|Microfabricated mammalian organ systems and their integration into models of whole animals and humans|
JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler
Lab on a Chip 13 (7), 1201-1212, 2013
|Multi-organ toxicity demonstration in a functional human in vitro system composed of four organs|
C Oleaga, C Bernabini, AST Smith, B Srinivasan, M Jackson, W McLamb, ...
Scientific reports 6 (1), 1-17, 2016
|How multi-organ microdevices can help foster drug development|
MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler
Advanced drug delivery reviews 69, 158-169, 2014
|Biomimetic 3D tissue models for advanced high-throughput drug screening|
KH Nam, AST Smith, S Lone, S Kwon, DH Kim
Journal of laboratory automation 20 (3), 201-215, 2015
|Nanotopography-induced structural anisotropy and sarcomere development in human cardiomyocytes derived from induced pluripotent stem cells|
D Carson, M Hnilova, X Yang, CL Nemeth, JH Tsui, AST Smith, A Jiao, ...
ACS applied materials & interfaces 8 (34), 21923-21932, 2016
|Characterization and optimization of a simple, repeatable system for the long term in vitro culture of aligned myotubes in 3D|
AST Smith, S Passey, L Greensmith, V Mudera, MP Lewis
Journal of cellular biochemistry 113 (3), 1044-1053, 2012
|Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening|
AST Smith, J Macadangdang, W Leung, MA Laflamme, DH Kim
Biotechnology advances 35 (1), 77-94, 2017
|In vitro differentiation of functional human skeletal myotubes in a defined system|
X Guo, K Greene, N Akanda, AST Smith, M Stancescu, S Lambert, ...
Biomaterials science 2 (1), 131-138, 2014
|A functional system for high-content screening of neuromuscular junctions in vitro|
AST Smith, CJ Long, K Pirozzi, JJ Hickman
Technology 1 (01), 37-48, 2013
|The effect of cell density on the maturation and contractile ability of muscle derived cells in a 3D tissue‐engineered skeletal muscle model and determination of the cellular …|
V Mudera, AST Smith, MA Brady, MP Lewis
Journal of cellular physiology 225 (3), 646-653, 2010
|Nanopatterned human iPSC-based model of a dystrophin-null cardiomyopathic phenotype|
J Macadangdang, X Guan, AST Smith, R Lucero, S Czerniecki, ...
Cellular and molecular bioengineering 8 (3), 320-332, 2015
|Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues|
PY Mengsteab, K Uto, AST Smith, S Frankel, E Fisher, Z Nawas, ...
Biomaterials 86, 1-10, 2016
|Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery|
AST Smith, J Davis, G Lee, DL Mack, DH Kim
Drug discovery today 21 (9), 1387-1398, 2016
|Micro-and nano-patterned conductive graphene–PEG hybrid scaffolds for cardiac tissue engineering|
AST Smith, H Yoo, H Yi, EH Ahn, JH Lee, G Shao, E Nagornyak, ...
Chemical Communications 53 (53), 7412-7415, 2017
|A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro|
AST Smith, CJ Long, K Pirozzi, S Najjar, C McAleer, HH Vandenburgh, ...
Journal of biotechnology 185, 15-18, 2014
|Correlation of embryonic skeletal muscle myotube physical characteristics with contractile force generation on an atomic force microscope-based bio-microelectromechanical …|
KL Pirozzi, CJ Long, CW McAleer, AST Smith, JJ Hickman
Applied physics letters 103 (8), 083108, 2013
|Creating interactions between tissue-engineered skeletal muscle and the peripheral nervous system|
AST Smith, SL Passey, NRW Martin, DJ Player, V Mudera, L Greensmith, ...
Cells Tissues Organs 202 (3-4), 143-158, 2016
|Microphysiological systems and low-cost microfluidic platform with analytics|
AST Smith, CJ Long, BJ Berry, C McAleer, M Stancescu, P Molnar, ...
Stem cell research & therapy 4 (S1), S9, 2013
|Advances and current challenges associated with the use of human induced pluripotent stem cells in modeling neurodegenerative disease|
BJ Berry, AST Smith, JE Young, DL Mack
Cells Tissues Organs 205 (5-6), 331-349, 2018
|TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes|
JW Miklas, E Clark, S Levy, D Detraux, A Leonard, K Beussman, ...
Nature communications 10, 2019