Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis F Mei, SPJ Fancy, YAA Shen, J Niu, C Zhao, B Presley, E Miao, S Lee, ... Nature medicine 20 (8), 954-960, 2014 | 554 | 2014 |
Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial AJ Green, JM Gelfand, BA Cree, C Bevan, WJ Boscardin, F Mei, J Inman, ... The Lancet 390 (10111), 2481-2489, 2017 | 465 | 2017 |
The neurotrophin receptor p75NTR as a positive modulator of myelination JM Cosgaya, JR Chan, EM Shooter Science 298 (5596), 1245-1248, 2002 | 464 | 2002 |
A culture system to study oligodendrocyte myelination processes using engineered nanofibers S Lee, MK Leach, SA Redmond, SYC Chong, SH Mellon, SJ Tuck, ... Nature methods 9 (9), 917-922, 2012 | 427 | 2012 |
Oligodendrocyte precursors migrate along vasculature in the developing nervous system HH Tsai, J Niu, R Munji, D Davalos, J Chang, H Zhang, AC Tien, CJ Kuo, ... Science 351 (6271), 379-384, 2016 | 399 | 2016 |
Regulatory T cells promote myelin regeneration in the central nervous system Y Dombrowski, T O'hagan, M Dittmer, R Penalva, SR Mayoral, ... Nature neuroscience 20 (5), 674-680, 2017 | 392 | 2017 |
Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation Y Yu, Y Chen, B Kim, H Wang, C Zhao, X He, L Liu, W Liu, LMN Wu, ... Cell 152 (1), 248-261, 2013 | 389 | 2013 |
NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes JR Chan, TA Watkins, JM Cosgaya, CZ Zhang, L Chen, LF Reichardt, ... Neuron 43 (2), 183-191, 2004 | 375 | 2004 |
Myelin regeneration: a recapitulation of development? SPJ Fancy, JR Chan, SE Baranzini, RJM Franklin, DH Rowitch Annual review of neuroscience 34, 21-43, 2011 | 360 | 2011 |
Neurotrophins are key mediators of the myelination program in the peripheral nervous system JR Chan, JM Cosgaya, YJ Wu, EM Shooter Proceedings of the National Academy of Sciences 98 (25), 14661-14668, 2001 | 338 | 2001 |
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity AV Molofsky, KW Kelley, HH Tsai, SA Redmond, SM Chang, L Madireddy, ... Nature 509 (7499), 189-194, 2014 | 301 | 2014 |
Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination SYC Chong, SS Rosenberg, SPJ Fancy, C Zhao, YAA Shen, AT Hahn, ... Proceedings of the National Academy of Sciences 109 (4), 1299-1304, 2012 | 260 | 2012 |
Preservation of a remote fear memory requires new myelin formation S Pan, SR Mayoral, HS Choi, JR Chan, MA Kheirbek Nature neuroscience 23 (4), 487-499, 2020 | 253 | 2020 |
Multiple sclerosis: prospects and promise SL Hauser, JR Chan, JR Oksenberg Annals of neurology 74 (3), 317-327, 2013 | 251 | 2013 |
Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery F Mei, K Lehmann-Horn, YAA Shen, KA Rankin, KJ Stebbins, DS Lorrain, ... Elife 5, e18246, 2016 | 248 | 2016 |
The geometric and spatial constraints of the microenvironment induce oligodendrocyte differentiation SS Rosenberg, EE Kelland, E Tokar, AR De La Torre, JR Chan Proceedings of the National Academy of Sciences 105 (38), 14662-14667, 2008 | 246 | 2008 |
Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture EM Ullian, BT Harris, A Wu, JR Chan, BA Barres Molecular and Cellular Neuroscience 25 (2), 241-251, 2004 | 233 | 2004 |
Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory F Wang, SY Ren, JF Chen, K Liu, RX Li, ZF Li, B Hu, JQ Niu, L Xiao, ... Nature neuroscience 23 (4), 481-486, 2020 | 229 | 2020 |
NGF regulates the expression of axonal LINGO-1 to inhibit oligodendrocyte differentiation and myelination X Lee, Z Yang, Z Shao, SS Rosenberg, M Levesque, RB Pepinsky, M Qiu, ... Journal of Neuroscience 27 (1), 220-225, 2007 | 218 | 2007 |
Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases J Yamauchi, JR Chan, EM Shooter Proceedings of the National Academy of Sciences 101 (23), 8774-8779, 2004 | 214 | 2004 |