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Leon Harrington
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Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate
L Harrington, S Cheley, LT Alexander, S Knapp, H Bayley
Proceedings of the National Academy of Sciences 110 (47), E4417-E4426, 2013
572013
Single-molecule interrogation of a bacterial sugar transporter allows the discovery of an extracellular inhibitor
L Kong, L Harrington, Q Li, S Cheley, BG Davis, H Bayley
Nature chemistry 5 (8), 651-659, 2013
502013
Single-molecule protein phosphorylation and dephosphorylation by nanopore enzymology
L Harrington, LT Alexander, S Knapp, H Bayley
ACS nano 13 (1), 633-641, 2018
492018
Pim kinase inhibitors evaluated with a single‐molecule engineered nanopore sensor
L Harrington, LT Alexander, S Knapp, H Bayley
Angewandte Chemie 127 (28), 8272-8277, 2015
412015
De novo design of a reversible phosphorylation-dependent switch for membrane targeting
L Harrington, JM Fletcher, T Heermann, DN Woolfson, P Schwille
Nature Communications 12 (1), 1472, 2021
282021
Reverse and forward engineering of protein pattern formation
S Kretschmer, L Harrington, P Schwille
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
102018
Wrestling with native chemical ligation
H Bayley, S Cheley, L Harrington, R Syeda
ACS chemical biology 4 (12), 983-985, 2009
102009
Probing biomolecular interactions by a pattern-forming peptide–conjugate sensor
T Heermann, HG Franquelim, P Glock, L Harrington, P Schwille
Bioconjugate chemistry 32 (1), 172-181, 2020
12020
Nanopore Enzymology to Study Protein Kinases and Their Inhibition by Small Molecules
L Harrington, LT Alexander, S Knapp, H Bayley
Nanopore Technology: Methods and Protocols, 95-114, 2021
2021
Innentitelbild: Pim Kinase Inhibitors Evaluated with a Single‐Molecule Engineered Nanopore Sensor (Angew. Chem. 28/2015)
L Harrington, LT Alexander, S Knapp, H Bayley
Angewandte Chemie 127 (28), 8114-8114, 2015
2015
Inside Cover: Pim Kinase Inhibitors Evaluated with a Single‐Molecule Engineered Nanopore Sensor (Angew. Chem. Int. Ed. 28/2015)
L Harrington, LT Alexander, S Knapp, H Bayley
Angewandte Chemie International Edition 54 (28), 8002-8002, 2015
2015
Electrostatically Enhanced Association of a Pim Kinase Substrate Revealed by Stochastic Detection
L Harrington, S Cheley, LT Alexander, S Knapp, H Bayley
Biophysical Journal 106 (2), 18a, 2014
2014
Engineering Pores for Stochastic Sensing and Single Molecule Studies
LEO Harrington
University of Oxford, 2012
2012
PNAS Plus Significance Statements
L Harrington, S Cheley, LT Alexander, S Knapp, H Bayley
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Articles 1–14