| Synthesis of N1-arylidene-N2-quinolyl-and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains S Gemma, G Kukreja, C Fattorusso, M Persico, MP Romano, M Altarelli, ... Bioorganic & medicinal chemistry letters 16 (20), 5384-5388, 2006 | 248 | 2006 |
| Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77 C Ferlini, L Cicchillitti, G Raspaglio, S Bartollino, S Cimitan, C Bertucci, ... Cancer research 69 (17), 6906-6914, 2009 | 182 | 2009 |
| Design, synthesis, and structure–activity relationship studies of 4-quinolinyl-and 9-acrydinylhydrazones as potent antimalarial agents C Fattorusso, G Campiani, G Kukreja, M Persico, S Butini, MP Romano, ... Journal of medicinal chemistry 51 (5), 1333-1343, 2008 | 98 | 2008 |
| Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663 G Maga, S Gemma, C Fattorusso, GA Locatelli, S Butini, M Persico, ... Biochemistry 44 (28), 9637-9644, 2005 | 98 | 2005 |
| Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of … G Campiani, C Fattorusso, S Butini, A Gaeta, M Agnusdei, S Gemma, ... Journal of medicinal chemistry 48 (6), 1919-1929, 2005 | 90 | 2005 |
| Endoperoxide derivatives from marine organisms: 1, 2-dioxanes of the plakortin family as novel antimalarial agents C Fattorusso, G Campiani, B Catalanotti, M Persico, N Basilico, S Parapini, ... Journal of medicinal chemistry 49 (24), 7088-7094, 2006 | 80 | 2006 |
| Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors S Butini, G Campiani, M Borriello, S Gemma, A Panico, M Persico, ... Journal of medicinal chemistry 51 (11), 3154-3170, 2008 | 69 | 2008 |
| Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation CB Botta, W Cabri, E Cini, L De Cesare, C Fattorusso, G Giannini, ... Journal of Medicinal Chemistry 54 (7), 2165-2182, 2011 | 67 | 2011 |
| Combining 4-aminoquinoline-and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials S Gemma, G Campiani, S Butini, BP Joshi, G Kukreja, SS Coccone, ... Journal of medicinal chemistry 52 (2), 502-513, 2009 | 67 | 2009 |
| Manadoperoxides A−D from the Indonesian Sponge Plakortis cfr. simplex. Further Insights on the Structure−Activity Relationships of Simple 1,2-Dioxane … C Fattorusso, M Persico, B Calcinai, C Cerrano, S Parapini, D Taramelli, ... Journal of natural products 73 (6), 1138-1145, 2010 | 65 | 2010 |
| Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad … C Fattorusso, S Gemma, S Butini, P Huleatt, B Catalanotti, M Persico, ... Journal of medicinal chemistry 48 (23), 7153-7165, 2005 | 59 | 2005 |
| Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure–activity relationship studies S Gemma, G Campiani, S Butini, G Kukreja, SS Coccone, BP Joshi, ... Journal of medicinal chemistry 51 (5), 1278-1294, 2008 | 58 | 2008 |
| Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore S Gemma, G Campiani, S Butini, G Kukreja, BP Joshi, M Persico, ... Journal of medicinal chemistry 50 (4), 595-598, 2007 | 51 | 2007 |
| Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer: Enhancement of Anticoagulant Activity by a Single … N Borbone, M Bucci, G Oliviero, E Morelli, J Amato, V D’Atri, S D’Errico, ... Journal of Medicinal Chemistry 55 (23), 10716-10728, 2012 | 50 | 2012 |
| Identification of the first inhibitor of the GBP1: PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells M Andreoli, M Persico, A Kumar, N Orteca, V Kumar, A Pepe, ... Journal of medicinal chemistry 57 (19), 7916-7932, 2014 | 49 | 2014 |
| Specific Targeting of Peripheral Serotonin 5-HT3 Receptors. Synthesis, Biological Investigation, and Structure−Activity Relationships E Morelli, S Gemma, R Budriesi, G Campiani, E Novellino, C Fattorusso, ... Journal of medicinal chemistry 52 (11), 3548-3562, 2009 | 45 | 2009 |
| Insight into the mechanism of action of plakortins, simple 1, 2-dioxane antimalarials O Taglialatela-Scafati, E Fattorusso, A Romano, F Scala, V Barone, ... Organic & Biomolecular Chemistry 8 (4), 846-856, 2010 | 44 | 2010 |
| Antimalarials based on the dioxane scaffold of plakortin. A concise synthesis and SAR studies C Fattorusso, M Persico, N Basilico, D Taramelli, E Fattorusso, F Scala, ... Bioorganic & medicinal chemistry 19 (1), 312-320, 2011 | 34 | 2011 |
| Cationic porphyrins are tunable gatekeepers of the 20S proteasome AM Santoro, A Cunsolo, A D'Urso, D Sbardella, GR Tundo, C Ciaccio, ... Chemical science 7 (2), 1286-1297, 2016 | 32 | 2016 |
| Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue M Scuotto, M Persico, M Bucci, V Vellecco, N Borbone, E Morelli, ... Organic & Biomolecular Chemistry 12 (28), 5235-5242, 2014 | 32 | 2014 |
