Bon-Kyoung Koo
Bon-Kyoung Koo
Institute of Molecular Biotechnology (IMBA) - The Austrian Academy of Sciences
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Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ...
Cell stem cell 13 (6), 653-658, 2013
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ...
Nature 476 (7360), 293-297, 2011
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ...
Nature 488 (7413), 665-669, 2012
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers
J Muñoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ...
The EMBO journal 31 (14), 3079-3091, 2012
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarró, ...
Nature medicine 23 (12), 1424, 2017
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ...
Cell 155 (2), 357-368, 2013
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
L Broutier, A Andersson-Rolf, CJ Hindley, SF Boj, H Clevers, BK Koo, ...
Nature protocols 11 (9), 1724, 2016
Modeling mouse and human development using organoid cultures
M Huch, BK Koo
Development 142 (18), 3113-3125, 2015
Controlled gene expression in primary Lgr5 organoid cultures
BK Koo, DE Stange, T Sato, W Karthaus, HF Farin, M Huch, JH Van Es, ...
Nature methods 9 (1), 81-83, 2012
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch
BK Koo, HS Lim, R Song, MJ Yoon, KJ Yoon, JS Moon, YW Kim, M Kwon, ...
Development 132 (15), 3459-3470, 2005
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ...
Molecular and cellular biology 32 (10), 1918-1927, 2012
A crucial role of WW45 in developing epithelial tissues in the mouse
JH Lee, TS Kim, TH Yang, BK Koo, SP Oh, KP Lee, HJ Oh, SH Lee, ...
The EMBO journal 27 (8), 1231-1242, 2008
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts
J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ...
Cell stem cell 16 (2), 158-170, 2015
Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium
MY Turco, L Gardner, J Hughes, T Cindrova-Davies, MJ Gomez, L Farrell, ...
Nature cell biology 19 (5), 568-577, 2017
Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells
KJ Yoon, BK Koo, SK Im, HW Jeong, J Ghim, M Kwon, JS Moon, T Miyata, ...
Neuron 58 (4), 519-531, 2008
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response
J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ...
Cell reports 3 (4), 1128-1139, 2013
Receptor activator of NF-κB ligand regulates the proliferation of mammary epithelial cells via Id2
NS Kim, HJ Kim, BK Koo, MC Kwon, YW Kim, Y Cho, Y Yokota, ...
Molecular and cellular biology 26 (3), 1002-1013, 2006
Defective Notch activation in microenvironment leads to myeloproliferative disease
YW Kim, BK Koo, HW Jeong, MJ Yoon, R Song, J Shin, DC Jeong, ...
Blood 112 (12), 4628-4638, 2008
Stem cells marked by the R-spondin receptor LGR5
BK Koo, H Clevers
Gastroenterology 147 (2), 289-302, 2014
Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer
HA Kim, BK Koo, JH Cho, YY Kim, J Seong, HJ Chang, YM Oh, ...
The Journal of clinical investigation 122 (9), 3248-3259, 2012
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20