| MicroRNA silencing for cancer therapy targeted to the tumour microenvironment CJ Cheng, R Bahal, IA Babar, Z Pincus, F Barrera, C Liu, A Svoronos, ... Nature 518 (7537), 107, 2015 | 895 | 2015 |
| In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates K Musunuru, AC Chadwick, T Mizoguchi, SP Garcia, JE DeNizio, ... Nature 593 (7859), 429-434, 2021 | 642 | 2021 |
| Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma IA Babar, CJ Cheng, CJ Booth, X Liang, JB Weidhaas, WM Saltzman, ... Proceedings of the National Academy of Sciences 109 (26), E1695-E1704, 2012 | 592 | 2012 |
| A holistic approach to targeting disease with polymeric nanoparticles CJ Cheng, GT Tietjen, JK Saucier-Sawyer, WM Saltzman Nature reviews Drug discovery 14 (4), 239-247, 2015 | 510 | 2015 |
| Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery J Zhou, J Liu, CJ Cheng, TR Patel, CE Weller, JM Piepmeier, Z Jiang, ... Nature materials 11 (1), 82, 2012 | 419 | 2012 |
| MiR-34a silences c-SRC to attenuate tumor growth in triple-negative breast cancer BD Adams, VB Wali, CJ Cheng, S Inukai, CJ Booth, S Agarwal, DL Rimm, ... Cancer research 76 (4), 927-939, 2016 | 194 | 2016 |
| In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery R Bahal, NA McNeer, E Quijano, Y Liu, P Sulkowski, A Turchick, YC Lu, ... Nature communications 7, 13304, 2016 | 180 | 2016 |
| Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides CJ Cheng, WM Saltzman Biomaterials 32 (26), 6194-6203, 2011 | 158 | 2011 |
| Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA KH Asrani, JD Farelli, MR Stahley, RL Miller, CJ Cheng, RR Subramanian, ... RNA biology 15 (6), 756-762, 2018 | 132 | 2018 |
| Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing CJ Cheng, WM Saltzman Molecular pharmaceutics 9 (5), 1481-1488, 2012 | 121 | 2012 |
| Surface modified poly (β amino ester)-containing nanoparticles for plasmid DNA delivery RJ Fields, CJ Cheng, E Quijano, C Weller, N Kristofik, N Duong, ... Journal of Controlled Release 164 (1), 41-48, 2012 | 108 | 2012 |
| miR-155 is essential for inflammation-induced hippocampal neurogenic dysfunction ME Woodbury, RW Freilich, CJ Cheng, H Asai, S Ikezu, JD Boucher, ... Journal of Neuroscience 35 (26), 9764-9781, 2015 | 106 | 2015 |
| Systemic delivery of blood–brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue JK Saucier-Sawyer, Y Deng, YE Seo, CJ Cheng, J Zhang, E Quijano, ... Journal of drug targeting 23 (7-8), 736-749, 2015 | 102 | 2015 |
| Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo NA McNeer, EB Schleifman, A Cuthbert, M Brehm, A Jackson, C Cheng, ... Gene therapy 20 (6), 658, 2013 | 97 | 2013 |
| Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation J Devalliere, WG Chang, JW Andrejecsk, P Abrahimi, CJ Cheng, ... The FASEB Journal 28 (2), 908-922, 2014 | 92 | 2014 |
| The duality of oncomiR addiction in the maintenance and treatment of cancer CJ Cheng, FJ Slack Cancer journal (Sudbury, Mass.) 18 (3), 232, 2012 | 86 | 2012 |
| Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer DT Martin, CJ Hoimes, HZ Kaimakliotis, CJ Cheng, K Zhang, J Liu, ... Nanomedicine: Nanotechnology, Biology and Medicine 9 (8), 1124-1134, 2013 | 67 | 2013 |
| A “top-down” approach to actuate poly (amine-co-ester) terpolymers for potent and safe mRNA delivery Y Jiang, A Gaudin, J Zhang, T Agarwal, E Song, AC Kauffman, GT Tietjen, ... Biomaterials 176, 122-130, 2018 | 66 | 2018 |
| GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy LN Kasiewicz, S Biswas, A Beach, H Ren, C Dutta, AM Mazzola, E Rohde, ... Nature Communications 14 (1), 2776, 2023 | 65 | 2023 |
| Canonical and non-canonical barriers facing antimiR cancer therapeutics C J Cheng, W Mark Saltzman, F J Slack Current medicinal chemistry 20 (29), 3582-3593, 2013 | 57 | 2013 |
