Rob Hegele
Rob Hegele
Western University, Robarts Research Institute
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Biological, clinical and population relevance of 95 loci for blood lipids
TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ...
Nature 466 (7307), 707-713, 2010
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of …
BG Nordestgaard, MJ Chapman, SE Humphries, HN Ginsberg, L Masana, ...
European heart journal 34 (45), 3478-3490, 2013
Differences in risk factors, atherosclerosis, and cardiovascular disease between ethnic groups in Canada: the Study of Health Assessment and Risk in Ethnic groups (SHARE)
SS Anand, S Yusuf, V Vuksan, S Devanesen, KK Teo, PA Montague, ...
The lancet 356 (9226), 279-284, 2000
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European …
BA Ference, HN Ginsberg, I Graham, KK Ray, CJ Packard, E Bruckert, ...
European heart journal 38 (32), 2459-2472, 2017
2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult–2009 recommendations
J Genest, R McPherson, J Frohlich, T Anderson, N Campbell, ...
Canadian Journal of Cardiology 25 (10), 567-579, 2009
Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society consensus panel statement on assessment, aetiology and management
ES Stroes, PD Thompson, A Corsini, GD Vladutiu, FJ Raal, KK Ray, ...
European heart journal 36 (17), 1012-1022, 2015
2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult
TJ Anderson, J Grégoire, RA Hegele, P Couture, GBJ Mancini, ...
Canadian Journal of Cardiology 29 (2), 151-167, 2013
Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy
H Cao, RA Hegele
Human molecular genetics 9 (1), 109-112, 2000
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on …
M Cuchel, E Bruckert, HN Ginsberg, FJ Raal, RD Santos, RA Hegele, ...
European heart journal 35 (32), 2146-2157, 2014
Hypertriglyceridemia: its etiology, effects and treatment
G Yuan, KZ Al-Shali, RA Hegele
Cmaj 176 (8), 1113-1120, 2007
Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins.
MI Mackness, B Mackness, PN Durrington, PW Connelly, RA Hegele
Current opinion in lipidology 7 (2), 69-76, 1996
2016 Canadian Cardiovascular Society guidelines for the management of dyslipidemia for the prevention of cardiovascular disease in the adult
TJ Anderson, J Grégoire, GJ Pearson, AR Barry, P Couture, M Dawes, ...
Canadian Journal of Cardiology 32 (11), 1263-1282, 2016
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
M Cuchel, EA Meagher, H du Toit Theron, DJ Blom, AD Marais, ...
The Lancet 381 (9860), 40-46, 2013
Diagnosing heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics
RR Williams, SC Hunt, MC Schumacher, RA Hegele, MF Leppert, ...
The American journal of cardiology 72 (2), 171-176, 1993
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
R Do, NO Stitziel, HH Won, AB Jørgensen, S Duga, PA Merlini, A Kiezun, ...
Nature 518 (7537), 102-106, 2015
Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia
C Gagné, D Gaudet, E Bruckert
Circulation 105 (21), 2469-2475, 2002
Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
A Wiegman, SS Gidding, GF Watts, MJ Chapman, HN Ginsberg, M Cuchel, ...
European heart journal 36 (36), 2425-2437, 2015
Narrative review: statin-related myopathy
TR Joy, RA Hegele
Annals of internal medicine 150 (12), 858-868, 2009
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia
CT Johansen, J Wang, MB Lanktree, H Cao, AD McIntyre, MR Ban, ...
Nature genetics 42 (8), 684-687, 2010
Plasma lipoproteins: genetic influences and clinical implications
RA Hegele
Nature Reviews Genetics 10 (2), 109-121, 2009
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Artículos 1–20