| An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea J Cortes, SF Haydock, GA Roberts, DJ Bevitt, PF Leadlay Nature 348 (6297), 176-178, 1990 | 833 | 1990 |
| The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin. T Schwecke, JF Aparicio, I Molnar, A König, LE Khaw, SF Haydock, ... Proceedings of the National Academy of Sciences 92 (17), 7839-7843, 1995 | 613 | 1995 |
| A chain initiation factor common to both modular and aromatic polyketide synthases C Bisang, PF Long, J Corte´ s, J Westcott, J Crosby, AL Matharu, RJ Cox, ... Nature 401 (6752), 502-505, 1999 | 363 | 1999 |
| Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage J Cortes, KEH Wiesmann, GA Roberts, MJB Brown, J Staunton, ... Science 268 (5216), 1487-1489, 1995 | 343 | 1995 |
| Engineering broader specificity into an antibiotic-producing polyketide synthase AFA Marsden, B Wilkinson, J Cortes, NJ Dunster, J Staunton, PF Leadlay Science 279 (5348), 199-202, 1998 | 330 | 1998 |
| A hybrid modular polyketide synthase obtained by domain swapping M Oliynyk, MJB Brown, J Cortés, J Staunton, PF Leadlay Chemistry & biology 3 (10), 833-839, 1996 | 287 | 1996 |
| 6‐Deoxyerythronolide‐B synthase 2 from Saccharopolyspora erythraea Cloning of the structural gene, sequence analysis and inferred domain structure of the … DJ Bevitt, J Cortes, SF Haydock, PF Leadlay European Journal of Biochemistry 204 (1), 39-49, 1992 | 246 | 1992 |
| Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family … SF Haydock, JA Dowson, N Dhillon, GA Roberts, J Cortes, PF Leadlay Molecular and General Genetics MGG 230, 120-128, 1991 | 206 | 1991 |
| Mutations in the conserved loop of human U5 snRNA generate use of novel cryptic 5′ splice sites in vivo. JJ Cortes, EJ Sontheimer, SD Seiwert, JA Steitz The EMBO journal 12 (13), 5181-5189, 1993 | 172 | 1993 |
| Analysis of seven genes from the eryAI –eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea S Gaisser, GA Böhm, J Cortés, PF Leadlay Molecular and General Genetics MGG 256, 239-251, 1997 | 155 | 1997 |
| Active-site residue, domain and module swaps in modular polyketide synthases F Del Vecchio, H Petkovic, SG Kendrew, L Low, B Wilkinson, R Lill, ... Journal of Industrial Microbiology and Biotechnology 30 (8), 489-494, 2003 | 150 | 2003 |
| Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues A Ranganathan, M Timoney, M Bycroft, J Cortés, IP Thomas, B Wilkinson, ... Chemistry & biology 6 (10), 731-741, 1999 | 150 | 1999 |
| VP7-2021: KEYNOTE-522: Phase III study of neoadjuvant pembrolizumab+ chemotherapy vs. placebo+ chemotherapy, followed by adjuvant pembrolizumab vs. placebo for early-stage TNBC P Schmid, J Cortes, R Dent, L Pusztai, H McArthur, S Kümmel, J Bergh, ... Annals of Oncology 32 (9), 1198-1200, 2021 | 146 | 2021 |
| Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea K Salah-Bey, M Doumith, JM Michel, S Haydock, J Cortes, PF Leadlay, ... Molecular and General Genetics MGG 257, 542-553, 1998 | 141 | 1998 |
| Polyketide synthesis in vitro on a modular polyketide synthase KEH Wiesmann, J Cortés, MJB Brown, AL Cutter, J Staunton, PF Leadlay Chemistry & Biology 2 (9), 583-589, 1995 | 137 | 1995 |
| Dissecting structural and functional diversity of the lantibiotic mersacidin AN Appleyard, S Choi, DM Read, A Lightfoot, S Boakes, A Hoffmann, ... Chemistry & biology 16 (5), 490-498, 2009 | 121 | 2009 |
| Engineering specificity of starter unit selection by the erythromycin‐producing polyketide synthase PF Long, CJ Wilkinson, CP Bisang, J Cortés, N Dunster, M Oliynyk, ... Molecular microbiology 43 (5), 1215-1225, 2002 | 117 | 2002 |
| Construction of new vectors for high-level expression in actinomycetes CJ Rowe, J Cortés, S Gaisser, J Staunton, PF Leadlay Gene 216 (1), 215-223, 1998 | 116 | 1998 |
| Molecular characterization of a gene from Saccharopolyspora erythraea (Streptomyces erythraeus) which is involved in erythromycin biosynthesis N Dhillon, RS Hale, J Cortes, PF Leadlay Molecular microbiology 3 (10), 1405-1414, 1989 | 116 | 1989 |
| Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase B Wilkinson, G Foster, BAM Rudd, NL Taylor, AP Blackaby, PJ Sidebottom, ... Chemistry & biology 7 (2), 111-117, 2000 | 109 | 2000 |
