p23 and HSP20/α-crystallin proteins define a conserved sequence domain present in other eukaryotic protein families JA Garcia-Ranea, G Mirey, J Camonis, A Valencia FEBS letters 529 (2-3), 162-167, 2002 | 183 | 2002 |
Assessing protein co-evolution in the context of the tree of life assists in the prediction of the interactome F Pazos, JAG Ranea, D Juan, MJE Sternberg Journal of molecular biology 352 (4), 1002-1015, 2005 | 163 | 2005 |
Protein superfamily evolution and the last universal common ancestor (LUCA) JAG Ranea, A Sillero, JM Thornton, CA Orengo Journal of Molecular Evolution 63, 513-525, 2006 | 135 | 2006 |
Evolution of protein superfamilies and bacterial genome size JAG Ranea, DWA Buchan, JM Thornton, CA Orengo Journal of molecular biology 336 (4), 871-887, 2004 | 118 | 2004 |
Regulatory variants: from detection to predicting impact E Rojano, P Seoane, JAG Ranea, JR Perkins Briefings in bioinformatics 20 (5), 1639-1654, 2019 | 117 | 2019 |
The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors P Vargiu, RD Abajo, JA Garcia-Ranea, A Valencia, P Santisteban, ... Oncogene 23 (2), 559-568, 2004 | 108 | 2004 |
Distribution and functional diversification of the ras superfamily in Saccharomyces cerevisiae JA Garcia-Ranea, A Valencia FEBS letters 434 (3), 219-225, 1998 | 103 | 1998 |
Effector recognition by the small GTP-binding proteins Ras and Ral B Bauer, G Mirey, IR Vetter, JA Garcıa-Ranea, A Valencia, A Wittinghofer, ... Journal of Biological Chemistry 274 (25), 17763-17770, 1999 | 101 | 1999 |
Microeconomic principles explain an optimal genome size in bacteria JAG Ranea, A Grant, JM Thornton, CA Orengo Trends in Genetics 21 (1), 21-25, 2005 | 76 | 2005 |
Model of the ran-RCC1 interaction using biochemical and docking experiments Y Azuma, L Renault, JA Garcı́a-Ranea, A Valencia, T Nishimoto, ... Journal of molecular biology 289 (4), 1119-1130, 1999 | 73 | 1999 |
Predicting protein function with hierarchical phylogenetic profiles: the Gene3D Phylo-Tuner method applied to eukaryotic genomes JAG Ranea, C Yeats, A Grant, CA Orengo PLoS computational biology 3 (11), e237, 2007 | 64 | 2007 |
RhoGAPs and RhoGDIs,(His) stories of two families G Zalcman, O Dorseuil, JA Garcia-Ranea, G Gacon, J Camonis Cytoskeleton and Small G Proteins, 85-113, 1999 | 62 | 1999 |
Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation JK Hériché, JG Lees, I Morilla, T Walter, B Petrova, MJ Roberti, ... Molecular biology of the cell 25 (16), 2522-2536, 2014 | 53 | 2014 |
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus J Caro-Astorga, E Frenzel, JR Perkins, A Álvarez-Mena, A De Vicente, ... NPJ biofilms and microbiomes 6 (1), 3, 2020 | 52 | 2020 |
Systematic computational prediction of protein interaction networks JG Lees, JK Heriche, I Morilla, JA Ranea, CA Orengo Physical biology 8 (3), 035008, 2011 | 49 | 2011 |
Structural and functional view of polypharmacology A Moya-García, T Adeyelu, FA Kruger, NL Dawson, JG Lees, ... Scientific reports 7 (1), 10102, 2017 | 47 | 2017 |
Heparan sulphate mediates swine vesicular disease virus attachment to the host cell E Escribano-Romero, MA Jimenez-Clavero, P Gomes, JA García-Ranea, ... Journal of general virology 85 (3), 653-663, 2004 | 41 | 2004 |
The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold KSR1 occurs in an isoform-specific manner LR Jagemann, LG Perez-Rivas, EJ Ruiz, JA Ranea, F Sanchez-Jimenez, ... Journal of Biological Chemistry 283 (25), 17450-17462, 2008 | 40 | 2008 |
Evolutionary expansion of the Ras switch regulatory module in eukaryotes D Díez, F Sanchez-Jimenez, JAG Ranea Nucleic acids research 39 (13), 5526-5537, 2011 | 36 | 2011 |
Characterization of neutralization sites on the circulating variant of swine vesicular disease virus (SVDV): a new site is shared by SVDV and the related coxsackie B5 virus B Borrego, E Carra, JA García-Ranea, E Brocchi Journal of general virology 83 (1), 35-44, 2002 | 36 | 2002 |