| Redox Signaling Mediated by the Thioredoxin and Glutathione Systems in the Central Nervous System DJL Mr. Xiaoyuan Ren, Dr. Lili Zou, Dr. Xu Zhang, Dr. Vasco Branco, Dr. Jun ... Antioxidants & Redox Signaling, 2017 | 289 | 2017 |
| Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning CML Carvalho, J Lu, X Zhang, ESJ Arnér, A Holmgren The FASEB Journal 25 (1), 370-381, 2011 | 135 | 2011 |
| A new mechanism of action for the anticancer drug mitomycin C: mechanism-based inhibition of thioredoxin reductase MM Paz, X Zhang, J Lu, A Holmgren Chemical research in toxicology 25 (7), 1502-1511, 2012 | 134 | 2012 |
| Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system Y Du, H Zhang, X Zhang, J Lu, A Holmgren Journal of Biological Chemistry 288 (45), 32241-32247, 2013 | 114 | 2013 |
| Glutaredoxin 2 reduces both thioredoxin 2 and thioredoxin 1 and protects cells from apoptosis induced by auranofin and 4-hydroxynonenal H Zhang, Y Du, X Zhang, J Lu, A Holmgren Antioxidants & Redox Signaling 21 (5), 669-681, 2014 | 91 | 2014 |
| Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes X Zhang, Y Zheng, LE Fried, Y Du, SJ Montano, A Sohn, B Lefkove, ... Free Radical Biology and Medicine 50 (7), 811-820, 2011 | 70 | 2011 |
| Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer’s disease T Nakamura, C Oh, L Liao, X Zhang, KM Lopez, D Gibbs, AK Deal, ... Science 371 (6526), eaaw0843, 2021 | 57 | 2021 |
| Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration T Nakamura, C Oh, X Zhang, SA Lipton Free Radical Biology and Medicine 172, 562-577, 2021 | 43 | 2021 |
| Control of mammalian brain aging by the unfolded protein response (UPR) F Cabral-Miranda, G Tamburini, G Martinez, D Medinas, Y Gerakis, ... Biorxiv, 2020.04. 13.039172, 2020 | 33* | 2020 |
| S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD E Pirie, C Oh, X Zhang, X Han, P Cieplak, HR Scott, AK Deal, S Ghatak, ... Proceedings of the National Academy of Sciences 118 (11), e2021368118, 2021 | 32 | 2021 |
| Oxidation of structural cysteine residues in thioredoxin 1 by aromatic arsenicals enhances cancer cell cytotoxicity caused by the inhibition of thioredoxin reductase 1 X Zhang, J Lu, X Ren, Y Du, Y Zheng, PV Ioannou, A Holmgren Free Radical Biology and Medicine 89, 192-200, 2015 | 32 | 2015 |
| Protein transnitrosylation signaling networks contribute to inflammaging and neurodegenerative disorders T Nakamura, C Oh, X Zhang, SR Tannenbaum, SA Lipton Antioxidants & redox signaling 35 (7), 531-550, 2021 | 23 | 2021 |
| Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection C Oh, T Nakamura, N Beutler, X Zhang, J Piña-Crespo, M Talantova, ... Nature chemical biology 19 (3), 275-283, 2023 | 17 | 2023 |
arne holmgrenprofessor i biokemi , Karolinska InstitutetVerified email at ki.se
