Alec S.T. Smith
Cited by
Cited by
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs
C Oleaga, C Bernabini, AST Smith, B Srinivasan, M Jackson, W McLamb, ...
Scientific reports 6 (1), 1-17, 2016
Microfabricated mammalian organ systems and their integration into models of whole animals and humans
JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler
Lab on a Chip 13 (7), 1201-1212, 2013
How multi-organ microdevices can help foster drug development
MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler
Advanced drug delivery reviews 69, 158-169, 2014
Nanotopography-induced structural anisotropy and sarcomere development in human cardiomyocytes derived from induced pluripotent stem cells
D Carson, M Hnilova, X Yang, CL Nemeth, JH Tsui, AST Smith, A Jiao, ...
ACS applied materials & interfaces 8 (34), 21923-21932, 2016
Biomimetic 3D tissue models for advanced high-throughput drug screening
KH Nam, AST Smith, S Lone, S Kwon, DH Kim
Journal of laboratory automation 20 (3), 201-215, 2015
Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening
AST Smith, J Macadangdang, W Leung, MA Laflamme, DH Kim
Biotechnology advances 35 (1), 77-94, 2017
Characterization and optimization of a simple, repeatable system for the long term in vitro culture of aligned myotubes in 3D
AST Smith, S Passey, L Greensmith, V Mudera, MP Lewis
Journal of cellular biochemistry 113 (3), 1044-1053, 2012
In vitro differentiation of functional human skeletal myotubes in a defined system
X Guo, K Greene, N Akanda, AST Smith, M Stancescu, S Lambert, ...
Biomaterials science 2 (1), 131-138, 2014
The effect of cell density on the maturation and contractile ability of muscle derived cells in a 3D tissue‐engineered skeletal muscle model and determination of the cellular …
V Mudera, AST Smith, MA Brady, MP Lewis
Journal of cellular physiology 225 (3), 646-653, 2010
Nanopatterned human iPSC-based model of a dystrophin-null cardiomyopathic phenotype
J Macadangdang, X Guan, AST Smith, R Lucero, S Czerniecki, ...
Cellular and molecular bioengineering 8 (3), 320-332, 2015
A functional system for high-content screening of neuromuscular junctions in vitro
AST Smith, CJ Long, K Pirozzi, JJ Hickman
Technology 1 (01), 37-48, 2013
Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues
PY Mengsteab, K Uto, AST Smith, S Frankel, E Fisher, Z Nawas, ...
Biomaterials 86, 1-10, 2016
Micro-and nano-patterned conductive graphene–PEG hybrid scaffolds for cardiac tissue engineering
AST Smith, H Yoo, H Yi, EH Ahn, JH Lee, G Shao, E Nagornyak, ...
Chemical Communications 53 (53), 7412-7415, 2017
Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery
AST Smith, J Davis, G Lee, DL Mack, DH Kim
Drug discovery today 21 (9), 1387-1398, 2016
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro
AST Smith, CJ Long, K Pirozzi, S Najjar, C McAleer, HH Vandenburgh, ...
Journal of biotechnology 185, 15-18, 2014
Correlation of embryonic skeletal muscle myotube physical characteristics with contractile force generation on an atomic force microscope-based bio-microelectromechanical …
KL Pirozzi, CJ Long, CW McAleer, AST Smith, JJ Hickman
Applied physics letters 103 (8), 083108, 2013
Creating interactions between tissue-engineered skeletal muscle and the peripheral nervous system
AST Smith, SL Passey, NRW Martin, DJ Player, V Mudera, L Greensmith, ...
Cells Tissues Organs 202 (3-4), 143-158, 2016
Microphysiological systems and low-cost microfluidic platform with analytics
AST Smith, CJ Long, BJ Berry, C McAleer, M Stancescu, P Molnar, ...
Stem cell research & therapy 4 (1), 1-5, 2013
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
JW Miklas, E Clark, S Levy, D Detraux, A Leonard, K Beussman, ...
Nature communications 10 (1), 1-21, 2019
Advances and current challenges associated with the use of human induced pluripotent stem cells in modeling neurodegenerative disease
BJ Berry, AST Smith, JE Young, DL Mack
Cells Tissues Organs 205 (5-6), 331-349, 2018
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