| New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications SR Adams, RE Campbell, LA Gross, BR Martin, GK Walkup, Y Yao, ... Journal of the American Chemical Society 124 (21), 6063-6076, 2002 | 1191 | 2002 |
| Fluorescent sensors for Zn2+ based on a fluorescein platform: synthesis, properties and intracellular distribution SC Burdette, GK Walkup, B Spingler, RY Tsien, SJ Lippard Journal of the American Chemical Society 123 (32), 7831-7841, 2001 | 816 | 2001 |
| A New Cell-Permeable Fluorescent Probe for Zn2+ GK Walkup, SC Burdette, SJ Lippard, RY Tsien Journal of the American Chemical Society 122 (23), 5644-5645, 2000 | 689 | 2000 |
| ESKAPEing the labyrinth of antibacterial discovery R Tommasi, DG Brown, GK Walkup, JI Manchester, AA Miller Nature reviews Drug discovery 14 (8), 529-542, 2015 | 621 | 2015 |
| Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor DE Ehmann, H Jahić, PL Ross, RF Gu, J Hu, G Kern, GK Walkup, ... Proceedings of the National Academy of Sciences 109 (29), 11663-11668, 2012 | 583 | 2012 |
| Kinetics of avibactam inhibition against class A, C, and D β-lactamases DE Ehmann, H Jahić, PL Ross, RF Gu, J Hu, TF Durand-Réville, S Lahiri, ... Journal of Biological Chemistry 288 (39), 27960-27971, 2013 | 396 | 2013 |
| Exploiting polypeptide motifs for the design of selective Cu (II) ion chemosensors A Torrado, GK Walkup, B Imperiali Journal of the American Chemical Society 120 (3), 609-610, 1998 | 375 | 1998 |
| Fluorescent chemosensors for divalent zinc based on zinc finger domains. Enhanced oxidative stability, metal binding affinity, and structural and functional characterization GK Walkup, B Imperiali Journal of the American Chemical Society 119 (15), 3443-3450, 1997 | 255 | 1997 |
| Design and evaluation of a peptidyl fluorescent chemosensor for divalent zinc GK Walkup, B Imperiali Journal of the American Chemical Society 118 (12), 3053-3054, 1996 | 246 | 1996 |
| Translating slow-binding inhibition kinetics into cellular and in vivo effects GK Walkup, Z You, PL Ross, EKH Allen, F Daryaee, MR Hale, J O'donnell, ... Nature chemical biology 11 (6), 416-423, 2015 | 165 | 2015 |
| Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents AE Eakin, O Green, N Hales, GK Walkup, S Bist, A Singh, G Mullen, ... Antimicrobial agents and chemotherapy 56 (3), 1240-1246, 2012 | 135 | 2012 |
| Evaluation of pKa Estimation Methods on 211 Druglike Compounds J Manchester, G Walkup, O Rivin, Z You Journal of chemical information and modeling 50 (4), 565-571, 2010 | 121 | 2010 |
| Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC SD Lahiri, GK Walkup, JD Whiteaker, T Palmer, K McCormack, ... Journal of antimicrobial chemotherapy 70 (6), 1650-1658, 2015 | 118 | 2015 |
| Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases GS Basarab, GH Kern, J McNulty, JP Mueller, K Lawrence, ... Scientific reports 5 (1), 11827, 2015 | 99 | 2015 |
| Stereoselective synthesis of fluorescent α-amino acids containing oxine (8-hydroxyquinoline) and their peptide incorporation in chemosensors for divalent zinc GK Walkup, B Imperiali The Journal of Organic Chemistry 63 (19), 6727-6731, 1998 | 96 | 1998 |
| Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo SD Mills, AE Eakin, ET Buurman, JV Newman, N Gao, H Huynh, ... Antimicrobial agents and chemotherapy 55 (3), 1088-1096, 2011 | 92 | 2011 |
| Method for screening peptides for metal coordinating properties and fluorescent chemosensors derived therefrom B Imperiali, GK Walkup US Patent 6,083,758, 2000 | 63 | 2000 |
| Correction for interference by test samples in high-throughput assays AB Shapiro, GK Walkup, TA Keating SLAS Discovery 14 (8), 1008-1016, 2009 | 59 | 2009 |
| Peptidyl chemosensors incorporating a FRET mechanism for detection of Ni (II) DA Pearce, GK Walkup, B Imperiali Bioorganic & medicinal chemistry letters 8 (15), 1963-1968, 1998 | 56 | 1998 |
| Inhibition of Neisseria gonorrhoeae type II topoisomerases by the novel spiropyrimidinetrione AZD0914 G Kern, T Palmer, DE Ehmann, AB Shapiro, B Andrews, GS Basarab, ... Journal of Biological Chemistry 290 (34), 20984-20994, 2015 | 47 | 2015 |
