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Alfredo J. Guerra
Alfredo J. Guerra
Research Investigator - University of Michigan
Dirección de correo verificada de umich.edu
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The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor
H Reyes-Caballero, AJ Guerra, FE Jacobsen, KM Kazmierczak, D Cowart, ...
Journal of molecular biology 403 (2), 197-216, 2010
1162010
Metal site occupancy and allosteric switching in bacterial metal sensor proteins
AJ Guerra, DP Giedroc
Archives of biochemistry and biophysics 519 (2), 210-222, 2012
872012
Crystal structure of the zinc-dependent MarR family transcriptional regulator AdcR in the Zn (II)-bound state
AJ Guerra, CE Dann III, DP Giedroc
Journal of the American Chemical Society 133 (49), 19614-19617, 2011
812011
Allosteric inhibition of a zinc-sensing transcriptional repressor: insights into the arsenic repressor (ArsR) family
GC Campanello, Z Ma, NE Grossoehme, AJ Guerra, BP Ward, ...
Journal of molecular biology 425 (7), 1143-1157, 2013
412013
Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods
DK Chakravorty, B Wang, CW Lee, AJ Guerra, DP Giedroc, KM Merz
Journal of biomolecular NMR 56, 125-137, 2013
262013
Energetics of zinc-mediated interactions in the allosteric pathways of metal sensor proteins
DK Chakravorty, TM Parker, AJ Guerra, CD Sherrill, DP Giedroc, ...
Journal of the American Chemical Society 135 (1), 30-33, 2013
252013
Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability
JD Zwicker, NA Diaz, AJ Guerra, PD Kirchhoff, B Wen, D Sun, ...
Bioorganic & medicinal chemistry letters 28 (10), 1972-1980, 2018
192018
Structural features of apicomplexan pore-forming proteins and their roles in parasite cell traversal and egress
AJ Guerra, VB Carruthers
Toxins 9 (9), 265, 2017
182017
The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii
D Aghabi, M Sloan, G Gill, E Hartmann, O Antipova, Z Dou, AJ Guerra, ...
Nature Communications 14 (1), 3659, 2023
152023
Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites
AD Roberts, SC Nair, AJ Guerra, ST Prigge
Traffic 20 (8), 571-582, 2019
142019
A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species
GA Afanador, AJ Guerra, RP Swift, RE Rodriguez, D Bartee, KA Matthews, ...
Molecular microbiology 106 (3), 439-451, 2017
142017
Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS
JD Zwicker, D Smith, AJ Guerra, JR Hitchens, N Haug, S Vander Roest, ...
ACS chemical neuroscience 11 (16), 2450-2463, 2020
102020
Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress
AJ Guerra, O Zhang, CME Bahr, MH Huynh, J DelProposto, WC Brown, ...
PLoS pathogens 14 (12), e1007476, 2018
102018
Backbone and sterospecific methyl side chain resonance assignments of the homodimeric zinc sensor AdcR (32 kDa) in the apo-and Zn (II)-bound states
AJ Guerra, DP Giedroc
Biomolecular NMR assignments 8, 11-14, 2014
72014
Crystal structure of lipoate‐bound lipoate ligase 1, LipL1, from Plasmodium falciparum
AJ Guerra, GA Afanador, ST Prigge
Proteins: Structure, Function, and Bioinformatics 85 (9), 1777-1783, 2017
42017
The vacuolar iron transporter mediates iron detoxification inToxoplasma gondii
D Aghabi, M Sloan, Z Dou, AJ Guerra, CR Harding
12021
mSphere of Influence: Ushering in the CRISPR Revolution to Toxoplasma Biology
AJ Guerra
Msphere 4 (4), 10.1128/msphere. 00307-19, 2019
2019
The Metalloregulatory Zinc Site in Streptococcus Pneumoniae Adcr, a Zinc-Activated Marr Family
H Reyes-Caballero, AJ Guerra, FE Jacobsen, KM Kazmierczak, D Cowart, ...
J. Mol. Biol 403: 197, 2010, 2013
2013
Metal‐Regulated Gene Expression
AJ Guerra, DP Giedroc
Elsevier, 2013
2013
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Artículos 1–19