| Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation AK Roseweir, AS Kauffman, JT Smith, KA Guerriero, K Morgan, ... Journal of Neuroscience 29 (12), 3920-3929, 2009 | 437 | 2009 |
| Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats JM Castellano, VM Navarro, R Fernández-Fernández, J Roa, E Vigo, ... Diabetes 55 (9), 2602-2610, 2006 | 307 | 2006 |
| Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals A Felip, S Zanuy, R Pineda, L Pinilla, M Carrillo, M Tena-Sempere, ... Molecular and cellular endocrinology 312 (1-2), 61-71, 2009 | 287 | 2009 |
| Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat VM Navarro, JM Castellano, SM McConkey, R Pineda, F Ruiz-Pino, ... American Journal of Physiology-Endocrinology and Metabolism 300 (1), E202-E210, 2011 | 277 | 2011 |
| Critical roles of kisspeptins in female puberty and preovulatory gonadotropin surges as revealed by a novel antagonist R Pineda, D Garcia-Galiano, A Roseweir, M Romero, ... Endocrinology 151 (2), 722-730, 2010 | 273 | 2010 |
| The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system J Roa, D Garcia-Galiano, L Varela, MA Sanchez-Garrido, R Pineda, ... Endocrinology 150 (11), 5016-5026, 2009 | 251 | 2009 |
| The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat D García-Galiano, VM Navarro, J Roa, F Ruiz-Pino, MA Sánchez-Garrido, ... Journal of Neuroscience 30 (23), 7783-7792, 2010 | 209 | 2010 |
| Novel expression and direct effects of adiponectin in the rat testis JE Caminos, R Nogueiras, F Gaytán, R Pineda, CR González, ... Endocrinology 149 (7), 3390-3402, 2008 | 180 | 2008 |
| Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies R Pineda, D Garcia-Galiano, MA Sanchez-Garrido, M Romero, ... American Journal of Physiology-Endocrinology and Metabolism 299 (1), E39-E46, 2010 | 168 | 2010 |
| Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty M Manfredi-Lozano, J Roa, F Ruiz-Pino, R Piet, D Garcia-Galiano, ... Molecular metabolism 5 (10), 844-857, 2016 | 156 | 2016 |
| Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation VM Navarro, MA Sanchez-Garrido, JM Castellano, J Roa, ... Endocrinology 150 (5), 2359-2367, 2009 | 152 | 2009 |
| Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testis D Garcia-Galiano, R Pineda, T Ilhan, JM Castellano, F Ruiz-Pino, ... Endocrinology 153 (4), 1959-1971, 2012 | 148 | 2012 |
| Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states J Roa, E Vigo, D Garcia-Galiano, JM Castellano, VM Navarro, R Pineda, ... American Journal of Physiology-Endocrinology and Metabolism 294 (6), E1088-E1096, 2008 | 126 | 2008 |
| Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and … R Pineda, D Garcia-Galiano, MA Sanchez-Garrido, M Romero, ... Endocrinology 151 (4), 1902-1913, 2010 | 115 | 2010 |
| Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences JM Castellano, VM Navarro, J Roa, R Pineda, MA Sanchez-Garrido, ... Endocrinology 150 (2), 784-794, 2009 | 101 | 2009 |
| Pattern of orexin expression and direct biological actions of orexin-A in rat testis ML Barreiro, R Pineda, F Gaytan, M Archanco, MA Burrell, JM Castellano, ... Endocrinology 146 (12), 5164-5175, 2005 | 97 | 2005 |
| Orexin 1 receptor messenger ribonucleic acid expression and stimulation of testosterone secretion by orexin-A in rat testis ML Barreiro, R Pineda, VM Navarro, M Lopez, JS Suominen, L Pinilla, ... Endocrinology 145 (5), 2297-2306, 2004 | 93 | 2004 |
| Physiological roles of the kisspeptin/GPR54 system in the neuroendocrine control of reproduction R Pineda, E Aguilar, L Pinilla, M Tena-Sempere Progress in brain research 181, 55-77, 2010 | 87 | 2010 |
| 60 years of neuroendocrinology: the posterior pituitary, from Geoffrey Harris to our present understanding G Leng, R Pineda, N Sabatier, M Ludwig Journal of Endocrinology 226 (2), T173-T185, 2015 | 84 | 2015 |
| Amygdala kisspeptin neurons: putative mediators of olfactory control of the gonadotropic axis R Pineda, F Plaisier, RP Millar, M Ludwig Neuroendocrinology 104 (3), 223-238, 2017 | 81 | 2017 |
MANUEL TENA-SEMPEREProfessor of Physiology, UNIVERSITY OF CORDOBAVerified email at uco.es
