Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis PK Parida, B Mahata, A Santra, S Chakraborty, Z Ghosh, S Raha, ... Cell Death & Disease 9 (5), 448, 2018 | 48 | 2018 |
Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase J Li, B Mahata, M Escobar, J Goell, K Wang, P Khemka, IB Hilton Nature Communications 12 (1), 896, 2021 | 46 | 2021 |
Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway M Kundu, B Mahata, A Banerjee, S Chakraborty, S Debnath, SS Ray, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1472-1489, 2016 | 35 | 2016 |
GBM derived gangliosides induce T cell apoptosis through activation of the caspase cascade involving both the extrinsic and the intrinsic pathway B Mahata, S Biswas, P Rayman, A Chahlavi, J Ko, A Bhattacharjee, YT Li, ... PloS one 10 (7), e0134425, 2015 | 33 | 2015 |
TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells B Mahata, A Banerjee, M Kundu, U Bandyopadhyay, K Biswas Scientific reports 5 (1), 9048, 2015 | 28 | 2015 |
Elevated histone H3 acetylation and loss of the Sp1–HDAC1 complex de-repress the GM2-synthase gene in renal cell carcinoma A Banerjee, B Mahata, A Dhir, TK Mandal, K Biswas Journal of Biological Chemistry 294 (3), 1005-1018, 2019 | 26 | 2019 |
Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer–promoter interactions K Wang, M Escobar, J Li, B Mahata, J Goell, S Shah, M Cluck, IB Hilton Nucleic Acids Research 50 (14), 7842-7855, 2022 | 15 | 2022 |
Compact engineered human transactivation modules enable potent and versatile synthetic transcriptional control B Mahata, J Li, A Cabrera, DA Brenner, RS Guerra-Resendez, J Goell, ... BioRxiv, 2022-03, 2022 | 9* | 2022 |
Eriodictyol mediated selective targeting of the TNFR1/FADD/TRADD axis in cancer cells induce apoptosis and inhibit tumor progression and metastasis S Debnath, A Sarkar, DD Mukherjee, S Ray, B Mahata, T Mahata, ... Translational Oncology 21, 101433, 2022 | 7 | 2022 |
Generation of stable knockout mammalian cells by TALEN-mediated locus-specific gene editing B Mahata, K Biswas In Vitro Mutagenesis: Methods and Protocols, 107-120, 2017 | 4 | 2017 |
Persistent tailoring of MSC activation through genetic priming MA Beauregard, GC Bedford, DA Brenner, LD Sanchez Solis, ... bioRxiv, 2024.02. 01.578489, 2024 | | 2024 |
Combining compact human protein domains with CRISPR systems for robust gene activation B Mahata, IB Hilton NATURE METHODS 20 (11), 1635-1636, 2023 | | 2023 |
Engineered multipartite transcriptional effectors sourced from human protein domains IH Barun MAHATA, Jacob GOELL | | 2023 |
Ganglioside GM2 mediated tumor growth, progression, and metastasis involves YAP-dependent transcriptional program B Mahata, A Sarkar, E Khamrui, S Chakraborty, Z Ghosh, K Biswas Cancer Research 78 (13_Supplement), 1110-1110, 2018 | | 2018 |
Study the role and elucidate the mechanism of tumor derived gangliosides in tumor growth progression and metastasis in syngenic mouse tumor model B Mahata Kolkata, 2017 | | 2017 |
GM2 mediates tumor cell migration and induces EMT through involvement of the integrin signaling machinery and targeting YAP, a major component of the HIPPO signaling pathway M Kundu, B Mahata, A Banerjee, S Debnath, K Biswas Cancer Research 76 (14_Supplement), 5146-5146, 2016 | | 2016 |
Research briefing B Mahata, IB Hilton | | |