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Addison V Wright
Addison V Wright
Dirección de correo verificada de berkeley.edu
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Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering
AV Wright, JK Nuñez, JA Doudna
Cell 164 (1), 29-44, 2016
11602016
Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity
JK Nuñez, PJ Kranzusch, J Noeske, AV Wright, CW Davies, JA Doudna
Nature structural & molecular biology 21 (6), 528-534, 2014
5582014
Rational design of a split-Cas9 enzyme complex
AV Wright, SH Sternberg, DW Taylor, BT Staahl, JA Bardales, JE Kornfeld, ...
Proceedings of the National Academy of Sciences 112 (10), 2984-2989, 2015
3652015
Structures of the CRISPR genome integration complex
AV Wright, JJ Liu, GJ Knott, KW Doxzen, E Nogales, JA Doudna
Science 357 (6356), 1113-1118, 2017
1452017
Protecting genome integrity during CRISPR immune adaptation
AV Wright, JA Doudna
Nature structural & molecular biology 23 (10), 876-883, 2016
1152016
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
IE Ivanov, AV Wright, JC Cofsky, KDP Aris, JA Doudna, Z Bryant
Proceedings of the National Academy of Sciences 117 (11), 5853-5860, 2020
732020
Mutations in Cas9 enhance the rate of acquisition of viral spacer sequences during the CRISPR-Cas immune response
R Heler, AV Wright, M Vucelja, D Bikard, JA Doudna, LA Marraffini
Molecular cell 65 (1), 168-175, 2017
532017
A functional mini-integrase in a two-protein type VC CRISPR system
AV Wright, JY Wang, D Burstein, LB Harrington, D Paez-Espino, ...
Molecular cell 73 (4), 727-737. e3, 2019
312019
Spacer acquisition rates determine the immunological diversity of the type II CRISPR-Cas immune response
R Heler, AV Wright, M Vucelja, JA Doudna, LA Marraffini
Cell host & microbe 25 (2), 242-249. e3, 2019
232019
Heterodimeric Cas9 and methods of use thereof
SH Sternberg, JA Doudna, AV Wright
US Patent 11,208,638, 2021
112021
Aav vectors for gene editing
M Mohr, K Baney, A Sidore, C Fortuny, A Maroof, A Wright, BT Staahl, ...
US Patent App. 18/266,076, 2024
2024
Single-molecule analysis of DNA interrogation by Cas9 and Cas12a on supercoiled DNA
KDP Aris, J Cofsky, AV Wright, IE Ivanov, A Balaji, JA Doudna, Z Bryant
Biophysical Journal 121 (3), 288a, 2022
2022
Mechanisms of CRISPR-Cas Immune Adaptation
AV Wright
University of California, Berkeley, 2018
2018
Keeping CRISPR under control: how bacteria fight viruses without harming themselves
AV Wright
Nature 1, 14, 2017
2017
Heterodimeric cas9 and methods of use thereof
SH Sternberg, JA Doudna, AV WRIGHT
2016
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