| Novel three-component domino reactions of ketones, isatin and amino acids: Synthesis and discovery of antimycobacterial activity of highly functionalised novel dispiropyrrolidines RS Kumar, SM Rajesh, S Perumal, D Banerjee, P Yogeeswari, D Sriram European journal of medicinal chemistry 45 (1), 411-422, 2010 | 165 | 2010 |
| Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio-and stereoselective 1, 3-dipolar cycloaddition SM Rajesh, S Perumal, JC Menéndez, P Yogeeswari, D Sriram MedChemComm 2 (7), 626-630, 2011 | 148 | 2011 |
| L-Proline-catalysed sequential four-component “on water” protocol for the synthesis of structurally complex heterocyclic ortho-quinones SM Rajesh, BD Bala, S Perumal, JC Menéndez Green chemistry 13 (11), 3248-3254, 2011 | 106 | 2011 |
| Novel benzodiazepine-like ligands with various anxiolytic, antidepressant, or pro-cognitive profiles TD Prevot, G Li, A Vidojevic, KA Misquitta, C Fee, A Santrac, DE Knutson, ... Molecular neuropsychiatry 5 (2), 84-97, 2019 | 75 | 2019 |
| eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures H Christopher, T Elham, M Luca, P Luisa, C Angela, FC Guarnieri, ... Cerebral Cortex 26 (5), 1-23, 2016 | 73* | 2016 |
| A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity SM Rajesh, RS Kumar, LA Libertsen, S Perumal, P Yogeeswari, D Sriram Bioorganic & medicinal chemistry letters 21 (10), 3012-3016, 2011 | 67 | 2011 |
| Facile ionic liquid-mediated, three-component sequential reactions for the green, regio-and diastereoselective synthesis of furocoumarins SM Rajesh, S Perumal, JC Menéndez, S Pandian, R Murugesan Tetrahedron 68 (27-28), 5631-5636, 2012 | 62 | 2012 |
| Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and … DE Knutson, R Kodali, B Divović, M Treven, MR Stephen, NM Zahn, ... Journal of medicinal chemistry 61 (6), 2422−2446, 2018 | 59 | 2018 |
| Multi-component, 1, 3-dipolar cycloaddition reactions for the chemo-, regio-and stereoselective synthesis of novel hybrid spiroheterocycles in ionic liquid SM Rajesh, BD Bala, S Perumal Tetrahedron Letters 53 (40), 5367-5371, 2012 | 51 | 2012 |
| 1, 3-Dipolar cycloaddition of nitrile oxides to (R)-1-(1-phenylethyl)-3, 5-bis [(E)-arylmethylidene] tetrahydro-4 (1H)-pyridinones: synthesis and antimycobacterial evaluation … RS Kumar, SM Rajesh, S Perumal, P Yogeeswari, D Sriram Tetrahedron: Asymmetry 21 (11-12), 1315-1327, 2010 | 49 | 2010 |
| A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung GS Forkuo, AN Nieman, R Kodali, NM Zahn, G Li, MS Rashid Roni, ... Molecular pharmaceutics 15 (5), 1766-1777, 2018 | 47 | 2018 |
| An eco-friendly sequential catalyst-and solvent-free four-component stereoselective synthesis of novel 1, 4-pyranonaphthoquinones BD Bala, SM Rajesh, S Perumal Green chemistry 14 (9), 2484-2490, 2012 | 44 | 2012 |
| A microwave-mediated catalyst-and solvent-free regioselective Biginelli reaction in the synthesis of highly functionalized novel tetrahydropyrimidines PS Harikrishnan, SM Rajesh, S Perumal, AI Almansour Tetrahedron Letters 54 (9), 1076-1079, 2012 | 39 | 2012 |
| Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma treatments GS Forkuo, ML Guthrie, NY Yuan, AN Nieman, R Kodali, R Jahan, ... Molecular Pharmaceutics 13 (6), 2026–2038, 2016 | 38 | 2016 |
| Targeting the GABAA Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction GT Yocum, G Gallos, Y Zhang, R Jahan, MR Stephen, Z Varagic, ... American Journal of Respiratory Cell and Molecular Biology 54 (4), 546-553, 2016 | 36 | 2016 |
| Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death L Kallay, H Keskin, A Ross, M Rupji, OA Moody, X Wang, G Li, T Ahmed, ... Journal of neuro-oncology 142, 411-422, 2019 | 32 | 2019 |
| Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators GS Forkuo, AN Nieman, NY Yuan, R Kodali, OB Yu, NM Zahn, R Jahan, ... Molecular pharmaceutics 14 (6), 2088-2098, 2017 | 32 | 2017 |
| Optimization of substituted imidazobenzodiazepines as novel asthma treatments R Jahan, MR Stephen, GS Forkuo, R Kodali, ML Guthrie, AN Nieman, ... European Journal of Medicinal Chemistry 126, 550-560, 2017 | 30 | 2017 |
| Concise Total Synthesis of (−)‐Affinisine Oxindole, (+)‐Isoalstonisine, (+)‐Alstofoline, (−)‐Macrogentine, (+)‐Na‐Demethylalstonisine, (−)‐Alstonoxine A, and (+ … MR Stephen, MT Rahman, VVNPB Tiruveedhula, GO Fonseca, ... Chemistry–A European Journal 23 (62), 15805-15819, 2017 | 27 | 2017 |
| Evidence that sedative effects of benzodiazepines involve unexpected GABAA receptor subtypes: quantitative observation studies in rhesus monkeys AN Duke, Z Meng, DM Platt, JR Atack, GR Dawson, DS Reynolds, ... Journal of Pharmacology and Experimental Therapeutics 366 (1), 145-157, 2018 | 24 | 2018 |
james cookProfessor of Chemistry, University of Wisconsin MilwaukeeVerified email at uwm.edu
