| Endothelial-to-mesenchymal transition drives atherosclerosis progression PY Chen, L Qin, N Baeyens, G Li, T Afolabi, M Budatha, G Tellides, ... The Journal of clinical investigation 125 (12), 4514-4528, 2015 | 483 | 2015 |
| FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression PY Chen, L Qin, C Barnes, K Charisse, T Yi, X Zhang, R Ali, PP Medina, ... Cell reports 2 (6), 1684-1696, 2012 | 327 | 2012 |
| Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells CH Li, PY Chen, UM Chang, LS Kan, WH Fang, KS Tsai, SB Lin Life sciences 77 (3), 252-265, 2005 | 209 | 2005 |
| Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 200 | 2019 |
| FGF-dependent regulation of VEGF receptor 2 expression in mice M Murakami, LT Nguyen, K Hatanaka, W Schachterle, PY Chen, ... The Journal of clinical investigation 121 (7), 2668-2678, 2011 | 197 | 2011 |
| Smooth muscle cell reprogramming in aortic aneurysms PY Chen, L Qin, G Li, J Malagon-Lopez, Z Wang, S Bergaya, S Gujja, ... Cell stem cell 26 (4), 542-557. e11, 2020 | 138 | 2020 |
| Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium PY Chen, L Qin, G Tellides, M Simons Science signaling 7 (344), ra90-ra90, 2014 | 105 | 2014 |
| Endothelial-to-mesenchymal transition, vascular inflammation, and atherosclerosis PY Chen, MA Schwartz, M Simons Frontiers in cardiovascular medicine 7, 53, 2020 | 85 | 2020 |
| Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation PY Chen, L Qin, G Li, G Tellides, M Simons Scientific reports 6 (1), 33407, 2016 | 81 | 2016 |
| Smooth muscle FGF/TGF β cross talk regulates atherosclerosis progression PY Chen, L Qin, G Li, G Tellides, M Simons EMBO molecular medicine 8 (7), 712-728, 2016 | 81 | 2016 |
| Chronic mTOR activation induces a degradative smooth muscle cell phenotype G Li, M Wang, AW Caulk, NA Cilfone, S Gujja, L Qin, PY Chen, Z Chen, ... The Journal of clinical investigation 130 (3), 1233-1251, 2020 | 71 | 2020 |
| FRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor β-mediated regulation of vascular smooth muscle marker gene expression PY Chen, M Simons, R Friesel Journal of biological chemistry 284 (23), 15980-15992, 2009 | 58 | 2009 |
| Sef interacts with TAK1 and mediates JNK activation and apoptosis X Yang, D Kovalenko, RJ Nadeau, LK Harkins, J Mitchell, O Zubanova, ... Journal of Biological Chemistry 279 (37), 38099-38102, 2004 | 57 | 2004 |
| A role for extracellular and transmembrane domains of Sef in Sef-mediated inhibition of FGF signaling D Kovalenko, X Yang, PY Chen, RJ Nadeau, O Zubanova, K Pigeon, ... Cellular signalling 18 (11), 1958-1966, 2006 | 46 | 2006 |
| Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion G Li, L Qin, L Wang, X Li, AW Caulk, J Zhang, PY Chen, S Xin American Journal of Physiology-Heart and Circulatory Physiology 312 (6 …, 2017 | 44 | 2017 |
| Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia X Yang, LK Harkins, O Zubanova, A Harrington, D Kovalenko, RJ Nadeau, ... Developmental biology 321 (1), 64-76, 2008 | 44 | 2008 |
| TGFβR1 inhibition blocks the formation of stenosis in tissue-engineered vascular grafts DR Duncan, PY Chen, JT Patterson, YU Lee, N Hibino, M Cleary, Y Naito, ... Journal of the American College of Cardiology 65 (5), 512-514, 2015 | 37 | 2015 |
| Sprouty genes are expressed in osteoblasts and inhibit fibroblast growth factor-mediated osteoblast responses X Yang, JB Webster, D Kovalenko, RJ Nadeau, O Zubanova, PY Chen, ... Calcified tissue international 78, 233-240, 2006 | 33 | 2006 |
| When endothelial cells go rogue PY Chen, M Simons EMBO molecular medicine 8 (1), 1-2, 2016 | 26 | 2016 |
| The docking protein FRS2α is a critical regulator of VEGF receptors signaling PY Chen, L Qin, ZW Zhuang, G Tellides, I Lax, J Schlessinger, M Simons Proceedings of the National Academy of Sciences 111 (15), 5514-5519, 2014 | 25 | 2014 |
