| Regulation of protein kinases: controlling activity through activation segment conformation B Nolen, S Taylor, G Ghosh Molecular cell 15 (5), 661-675, 2004 | 1340 | 2004 |
| Characterization of two classes of small molecule inhibitors of Arp2/3 complex BJ Nolen, N Tomasevic, A Russell, DW Pierce, Z Jia, CD McCormick, ... Nature 460 (7258), 1031-1034, 2009 | 583 | 2009 |
| Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change B Hetrick, MS Han, LA Helgeson, BJ Nolen Chemistry & biology 20 (5), 701-712, 2013 | 366 | 2013 |
| Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2 JCK Ngo, S Chakrabarti, JH Ding, A Velazquez-Dones, B Nolen, ... Molecular cell 20 (1), 77-89, 2005 | 265 | 2005 |
| Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex SC Ti, CT Jurgenson, BJ Nolen, TD Pollard Proceedings of the National Academy of Sciences 108 (33), E463-E471, 2011 | 165 | 2011 |
| Processive phosphorylation of alternative splicing factor/splicing factor 2 BE Aubol, S Chakrabarti, J Ngo, J Shaffer, B Nolen, XD Fu, G Ghosh, ... Proceedings of the National Academy of Sciences 100 (22), 12601-12606, 2003 | 149 | 2003 |
| Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP LA Helgeson, BJ Nolen Elife 2, 2013 | 148 | 2013 |
| Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP BJ Nolen, RS Littlefield, TD Pollard Proceedings of the National Academy of Sciences 101 (44), 15627-15632, 2004 | 108 | 2004 |
| The structure of Sky1p reveals a novel mechanism for constitutive activity B Nolen, CY Yun, CF Wong, JA McCammon, XD Fu, G Ghosh Nature Structural and Molecular Biology 8 (2), 176, 2001 | 104 | 2001 |
| Dip1 defines a class of Arp2/3 complex activators that function without preformed actin filaments AR Wagner, Q Luan, SL Liu, BJ Nolen Current Biology 23 (20), 1990-1998, 2013 | 91 | 2013 |
| Structural basis for regulation of Arp2/3 complex by GMF Q Luan, BJ Nolen Nature Structural and Molecular Biology 20 (9), 1062, 2013 | 82 | 2013 |
| Mechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coronin SL Liu, KM Needham, JR May, BJ Nolen Journal of Biological Chemistry 286 (19), 17039-17046, 2011 | 81 | 2011 |
| Insights into the influence of nucleotides on actin family proteins from seven structures of Arp2/3 complex BJ Nolen, TD Pollard Molecular cell 26 (3), 449-457, 2007 | 80 | 2007 |
| Nucleotide-mediated conformational changes of monomeric actin and Arp3 studied by molecular dynamics simulations P Dalhaimer, TD Pollard, BJ Nolen Journal of molecular biology 376 (1), 166-183, 2008 | 72 | 2008 |
| Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks LA Helgeson, JG Prendergast, AR Wagner, M Rodnick-Smith, BJ Nolen Journal of Biological Chemistry 289 (42), 28856-28869, 2014 | 69 | 2014 |
| Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex M Rodnick-Smith, Q Luan, SL Liu, BJ Nolen Proceedings of the National Academy of Sciences 113 (27), E3834-E3843, 2016 | 63 | 2016 |
| Incompatibility with Formin Cdc12p Prevents Human Profilin from Substituting for Fission Yeast Profilin INSIGHTS FROM CRYSTAL STRUCTURES OF FISSION YEAST PROFILIN OC Ezezika, NS Younger, J Lu, DA Kaiser, ZA Corbin, BJ Nolen, ... Journal of Biological Chemistry 284 (4), 2088-2097, 2009 | 62 | 2009 |
| Structure and biochemical properties of fission yeast Arp2/3 complex lacking the Arp2 subunit BJ Nolen, TD Pollard Journal of Biological Chemistry 283 (39), 26490-26498, 2008 | 54 | 2008 |
| Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state M Shaaban, S Chowdhury, BJ Nolen Nature Structural & Molecular Biology, 1-8, 2020 | 48 | 2020 |
| Structural Characterization and Computer‐Aided Optimization of a Small‐Molecule Inhibitor of the Arp2/3 Complex, a Key Regulator of the Actin Cytoskeleton AW Baggett, Z Cournia, MS Han, G Patargias, AC Glass, SY Liu, BJ Nolen ChemMedChem 7 (7), 1286-1294, 2012 | 48 | 2012 |
