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Giridhar Murlidharan [Giri]
Giridhar Murlidharan [Giri]
Director, Translational Science, Affinia Therapeutics
Verified email at affiniatx.com
Title
Cited by
Cited by
Year
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
H Mestre, LM Hablitz, ALR Xavier, W Feng, W Zou, T Pu, H Monai, ...
Elife 7, e40070, 2018
4642018
Biology of adeno-associated viral vectors in the central nervous system
G Murlidharan, RJ Samulski, A Asokan
Frontiers in molecular neuroscience 7, 76, 2014
2032014
Mapping the structural determinants required for AAVrh. 10 transport across the blood-brain barrier
BH Albright, CM Storey, G Murlidharan, RMC Rivera, GE Berry, ...
Molecular Therapy 26 (2), 510-523, 2018
852018
Glymphatic fluid transport controls paravascular clearance of AAV vectors from the brain
G Murlidharan, A Crowther, RA Reardon, J Song, A Asokan
JCI insight 1 (14), 2016
832016
CNS-restricted transduction and CRISPR/Cas9-mediated gene deletion with an engineered AAV vector
G Murlidharan, K Sakamoto, L Rao, T Corriher, D Wang, G Gao, ...
Molecular Therapy-Nucleic Acids 5, 2016
752016
AAV gene therapy for MPS1-associated corneal blindness
M Vance, T Llanga, W Bennett, K Woodard, G Murlidharan, N Chungfat, ...
Scientific reports 6 (1), 22131, 2016
562016
Unique glycan signatures regulate adeno-associated virus tropism in the developing brain
G Murlidharan, T Corriher, HT Ghashghaei, A Asokan
Journal of virology 89 (7), 3976-3987, 2015
442015
The Golgi calcium ATPase pump plays an essential role in adeno-associated virus trafficking and transduction
VJ Madigan, GE Berry, TO Tyson, D Nardone-White, J Ark, ZC Elmore, ...
Journal of virology 94 (21), 10.1128/jvi. 01604-20, 2020
172020
Aquaporin-4-dependent glymphatic solute transport in the rodent brain. eLife 7
H Mestre, LM Hablitz, AL Xavier, W Feng, W Zou, T Pu, H Monai, ...
132018
30. Modulation of intracellular calcium enhances AAV transduction in the CNS
G Berry, G Murlidharan, A Asokan
Molecular Therapy 24, S14, 2016
82016
Compositions and methods for delivery of aav
DWY Sah, H Patzke, T Carter, J Hou, G Murlidharan
US Patent App. 17/055,416, 2021
52021
Methods and compositions for targeted gene transfer
A Asokan, G Murlidharan, S Shen
US Patent 10,907,176, 2021
52021
Compositions and methods for delivery of aav
G Murlidharan, DWY Sah, H Patzke, T Carter, J Hou, K Adachi, A Ren
US Patent App. 17/284,499, 2021
22021
55. Aquaporins and CSF flux are critical determinants of AAV mediated CNS gene Transfer
G Murlidharan, A Asokan
Molecular Therapy 24, S25, 2016
22016
Efficacy of a vectorized anti‐tau antibody using systemic dosing of a blood brain barrier penetrant AAV capsid in mouse models of tauopathies
W Liu, J Holth, M Paranjpe, XQ Ren, Y Shu, G Murlidharan, C Chung, ...
Alzheimer's & Dementia 17, e053341, 2021
12021
AAV gene delivery of an anti-Tau antibody using a novel blood brain barrier penetrant capsid in wild type and P301S tauopathy mice
TA Carter, W Liu, G Murlidharan, Y Shu, M Paranjpe, C Huang, ...
HUMAN GENE THERAPY 28 (12), A80-A80, 2017
12017
Discovery of a Neurotropic Footprint That Enables AAV Transport Across the Blood-Brain Barrier
B Albright, C Storey, G Murlidharan, RC Rivera, A Asokan
MOLECULAR THERAPY 25 (5), 230-231, 2017
12017
14. Next Generation AAV Vectors for Limiting Systemic Leakage and Improving Safety Following CNS Administration
G Murlidharan, L Rao, D Wang, T Corriher, K Seok-Oh, G Gao, ...
Molecular Therapy 23, S6, 2015
12015
42. Differential transduction profiles of AAV vectors in a mouse model of human glycosylation
L Rao, BH Albright, T Corriher, G Murlidharan, A Asokan
Molecular Therapy 23, S18-S19, 2015
12015
Compositions for and methods of improving fluid flux in the brain
A Asokan, A Mitchell-Dick, G Murlidharan, RC Rivera
US Patent App. 18/272,208, 2024
2024
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