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Ram Balasubramanian
Ram Balasubramanian
Scientist Kite pharma
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Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats
K Ravi, B Ramachandran, S Subramanian
Biological and Pharmaceutical Bulletin 27, 1212-1217, 2004
2922004
Effect of Eugenia jambolana seed kernel on antioxidant defense system in streptozotocin-induced diabetes in rats
K Ravi, B Ramachandran, S Subramanian
Life sciences 75 (22), 2717-2731, 2004
2592004
A2B adenosine receptor blockade inhibits growth of prostate cancer cells
Q Wei, S Costanzi, R Balasubramanian, ZG Gao, KA Jacobson
Purinergic signalling 9 (2), 271-280, 2013
1212013
G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions
KA Jacobson, R Balasubramanian, F Deflorian, ZG Gao
Purinergic signalling 8 (3), 419-436, 2012
1202012
Structure− Activity Relationship of (N)-Methanocarba Phosphonate Analogues of 5′-AMP as Cardioprotective Agents Acting Through a Cardiac P2X Receptor
TS Kumar, SY Zhou, BV Joshi, R Balasubramanian, T Yang, BT Liang, ...
Journal of medicinal chemistry 53 (6), 2562-2576, 2010
932010
Protective effect of macrocyclic binuclear oxovanadium complex on oxidative stress in pancreas of streptozotocin induced diabetic rats
B Ramachandran, K Ravi, V Narayanan, M Kandaswamy, S Subramanian
Chemico-biological interactions 149 (1), 9-21, 2004
812004
Structure–activity relationship of purine and pyrimidine nucleotides as ecto-5′-nucleotidase (CD73) inhibitors
A Junker, C Renn, C Dobelmann, V Namasivayam, S Jain, K Losenkova, ...
Journal of medicinal chemistry 62 (7), 3677-3695, 2019
582019
Pyrimidine Ribonucleotides with Enhanced Selectivity as P2Y6 Receptor Agonists: Novel 4-Alkyloxyimino,(S)-Methanocarba, and 5′-Triphosphate γ-Ester Modifications†
H Maruoka, MO Barrett, H Ko, DK Tosh, A Melman, LE Burianek, ...
Journal of medicinal chemistry 53 (11), 4488-4501, 2010
492010
Enhancement of Glucose Uptake in Mouse Skeletal Muscle Cells and Adipocytes by P2Y6 Receptor Agonists
R Balasubramanian, B Robaye, JM Boeynaems, KA Jacobson
PloS one 9 (12), e116203, 2014
482014
Effect of macrocyclic binuclear oxovanadium complex on tissue defense system in streptozotocin-induced diabetic rats
B Ramachandran, K Ravi, V Narayanan, M Kandaswamy, S Subramanian
Clinica chimica acta 345 (1-2), 141-150, 2004
452004
Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic β cells
R Balasubramanian, IR de Azua, J Wess, KA Jacobson
Biochemical pharmacology 79 (9), 1317-1326, 2010
432010
Novel fluorescent antagonist as a molecular probe in A< sub> 3</sub> adenosine receptor binding assays using flow cytometry
E Kozma, TS Kumar, S Federico, K Phan, R Balasubramanian, ZG Gao, ...
Biochemical pharmacology 83 (11), 1552-1561, 2012
422012
Structure-Based Design of 3-(4-Aryl-1H-1,2,3-triazol-1-yl)-Biphenyl Derivatives as P2Y14 Receptor Antagonists
A Junker, R Balasubramanian, A Ciancetta, E Uliassi, E Kiselev, ...
Journal of medicinal chemistry 59 (13), 6149-6168, 2016
402016
Probing biased/partial agonism at the G protein-coupled A 2B adenosine receptor
ZG Gao, R Balasubramanian, E Kiselev, Q Wei, KA Jacobson
Biochemical pharmacology 90 (3), 297-306, 2014
382014
Insulin mimetic effects of macrocyclic binuclear oxovanadium complexes on streptozotocin‐induced experimental diabetes in rats
B Ramachandran, M Kandaswamy, V Narayanan, S Subramanian
Diabetes, Obesity and Metabolism 5 (6), 455-461, 2003
372003
Virtual screening leads to the discovery of novel non-nucleotide P2Y< sub> 1</sub> receptor antagonists
S Costanzi, T Santhosh Kumar, R Balasubramanian, T Kendall Harden, ...
Bioorganic & medicinal chemistry 20 (17), 5254-5261, 2012
292012
Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y 14 receptor
E Kiselev, R Balasubramanian, E Uliassi, KA Brown, K Trujillo, V Katritch, ...
Bioorganic & medicinal chemistry letters 25 (21), 4733-4739, 2015
252015
4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y2, P2Y4, and P2Y6 Receptors
PS Jayasekara, MO Barrett, CB Ball, KA Brown, E Hammes, ...
Journal of medicinal chemistry 57 (9), 3874-3883, 2014
252014
John Daly Lecture: Structure-guided Drug Design for Adenosine and P2Y Receptors
KA Jacobson, ZG Gao, S Paoletta, E Kiselev, S Chakraborty, ...
Computational and structural biotechnology journal 13, 286-298, 2015
222015
Pyrimidine nucleotides containing a (S)-methanocarba ring as P2Y 6 receptor agonists
KS Toti, S Jain, A Ciancetta, R Balasubramanian, S Chakraborty, ...
MedChemComm 8 (10), 1897-1908, 2017
182017
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