| Prospective observational study on acute appendicitis worldwide (POSAW) M Sartelli, GL Baiocchi, S Di Saverio, F Ferrara, FM Labricciosa, ... World Journal of Emergency Surgery 13, 1-10, 2018 | 281 | 2018 |
| Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study) M Sartelli, FM Abu-Zidan, F Catena, EA Griffiths, S Di Saverio, R Coimbra, ... World journal of emergency surgery 10, 1-8, 2015 | 241 | 2015 |
| Physical activity during the early years: a systematic review of correlates and determinants DD Bingham, S Costa, T Hinkley, KA Shire, SA Clemes, SE Barber American journal of preventive medicine 51 (3), 384-402, 2016 | 171 | 2016 |
| Astroglial permissivity for neuritic outgrowth in neuron–astrocyte cocultures depends on regulation of laminin bioavailability S Costa, T Planchenault, C Charriere‐Bertrand, Y Mouchel, C Fages, ... Glia 37 (2), 105-113, 2002 | 135 | 2002 |
| Relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo‐caecal resection: an international snapshot audit 2015 European Society of Coloproctology Collaborating Group, ... Colorectal Disease 19 (8), e296-e311, 2017 | 134 | 2017 |
| Involvement of the kynurenine pathway in the pathogenesis of Parkinson’s disease CK Lim, FJ Fernandez-Gomez, N Braidy, C Estrada, C Costa, S Costa, ... Progress in Neurobiology 155, 76-95, 2017 | 127 | 2017 |
| Impact of plant-derived flavonoids on neurodegenerative diseases SL Costa, VDA Silva, C dos Santos Souza, CC Santos, I Paris, P Muñoz, ... Neurotoxicity research 30, 41-52, 2016 | 107 | 2016 |
| Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression BL Santos, MN Oliveira, PLC Coelho, BPS Pitanga, AB Da Silva, T Adelita, ... Chemico-biological interactions 242, 123-138, 2015 | 84 | 2015 |
| The flavonoid rutin and its aglycone quercetin modulate the microglia inflammatory profile improving antiglioma activity AB da Silva, PLC Coelho, M das Neves Oliveira, JL Oliveira, JAO Amparo, ... Brain, behavior, and immunity 85, 170-185, 2020 | 82 | 2020 |
| Quantifying the physical activity energy expenditure of commuters using a combination of global positioning system and combined heart rate and movement sensors S Costa, D Ogilvie, A Dalton, K Westgate, S Brage, J Panter Preventive medicine 81, 339-344, 2015 | 76 | 2015 |
| Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease NS Dourado, CS Souza, MMA De Almeida, A Bispo da Silva, ... Frontiers in Aging Neuroscience 12, 119, 2020 | 75 | 2020 |
| Antiproliferative, proapoptotic and morphogenic effects of the flavonoid rutin on human glioblastoma cells BL Santos, AR Silva, BPS Pitanga, CS Sousa, MS Grangeiro, ... Food chemistry 127 (2), 404-411, 2011 | 75 | 2011 |
| Alkaloids from Prosopis juliflora leaves induce glial activation, cytotoxicity and stimulate NO production. AMM Silva, AR Silva, AM Pinheiro, SRVB Freitas, VDA Silva, CS Souza, ... Toxicon 49 (5), 601-614, 2007 | 71 | 2007 |
| The flavonoid rutin induces astrocyte and microglia activation and regulates TNF-alpha and NO release in primary glial cell cultures AR Silva, AM Pinheiro, CS Souza, SRVB Freitas, V Vasconcellos, ... Cell Biology and Toxicology 24, 75-86, 2008 | 70 | 2008 |
| Effects of a novel synthetic retinoid on malignant glioma in vitro: inhibition of cell proliferation, induction of apoptosis and differentiation SL Costa, E Paillaud, C Fages, C Rochette-Egly, JL Plassat, H Jouault, ... European Journal of Cancer 37 (4), 520-530, 2001 | 67 | 2001 |
| Flavonoids inhibit angiogenic cytokine production by human glioma cells S Freitas, S Costa, C Azevedo, G Carvalho, S Freire, P Barbosa, E Velozo, ... Phytotherapy research 25 (6), 916-921, 2011 | 60 | 2011 |
| Biological monitoring of workers occupationally exposed to ethylene oxide LR Ribeiro, DMF Salvadori, ACC Rios, SL Costa, AD Tates, M Törnqvist, ... Mutation Research/Environmental Mutagenesis and Related Subjects 313 (1), 81-87, 1994 | 59 | 1994 |
| Development of methods to objectively identify time spent using active and motorised modes of travel to work: how do self-reported measures compare? J Panter, S Costa, A Dalton, A Jones, D Ogilvie international journal of behavioral nutrition and physical activity 11, 1-15, 2014 | 58 | 2014 |
| Genotoxicity and morphological changes induced by the alkaloid monocrotaline, extracted from Crotalaria retusa, in a model of glial cells JP Silva-Neto, RA Barreto, BPS Pitanga, CS Souza, VD Silva, AR Silva, ... Toxicon 55 (1), 105-117, 2010 | 54 | 2010 |
| A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo Y Nunez-Figueredo, J Ramírez-Sánchez, G Hansel, ENS Pires, N Merino, ... Neuropharmacology 85, 517-527, 2014 | 52 | 2014 |
