Gabriel Piedrafita
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The widespread role of non-enzymatic reactions in cellular metabolism
MA Keller, G Piedrafita, M Ralser
Current Opinion in Biotechnology 34, 153-161, 2015
882015
Allele-specific gene expression is widespread across the genome and biological processes
R Palacios, E Gazave, J Goñi, G Piedrafita, O Fernando, A Navarro, ...
PLoS One 4 (1), e4150, 2009
602009
The impact of non-enzymatic reactions and enzyme promiscuity on cellular metabolism during (oxidative) stress conditions
G Piedrafita, MA Keller, M Ralser
Biomolecules 5 (3), 2101-2122, 2015
582015
A simple self-maintaining metabolic system: robustness, autocatalysis, bistability
G Piedrafita, F Montero, F Morán, ML Cardenas, A Cornish-Bowden
PLoS Comput Biol 6 (8), e1000872, 2010
572010
Nonenzymatic gluconeogenesis-like formation of fructose 1, 6-bisphosphate in ice
CB Messner, PC Driscoll, G Piedrafita, MFL De Volder, M Ralser
Proceedings of the National Academy of Sciences 114 (28), 7403-7407, 2017
262017
Epidermal tissue adapts to restrain progenitors carrying clonal p53 mutations
K Murai, G Skrupskelyte, G Piedrafita, M Hall, V Kostiou, SH Ong, T Nagy, ...
Cell Stem Cell 23 (5), 687-699. e8, 2018
242018
Viability conditions for a compartmentalized protometabolic system: a semi-empirical approach
G Piedrafita, K Ruiz-Mirazo, PA Monnard, A Cornish-Bowden, F Montero
PLos one 7 (6), e39480, 2012
232012
Outcompeting p53-mutant cells in the normal esophagus by redox manipulation
D Fernandez-Antoran, G Piedrafita, K Murai, SH Ong, A Herms, C Frezza, ...
Cell stem cell 25 (3), 329-341. e6, 2019
222019
Permeability-driven selection in a semi-empirical protocell model: the roots of prebiotic systems evolution
G Piedrafita, PA Monnard, F Mavelli, K Ruiz-Mirazo
Scientific reports 7 (1), 1-10, 2017
132017
Size matters: Influence of stochasticity on the self-maintenance of a simple model of metabolic closure
G Piedrafita, A Cornish-Bowden, F Moran, F Montero
Journal of theoretical biology 300, 143-151, 2012
132012
Simulating a model of metabolic closure
A Cornish-Bowden, G Piedrafita, F Morán, ML Cárdenas, F Montero
Biological Theory 8 (4), 383-390, 2013
122013
Stochastic simulations of mixed-lipid compartments: From self-assembling vesicles to self-producing protocells
K Ruiz-Mirazo, G Piedrafita, F Ciriaco, F Mavelli
Software Tools and Algorithms for Biological Systems, 689-696, 2011
122011
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice
G Piedrafita, V Kostiou, A Wabik, B Colom, D Fernandez-Antoran, ...
Nature communications 11 (1), 1-15, 2020
7*2020
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ...
Nature Genetics, 1-11, 2020
52020
On the transition from prebiotic to proto-biological membranes: from ‘self-assembly’to ‘self-production’
G Piedrafita, F Mavelli, F Morán, K Ruiz-Mirazo
European Conference on Artificial Life, 256-264, 2009
52009
Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis
VR Senthivel, M Sturrock, G Piedrafita, M Isalan
Scientific reports 6 (1), 1-15, 2016
42016
¿Qué es la vida?
ML Cárdenas, G Piedrafita, F Montero, A Cornish-Bowden
SEBBM 175, 14-16, 2013
32013
Mutations in Non-Tumoral Human Urothelium: Disease Prelude or Epilogue?
G Piedrafita, LC Fernández, FX Real
Bladder Cancer, 1-12, 2020
2020
Single amino acid-promoted reactions link a non-enzymatic chemical network to the early evolution of enzymatic pentose phosphate pathway
G Piedrafita, SJ Varma, C Castro, CB Messner, L Szyrwiel, JL Griffin, ...
BioRxiv, 2020
2020
High-Throughput Kinetic Screening of Non-Enzymatic Metabolic Conversions Driven by Single Amino Acids
G Piedrafita, C Castro, C Messner, JL Griffin, M Ralser
LPICo 1967, 4213, 2017
2017
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Artículos 1–20