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Raymond K Tong
Raymond K Tong
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Verified email at dnli.com - Homepage
Title
Cited by
Cited by
Year
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
Q Pan, Y Chanthery, WC Liang, S Stawicki, J Mak, N Rathore, RK Tong, ...
Cancer cell 11 (1), 53-67, 2007
6712007
Blocking neuropilin-2 function inhibits tumor cell metastasis
M Caunt, J Mak, WC Liang, S Stawicki, Q Pan, RK Tong, J Kowalski, C Ho, ...
Cancer cell 13 (4), 331-342, 2008
4172008
Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates
YJ Yu, JK Atwal, Y Zhang, RK Tong, KR Wildsmith, C Tan, N Bien-Ly, ...
Science translational medicine 6 (261), 261ra154-261ra154, 2014
3652014
Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting
Q Pan, Y Chathery, Y Wu, N Rathore, RK Tong, F Peale, A Bagri, ...
Journal of Biological Chemistry 282 (33), 24049-24056, 2007
2662007
Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier
JA Couch, YJ Yu, Y Zhang, JM Tarrant, RN Fuji, WJ Meilandt, H Solanoy, ...
Science translational medicine 5 (183), 183ra57-183ra57, 2013
2592013
Effector-attenuating substitutions that maintain antibody stability and reduce toxicity in mice
M Lo, HS Kim, RK Tong, TW Bainbridge, JM Vernes, Y Zhang, YL Lin, ...
Journal of Biological Chemistry 292 (9), 3900-3908, 2017
2572017
Discovery of novel blood-brain barrier targets to enhance brain uptake of therapeutic antibodies
YJY Zuchero, X Chen, N Bien-Ly, D Bumbaca, RK Tong, X Gao, S Zhang, ...
Neuron 89 (1), 70-82, 2016
2522016
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo
FL Bos, M Caunt, J Peterson-Maduro, L Planas-Paz, J Kowalski, ...
Circulation research 109 (5), 486-491, 2011
2432011
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B
AW Koch, T Mathivet, B Larrivée, RK Tong, J Kowalski, L Pibouin-Fragner, ...
Developmental cell 20 (1), 33-46, 2011
2202011
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ...
Science translational medicine 12 (545), eaay1359, 2020
2192020
Sustained brown fat stimulation and insulin sensitization by a humanized bispecific antibody agonist for fibroblast growth factor receptor 1/βKlotho complex
G Kolumam, MZ Chen, R Tong, J Zavala-Solorio, L Kates, N van Bruggen, ...
EBioMedicine 2 (7), 730-743, 2015
1092015
Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2
A Jaworski, I Tom, RK Tong, HK Gildea, AW Koch, LC Gonzalez, ...
Science 350 (6263), 961-965, 2015
1022015
Molecular understanding of USP7 substrate recognition and C-terminal activation
L Rougé, TW Bainbridge, M Kwok, R Tong, P Di Lello, IE Wertz, T Maurer, ...
Structure 24 (8), 1335-1345, 2016
932016
The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
F Zhang, C Prahst, T Mathivet, L Pibouin-Fragner, J Zhang, G Genet, ...
Nature communications 7 (1), 13517, 2016
512016
MR angiogenesis imaging with Robo4-vs. αVβ3-targeted nanoparticles in a B16/F10 mouse melanoma model
KS Boles, AH Schmieder, AW Koch, RAD Carano, Y Wu, SD Caruthers, ...
The FASEB Journal 24 (11), 4262, 2010
462010
Antiparallel conformation of knob and hole aglycosylated half-antibody homodimers is mediated by a CH2–CH3 hydrophobic interaction
JM Elliott, M Ultsch, J Lee, R Tong, K Takeda, C Spiess, C Eigenbrot, ...
Journal of molecular biology 426 (9), 1947-1957, 2014
452014
Pharmacokinetic and pharmacodynamic analysis of circulating biomarkers of anti-NRP1, a novel antiangiogenesis agent, in two phase I trials in patients with advanced solid tumors
Y Xin, J Li, J Wu, R Kinard, CD Weekes, A Patnaik, P LoRusso, ...
Clinical Cancer Research 18 (21), 6040-6048, 2012
442012
Prospective design of anti‐transferrin receptor bispecific antibodies for optimal delivery into the human brain
JS Kanodia, K Gadkar, D Bumbaca, Y Zhang, RK Tong, W Luk, K Hoyte, ...
CPT: pharmacometrics & systems pharmacology 5 (5), 283-291, 2016
392016
CD98hc is a target for brain delivery of biotherapeutics
KS Chew, RC Wells, A Moshkforoush, D Chan, KJ Lechtenberg, HL Tran, ...
nature communications 14 (1), 5053, 2023
102023
Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening
HS Kim, DR Dunshee, A Yee, RK Tong, I Kim, F Farahi, JA Hongo, ...
Protein Engineering, Design and Selection 30 (9), 627-637, 2017
102017
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