Heather E. Wheeler
Heather E. Wheeler
Associate Professor, Loyola University Chicago
Dirección de correo verificada de luc.edu - Página principal
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A gene-based association method for mapping traits using reference transcriptome data
ER *Gamazon, HE *Wheeler, KP *Shah, SV Mozaffari, K Aquino-Michaels, ...
Nature genetics 47 (9), 1091, 2015
8712015
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ...
Nature communications 9 (1), 1-20, 2018
3152018
Cancer pharmacogenomics: strategies and challenges
HE Wheeler, ML Maitland, ME Dolan, NJ Cox, MJ Ratain
Nature Reviews Genetics 14 (1), 23-34, 2013
1922013
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia
B Diouf, KR Crews, G Lew, D Pei, C Cheng, J Bao, JJ Zheng, W Yang, ...
Jama 313 (8), 815-823, 2015
1892015
Genome-wide association and functional follow-up reveals new loci for kidney function
C Pattaro, A Köttgen, A Teumer, M Garnaas, CA Böger, C Fuchsberger, ...
PLoS Genet 8 (3), e1002584, 2012
1812012
Comprehensive audiometric analysis of hearing impairment and tinnitus after cisplatin-based chemotherapy in survivors of adult-onset cancer
RD *Frisina, HE *Wheeler, SD Fossa, SL Kerns, C Fung, HD Sesso, ...
Journal of Clinical Oncology 34 (23), 2712, 2016
1282016
Survey of the heritability and sparse architecture of gene expression traits across human tissues
HE Wheeler, KP Shah, J Brenner, T Garcia, K Aquino-Michaels, ...
PLoS genetics 12 (11), e1006423, 2016
1102016
Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation
HE Wheeler, ME Dolan
Pharmacogenomics 13 (1), 55-70, 2012
1082012
Genetics and genomics of human ageing
HE Wheeler, SK Kim
Philosophical Transactions of the Royal Society B: Biological Sciences 366 …, 2011
1032011
Integrating predicted transcriptome from multiple tissues improves association detection
AN Barbeira, M Pividori, J Zheng, HE Wheeler, DL Nicolae, HK Im
PLoS genetics 15 (1), e1007889, 2019
892019
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging
HE Wheeler, EJ Metter, T Tanaka, D Absher, J Higgins, JM Zahn, ...
PLoS Genet 5 (10), e1000685, 2009
822009
Relating human genetic variation to variation in drug responses
AG Madian, HE Wheeler, RB Jones, ME Dolan
Trends in genetics 28 (10), 487-495, 2012
762012
Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells
HE Wheeler, C Wing, SM Delaney, M Komatsu, ME Dolan
PloS one 10 (2), e0118020, 2015
732015
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function
DI Chasman, C Fuchsberger, C Pattaro, A Teumer, CA Böger, K Endlich, ...
Human molecular genetics 21 (24), 5329-5343, 2012
672012
Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy
LJ Leandro-García, S Leskelä, C Jara, H Gréen, E Åvall-Lundqvist, ...
Clinical Cancer Research 18 (16), 4441-4448, 2012
642012
Variants in WFS1 and other Mendelian deafness genes are associated with cisplatin-associated ototoxicity
HE Wheeler, ER Gamazon, RD Frisina, C Perez-Cervantes, O El Charif, ...
Clinical Cancer Research 23 (13), 3325-3333, 2017
552017
Genetic architecture of gene expression traits across diverse populations
LS Mogil, A Andaleon, A Badalamenti, SP Dickinson, X Guo, JI Rotter, ...
PLoS genetics 14 (8), e1007586, 2018
542018
Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
HE Wheeler, ER Gamazon, AL Stark, PH O'Donnell, LK Gorsic, RS Huang, ...
The pharmacogenomics journal 13 (1), 35-43, 2013
502013
Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of paclitaxel-induced sensory peripheral neuropathy
HE Wheeler, ER Gamazon, C Wing, UO Njiaju, C Njoku, RM Baldwin, ...
Clinical Cancer Research 19 (2), 491-499, 2013
492013
MetaXcan: summary statistics based gene-level association method infers accurate PrediXcan results
A Barbeira, KP Shah, JM Torres, HE Wheeler, ES Torstenson, T Edwards, ...
BioRxiv, 045260, 2016
432016
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Artículos 1–20