Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene V Sauzeau, JM Carvajal-González, AS Riolobos, MA Sevilla, ... Journal of biological chemistry 286 (4), 2896-2909, 2011 | 73 | 2011 |
The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops M Menacho-Marquez, R García-Escudero, V Ojeda, A Abad, P Delgado, ... PLoS biology 11 (7), e1001615, 2013 | 63 | 2013 |
A paradoxical tumor-suppressor role for the Rac1 exchange factor Vav1 in T cell acute lymphoblastic leukemia J Robles-Valero, LF Lorenzo-Martín, M Menacho-Marquez, ... Cancer Cell 32 (5), 608-623. e9, 2017 | 42 | 2017 |
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma LF Lorenzo-Martín, N Fernández-Parejo, M Menacho-Márquez, ... Nature Communications 11 (1), 4788, 2020 | 34 | 2020 |
The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development RM Larive, A Abad, CM Cardaba, T Hernández, M Cañamero, E de Álava, ... Molecular biology of the cell 23 (12), 2373-2387, 2012 | 31 | 2012 |
Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis S Rodríguez-Fdez, LF Lorenzo-Martín, I Fernández-Pisonero, B Porteiro, ... Nature communications 11 (1), 5808, 2020 | 21 | 2020 |
Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis J Robles‐Valero, L Fernández‐Nevado, LF Lorenzo‐Martín, M Cuadrado, ... The EMBO journal 40 (22), e108125, 2021 | 13 | 2021 |
Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions LF Lorenzo-Martín, M Menacho-Márquez, S Fabbiano, O Al-Massadi, ... Journal of Endocrinology 240 (3), 483-496, 2019 | 11 | 2019 |
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors I Fernandez-Pisonero, L Clavaín, J Robles-Valero, LF Lorenzo-Martín, ... Cell Reports 38 (11), 2022 | 10 | 2022 |
Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor LF Lorenzo-Martín, S Rodriguez-Fdez, S Fabbiano, A Abad, ... Oncogene 39 (28), 5098-5111, 2020 | 10 | 2020 |
Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors L Clavaín, I Fernández-Pisonero, N Movilla, LF Lorenzo-Martín, B Nieto, ... Oncogene 42 (5), 389-405, 2023 | 4 | 2023 |
The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function LF Lorenzo-Martín, M Menacho-Márquez, N Fernández-Parejo, ... Oncogene 41 (24), 3341-3354, 2022 | 4 | 2022 |
Characterization of the spectrum of trivalent VAV1‐mutation‐driven tumours using a gene‐edited mouse model J Robles‐Valero, L Fernández‐Nevado, M Cuadrado, LF Lorenzo‐Martín, ... Molecular Oncology 16 (19), 3533-3553, 2022 | 3 | 2022 |
Hematopoietic cells influence vascular development in the retina B Asare-Bediako, Y Adu-Agyeiwaah, A Abad, S Li Calzi, JL Floyd, ... Cells 11 (20), 3207, 2022 | 2 | 2022 |
Distinct roles of vav family members in adaptive and innate immune models of arthritis J Conde, I Fernández-Pisonero, M Cuadrado, A Abad, J Robles-Valero, ... Biomedicines 9 (6), 695, 2021 | 1 | 2021 |
Characterization of the spectrum of trivalent VAV1 mutation-driven tumors using a gene-edited mouse model [Dataset] J Robles-Valero, L Fernández-Nevado, M Cuadrado, L Lorenzo-Martín, ... GEO-Gene Expression Omnibus, 2022 | | 2022 |
An unexpected tumor suppresor role for the Rac1 exchange factor Vav1 in T cell acute lymphoblastic leukemia J Robles-Valero, L Lorenzo-Martín, M Menacho-Márquez, A Abad, ... Sociedad Española de Bioquímica y Biología Molecular, 2016 | | 2016 |
THE TRANSCRIPTIONAL FACTOR Ahr CONTROLS CARDIOVASCULAR AND RESPIRATORY FUNCTIONS BY REGULATING THE EXPRESSION OF THE Vav3 PROTO-ONCOGENE V Sauzeau, JM Carvajal-González, AS Riolobos, MA Sevilla, ... | | 2010 |
SUPPLEMENTARY INFORMATIONa RM Larive, A Abad, CM Cardaba, T Hernández, M Cañamero, E de Álava, ... | | |