrence, TH Zurawski, A Sasse, MDO Bodeker, ...
Journal of Biological Chemistry 283 (25), 16993-17002, 2008
1312008
The rat H 3 receptor: gene organization and multiple isoforms
S Morisset, A Sasse, F Gbahou, A Héron, X Ligneau, J Tardivel-Lacombe, ...
Biochemical and biophysical research communications 280 (1), 75-80, 2001
912001
Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model
H Tezval, O Jahn, C Todorovic, A Sasse, K Eckart, J Spiess
Proceedings of the National Academy of Sciences 101 (25), 9468-9473, 2004
872004
Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?
N Eissa, A Sadeq, A Sasse, B Sadek
Frontiers in pharmacology 11, 521283, 2020
712020
Self-assembled carrageenan/protamine polyelectrolyte nanoplexes—Investigation of critical parameters governing their formation and characteristics
M Dul, KJ Paluch, H Kelly, AM Healy, A Sasse, L Tajber
Carbohydrate Polymers 123, 339-349, 2015
622015
New histamine H3-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency
A Sasse, B Sadek, X Ligneau, S Elz, HH Pertz, P Luger, CR Ganellin, ...
Journal of medicinal chemistry 43 (17), 3335-3343, 2000
512000
Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons
C Weiss, E Sametsky, A Sasse, J Spiess, JF Disterhoft
Learning & Memory 12 (2), 138-143, 2005
502005
Novel partial agonists for the histamine H3 receptor with high in vitro and in vivo activity
A Sasse, H Stark, S Reidemeister, A Hüls, S Elz, X Ligneau, CR Ganellin, ...
Journal of medicinal chemistry 42 (20), 4269-4274, 1999
381999
Galloylquinic acid derivatives from Copaifera langsdorffii leaves display gastroprotective activity
EVS Motta, M Lemos, JC Costa, VC Banderó-Filho, A Sasse, H Sheridan, ...
Chemico-Biological Interactions 261, 145-155, 2017
362017
Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity
A Sasse, K Kiec-Kononowicz, H Stark, M Motyl, S Reidemeister, ...
Journal of medicinal chemistry 42 (4), 593-600, 1999
351999
Benzophenone Derivatives and Related Compounds as Potent Histamine H3‐Receptor Antagonists and Potential PET/SPECT Ligands
A Sasse, X Ligneau, B Sadek, S Elz, HH Pertz, CR Ganellin, JM Arrang, ...
Archiv der Pharmazie 334 (2), 45-52, 2001
302001
(Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H 3 receptors
A Sasse, H Stark, X Ligneau, S Elz, S Reidemeister, CR Ganellin, ...
Bioorganic & medicinal chemistry 8 (5), 1139-1149, 2000
292000
influence of bulky substituents on histamine H3 receptor agonist/antagonist properties
A Sasse, X Ligneau, A Rouleau, S Elz, CR Ganellin, JM Arrang, ...
Journal of medicinal chemistry 45 (18), 4000-4010, 2002
282002
Polymorphisms and genetic linkage of histamine receptors
S Micallef, H Stark, A Sasse
Life sciences 93 (15), 487-494, 2013
262013
Novel histamine H3‐receptor antagonists and partial agonists with a non‐aminergic structure
T Nickel, U Bauer, E Schlicker, M Kathmann, M Göthert, A Sasse, H Stark, ...
British journal of pharmacology 132 (8), 1665-1672, 2001
202001
Design and implementation of an integrated competency-focused pharmacy programme: a case report
TJ Ryan, T Grimes, MC Henman, EN Sheachnasaigh, M O’Dwyer, ...
Pharmacy 7 (3), 121, 2019
192019
Traditional Chinese Medicine: From Aqueous Extracts to Therapeutic Formulae
J Wang, A Sasse, H Sheridan
Plant Extracts, 2019
192019
Application of genomics to drug design: the example of the histamine H 3 receptor
JC Schwartz, S Morisset, A Rouleau, J Tardivel-Lacombe, F Gbahou, ...
European Neuropsychopharmacology 11 (6), 441-448, 2001
192001
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Artículos 1–20