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Inês Pires da Silva
Inês Pires da Silva
Melanoma Institute Australia
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Distinct immune cell populations define response to anti-PD-1 monotherapy and anti-PD-1/anti-CTLA-4 combined therapy
TN Gide, C Quek, AM Menzies, AT Tasker, P Shang, J Holst, J Madore, ...
Cancer cell 35 (2), 238-255. e6, 2019
6242019
Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 BlockadeTim-3 Blockade Reverses Melanoma NK-Cell Exhaustion
IP da Silva, A Gallois, S Jimenez-Baranda, S Khan, AC Anderson, ...
Cancer immunology research 2 (5), 410-422, 2014
3782014
Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L) 1 monotherapy: a multicentre, retrospective, cohort study
IP da Silva, T Ahmed, ILM Reijers, AM Weppler, AB Warner, JR Patrinely, ...
The Lancet Oncology 22 (6), 836-847, 2021
1332021
Site‐specific response patterns, pseudoprogression, and acquired resistance in patients with melanoma treated with ipilimumab combined with anti–PD‐1 therapy
I Pires da Silva, S Lo, C Quek, M Gonzalez, MS Carlino, GV Long, ...
Cancer 126 (1), 86-97, 2020
1302020
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
L Haas, A Elewaut, CL Gerard, C Umkehrer, L Leiendecker, M Pedersen, ...
Nature Cancer 2 (7), 693-708, 2021
1232021
Serum‐based miRNAs in the prediction and detection of recurrence in melanoma patients
NH Fleming, J Zhong, IP Da Silva, E Vega‐Saenz de Miera, B Brady, ...
Cancer 121 (1), 51-59, 2015
1062015
Reversal of natural killer cell exhaustion by TIM-3 blockade
A Gallois, I Silva, I Osman, N Bhardwaj
Oncoimmunology 3 (12), e946365, 2014
1022014
Reversal of NK cell exhaustion in advanced melanoma by Tim-3 blockade. Cancer Immunol Res. 2014; 2: 5 410–22. doi: 10.1158/2326-6066
IP da Silva, A Gallois, SJ Baranda, S Khan, AC Anderson, VK Kuchroo
CIR-13-0171, 0
86
Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance
F Newell, IP da Silva, PA Johansson, AM Menzies, JS Wilmott, V Addala, ...
Cancer cell 40 (1), 88-102. e7, 2022
812022
Integrated molecular and immunophenotypic analysis of NK cells in anti-PD-1 treated metastatic melanoma patients
H Lee, C Quek, I Silva, A Tasker, M Batten, H Rizos, SY Lim, T Nur Gide, ...
OncoImmunology 8 (2), e1537581, 2019
792019
Systemic therapy in advanced melanoma: integrating targeted therapy and immunotherapy into clinical practice
IP Silva, GV Long
Current opinion in oncology 29 (6), 484-492, 2017
792017
New perspectives on the conservative management of osteoradionecrosis of the mandible: a literature review
DA Costa, TP Costa, EC Netto, N Joaquim, I Ventura, AC Pratas, ...
Head & neck 38 (11), 1708-1716, 2016
722016
Close proximity of immune and tumor cells underlies response to anti-PD-1 based therapies in metastatic melanoma patients
TN Gide, IP Silva, C Quek, T Ahmed, AM Menzies, MS Carlino, RPM Saw, ...
Oncoimmunology 9 (1), 1659093, 2020
682020
Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant MelanomaGenetic Profile and Outcomes of V600E/V600K-Treated Melanoma
I Pires da Silva, KYX Wang, JS Wilmott, J Holst, MS Carlino, JJ Park, ...
Clinical Cancer Research 25 (4), 1272-1279, 2019
632019
Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition
A Rogiers, IP Da Silva, C Tentori, CA Tondini, JM Grimes, MH Trager, ...
Journal for immunotherapy of cancer 9 (1), 2021
602021
Comprehensive analysis of cutaneous and uveal melanoma liver metastases
EP Hoefsmit, EA Rozeman, TM Van, P Dimitriadis, O Krijgsman, ...
Journal for immunotherapy of cancer 8 (2), 2020
522020
Clinical Models to Define Response and Survival With Anti–PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma
I Pires da Silva, T Ahmed, JL McQuade, CA Nebhan, JJ Park, JM Versluis, ...
Journal of Clinical Oncology 40 (10), 1068-1080, 2022
492022
Analysis of recurrence patterns in acral versus nonacral melanoma: should histologic subtype influence treatment guidelines?
PV Gumaste, NH Fleming, I Silva, RL Shapiro, RS Berman, J Zhong, ...
Journal of the National Comprehensive Cancer Network 12 (12), 1706-1712, 2014
452014
Recurrent hotspot SF3B1 mutations at codon 625 in vulvovaginal mucosal melanoma identified in a study of 27 Australian mucosal melanomas
C Quek, RV Rawson, PM Ferguson, P Shang, I Silva, RPM Saw, ...
Oncotarget 10 (9), 930, 2019
412019
Identification of a Novel Pathogenic Germline KDR Variant in MelanomaA Novel Pathogenic Germline Variant in Melanoma
IP Silva, A Salhi, KM Giles, M Vogelsang, SW Han, N Ismaili, KP Lui, ...
Clinical Cancer Research 22 (10), 2377-2385, 2016
402016
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