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Stephanie Portelli
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Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
F Coll, J Phelan, GA Hill-Cawthorne, MB Nair, K Mallard, S Ali, ...
Nature genetics 50 (2), 307-316, 2018
3622018
ThermoMutDB: a thermodynamic database for missense mutations
JS Xavier, TB Nguyen, M Karmarkar, S Portelli, PM Rezende, JPL Velloso, ...
Nucleic acids research 49 (D1), D475-D479, 2021
872021
Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis
S Portelli, JE Phelan, DB Ascher, TG Clark, N Furnham
Scientific reports 8 (1), 15356, 2018
822018
Exploring the structural distribution of genetic variation in SARS-CoV-2 with the COVID-3D online resource
S Portelli, M Olshansky, CHM Rodrigues, EN D’Souza, Y Myung, M Silk, ...
Nature genetics 52 (10), 999-1001, 2020
632020
Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches
S Portelli, Y Myung, N Furnham, SC Vedithi, DEV Pires, DB Ascher
Scientific reports 10 (1), 18120, 2020
502020
Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae
SC Vedithi, CHM Rodrigues, S Portelli, MJ Skwark, M Das, DB Ascher, ...
Computational and Structural Biotechnology Journal 18, 271-286, 2020
302020
Distinguishing between PTEN clinical phenotypes through mutation analysis
S Portelli, L Barr, AGC de Sá, DEV Pires, DB Ascher
Computational and Structural Biotechnology Journal 19, 3097-3109, 2021
272021
toxCSM: comprehensive prediction of small molecule toxicity profiles
AGC de Sá, Y Long, S Portelli, DEV Pires, DB Ascher
Briefings in Bioinformatics 23 (5), bbac337, 2022
262022
Combining structure and genomics to understand antimicrobial resistance
T Tunstall, S Portelli, J Phelan, TG Clark, DB Ascher, N Furnham
Computational and Structural Biotechnology Journal 18, 3377-3394, 2020
232020
Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase
Y Zhou, S Portelli, M Pat, CHM Rodrigues, TB Nguyen, DEV Pires, ...
Computational and Structural Biotechnology Journal 19, 5381-5391, 2021
212021
Definition of the immune evasion-replication interface of rabies virus P protein
J Zhan, AR Harrison, S Portelli, TB Nguyen, I Kojima, S Zheng, F Yan, ...
PLoS Pathogens 17 (7), e1009729, 2021
152021
Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin
AM Turner, L Li, IR Monk, JYH Lee, DJ Ingle, S Portelli, NL Sherry, N Isles, ...
Nature, 1-9, 2024
112024
Identifying the molecular drivers of ALS-implicated missense mutations
S Portelli, A Albanaz, DEV Pires, DB Ascher
Journal of Medical Genetics 60 (5), 484-490, 2023
92023
A metabolic signature for NADSYN1-dependent congenital NAD deficiency disorder
JO Szot, H Cuny, EMMA Martin, DZ Sheng, K Iyer, S Portelli, V Nguyen, ...
The Journal of clinical investigation 134 (4), 2024
82024
Exploring the effects of missense mutations on protein thermodynamics through structure-based approaches: findings from the CAGI6 challenges
CHM Rodrigues, S Portelli, DB Ascher
Human Genetics, 1-9, 2024
82024
AI-driven enhancements in drug screening and optimization
A Serghini, S Portelli, DB Ascher
Computational Drug Discovery and Design, 269-294, 2023
82023
COVID-3D: An online resource to explore the structural distribution of genetic variation in SARS-CoV-2 and its implication on therapeutic development
S Portelli, M Olshansky, CHM Rodrigues, EN D’Souza, Y Myung, M Silk, ...
bioRxiv, 2020.05. 29.124610, 2020
72020
Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
F Coll, J Phelan, GA Hill-Cawthorne, MB Nair, K Mallard, S Ali, ...
Nature genetics 50 (5), 764-764, 2018
72018
Exploring protein supersecondary structure through changes in protein folding, stability, and flexibility
DEV Pires, CHM Rodrigues, ATS Albanaz, M Karmakar, Y Myung, ...
Protein supersecondary structures: methods and protocols, 173-185, 2019
62019
Identifying Genotype–Phenotype Correlations via Integrative Mutation Analysis
E Airey, S Portelli, JS Xavier, YC Myung, M Silk, M Karmakar, JPL Velloso, ...
Artificial Neural Networks, 1-32, 2021
52021
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