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Wen Gu
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Metabolic heterogeneity confers differences in melanoma metastatic potential
A Tasdogan, B Faubert, V Ramesh, JM Ubellacker, B Shen, A Solmonson, ...
Nature 577 (7788), 115-120, 2020
3472020
Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state
W Gu, X Gaeta, A Sahakyan, AB Chan, CS Hong, R Kim, D Braas, K Plath, ...
Cell stem cell 19 (4), 476-490, 2016
2612016
MCT1 modulates cancer cell pyruvate export and growth of tumors that co-express MCT1 and MCT4
CS Hong, NA Graham, W Gu, CE Camacho, V Mah, EL Maresh, M Alavi, ...
Cell reports 14 (7), 1590-1601, 2016
2072016
Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers
F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ...
Cell metabolism 28 (3), 369-382. e5, 2018
1582018
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer
J Kim, HM Lee, F Cai, B Ko, C Yang, EL Lieu, N Muhammad, S Rhyne, ...
Nature metabolism 2 (12), 1401-1412, 2020
862020
Compartmentalized metabolism supports midgestation mammalian development
A Solmonson, B Faubert, W Gu, A Rao, MA Cowdin, I Menendez-Montes, ...
Nature 604 (7905), 349-353, 2022
562022
Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration
L Qi, MS Martin-Sandoval, S Merchant, W Gu, M Eckhardt, TP Mathews, ...
Cell Stem Cell 28 (11), 1982-1999. e8, 2021
402021
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ...
Proceedings of the National Academy of Sciences 119 (6), e2120617119, 2022
392022
In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors
P Pachnis, Z Wu, B Faubert, A Tasdogan, W Gu, S Shelton, A Solmonson, ...
Science Advances 8 (35), eabn9550, 2022
172022
Development of novel mitochondrial pyruvate carrier inhibitors to treat hair loss
X Liu, AA Flores, L Situ, W Gu, H Ding, HR Christofk, WE Lowry, ME Jung
Journal of medicinal chemistry 64 (4), 2046-2063, 2021
172021
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids
M Watanabe, JE Buth, JR Haney, N Vishlaghi, F Turcios, LS Elahi, W Gu, ...
Stem Cell Reports 17 (10), 2220-2238, 2022
132022
A short isoform of spermatogenic enzyme GAPDHS functions as a metabolic switch and limits metastasis in melanoma
JG Gill, SN Leef, V Ramesh, MS Martin-Sandoval, AD Rao, L West, S Muh, ...
Cancer research 82 (7), 1251-1266, 2022
82022
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids
M Watanabe, JR Haney, N Vishlaghi, F Turcios, JE Buth, W Gu, AJ Collier, ...
bioRxiv, 2019.12. 13.875773, 2019
82019
L-2-hydroxyglutaric aciduria–review of literature and case series
S Ahmed, A Siddiqui, RJ DeBerardinis, M Ni, WG Lai, F Cai, HS Vu, ...
Annals of Medicine and Surgery 85 (4), 712-717, 2023
22023
Electron transport inhibition increases cellular dependence on purine transport and salvage
Z Wu, D Bezwada, RC Harris, C Pan, PT Nguyen, B Faubert, L Cai, F Cai, ...
bioRxiv, 2023.05. 11.540429, 2023
22023
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples
F Cai, D Bezwada, L Cai, R Mahar, Z Wu, MC Chang, P Pachnis, C Yang, ...
Cell metabolism 35 (10), 1830-1843. e5, 2023
12023
G6PD deficiency sensitizes metastasizing melanoma cells to oxidative stress and glutaminolysis
AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ...
bioRxiv, 2021.11. 11.468286, 2021
12021
An interactive web application for exploring human plasma and fibroblast metabolomics data from patients with inborn errors of metabolism
L Cai, V Hieu, W Gu, H Chen, J Franklin, L Abou Haidar, Z Wu, C Pan, ...
bioRxiv, 2023.12. 11.571124, 2023
2023
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